Tag: "genotoxin" at biology news
Molecular image of genotoxin reveals how bacteria damage human DNA
...bins' structure of CDT visually confirms that this genotoxin
is made up of three subunits, including one called CdtB that cleaves, or cuts, DNA. According to Stebbins' model, the three-unit toxin contains a long, deep groove, a cluster of ring-shaped molecules, called the "aromatic patch," and a dangling prot...
Study finds first evidence COX-2 enzymes can regulate DNA damage
...es that the ability of COX-2 inhibitors to prevent genotoxin
formation during cellular oxidative stress suggests a potential usefulness in cancer prevention and that new drugs could be developed to remove COX-2 derived cellular genotoxins. ...