Clue found on breast tumors distinguishes patients with better survival odds
...tient materials that included over 1,100 patients, giving the study a solid statistical basis. Also, unlike some marker assays or tests, the assay for Stat5 is simple, inexpensive, and can be rapidly adapted to routine analysis in pathology laboratories using standard procedures. "Although hurdles remain...Cutting back on cigarettes: when less is more
...ortunately, our research suggests that this may be giving them a false sense of security." Ahijevych, who has been studying smoking cessation for sixteen years, says the best way to quit is through the use of pharmacotherapy a broad reference that includes various patches, gums and other prescription items...Gene discovered for Cornelia de Lange syndrome, a disabling genetic disease
...on chromosome 5, which they named NIPBL. Mutations giving rise to Cornelia de Lange syndrome occur at different locations within that gene. NIPBL stands for Nipped B-like, because the human gene produces proteins similar to those produced by the Nipped-B gene in fruit flies. The insect gene was called Nippe...Plant-like enzyme acts as key life cycle switch in malaria parasite
... stages of the parasite's life cycle, and they are giving us great insights into the molecular components involved in signalling and regulation of the parasite." "We will use this method in future to dissect out more signalling pathways involved in the malaria parasite's life cycle. To a cell biologist it i...22-amino acid bacterium created by Scripps scientists
... will encode for the new amino acid in that place, giving Schultz and his colleagues a way to site-specifically incorporate novel amino acids into proteins expressed by the E. coli. Similarly, Schultz and his colleagues made an engineered tRNA/synthetase orthogonal pair from the polar archean organism Pyr...Sediments in many Central Valley streams contain toxic levels of pyrethroid pesticides
...e said. "I'm realistic. You can't ban them without giving farmers another choice, so you have to find some way of making them work better under the conditions in which they're being used. 'Best management practices,' such as introducing buffer strips and wetlands, may reduce pesticide loads in aquatic syste...Transplant rejection averted by simple light exposure in Stanford animal study
...lanted mice by exposing them to ultraviolet light, giving the animals mild sunburn. Transplanted mice that received this treatment experienced no GVHD while those that didn't showed severe signs of the disease, said Edgar Engleman, MD, professor of pathology and medicine and senior author of the study. "The...Insights on stroke from the peripheral blood suggest ways to develop markers and therapies
...ution when the infarct zone is expanding and when giving drugs to restore blood flow is most likely to prevent damage to the brain tissue. MRI and other imaging modalities also allowed clinicians to detect ischemic lesions as early as the first half hour after symptom onset and differentiate between patie......th which a SEM works to pass through unobstructed, giving scientists a clear view of what lies within, without the use of tricky, tissue-distorting procedures. Researchers hope the new method will advance the studies of biological materials, such as the lipids that make up fat, which are easily destroyed by...Discovery could improve anemia treatment in patients
...as been made between HFE, inflammation and anemia giving us a clear target to aim for a new treatment for anemia of chronic disease." ...Hemochromatosis, inflammation and anemia
...as been made between HFE, inflammation and anemia giving us a clear target to aim for a new treatment for ACD."...Breakthrough Clemson research appears in Science
...skin, induced shell growth. "New technologies are giving scientists the tools they need to answer the tough questions," said Andrew Mount, adjunct assistant professor of biological sciences at Clemson University and lead author of the article. When the Clemson researchers used a scanning electron microsco...Ferns diversified in shadow of flowering plants
...h responded to a wider range of light wavelengths, giving ferns an evolutionary advantage in the low-light conditions in angiosperm forests. "Angiosperm forests are ecologically and structurally more complex than are the more uniform forests dominated by the conifers or cycads present in more ancient forest...Bioreactor boosts chemical fermentation by 50 percent: study
...cinate production had decreased. Aside from giving Swiss cheese its characteristic smell and flavor, propionic acid is often used as a preservative and flavor enhancer for a wide variety of cheeses and baked goods. In the chemical industries, it's used as an ingredient for dyes, perfumes, phar...Case researchers substantiate bacterial link to preterm birth through mice studies
... affected by the bacteria and within 72 hours were giving birth to stillborn pups. Follow-up microbiology studies were done on the placentas and amniotic fluids of women who have undergone premature labor. While the studies were done years ago, Han said no one make the link until recently to verify the pr...Biochemistry and Molecular Biology: Research at the Interface of Biochemistry and Human Health
...y media briefings will be held during the meeting, giving reporters an opportunity to hear leading scientists explain their research findings in lay language and to answer and to answer reporters' questions. Meeting updates will be posted at http://www.eurekalert.org . Visit http://www.asbmb.org/meetin...Discoveries reveal that gene regulation is bipolar
...understand a gene's function and its regulation by giving them some useful clues about where to start looking. "If your favorite gene has a TATA box then there is a good chance that it may be subjected to a lot of regulation, and there is a good chance that it may be responding to environmental stress or o...Rb protein's role in retina development is key to understanding devastating eye cancer
...ll is a "parent" cell that divides and multiplies, giving rise to specific types of cells. One way the researchers solved the problem of embryos dying from lack of Rb was by taking advantage of the fact that the retina is still developing in newborn mice. The team used a virus to insert a gene for E1A--a p...Should publicly funded research be free and available to the public?
...-reviewed research papers freely available online, giving anyone with access to the Internet freedom to "read, download, print, copy and redistribute any published article, or to use its contents in derivative works, such as databases, textbooks or other teaching materials." The PLoS board of directors prom...Scientists urge caution when releasing engineered organisms into environment
...ulations," Snow said. Finally, the panel calls for giving broader training to ecologists, agricultural scientists, molecular biologists, etc., to adequately address the report's recommendations. Collaborative, multidisciplinary research is important for learning about the environmental risks and benefits of...