Duke Researchers Discover Central Role Of Nitric Oxide In Hemoglobin Action
...ind NO." Further experimentation by the group uncovered the intricate interplaybetween hemoglobin, oxygen, NO and carbon dioxide: After hemoglobin loads up oxygen and SNO in the lung, the hemoglobin-triotravels down arteries through the heart and into the rest of the body todeliver its ...Enzyme's "Magic" May Hold Key to Anticancer and Antimicrobial Drugs
...ings of one topoisomerase have been laid bare by a group of researchers led by NIGMS grantee Dr. James C. Wang, the Mallinckrodt Professor of Biochemistry and Molecular Biology at Harvard University. In the January 18 issue of Nature , the scientists described the...Key to Triplet Repeat Brain Diseases Open Door For New Way To Understand, Treat Genetic Diseases"
...s is an observationthat provides a mechanism for a group of diseases." If drugs could block the protein i...s was a key to the discovery, Vancesaid. "We are a group of clinicians, geneticists and molecular biologists.Only by working across disciplines could we have...Second Breast Cancer Gene Located
... "Is there a BRCA3?" Futreal asked. "There is a group offamilies that cannot be attributed to either BRCA1 or BRCA2. Now we needto discover whether there is one gene, or a cluster of unrelated mutations,behind those cancers." The report's co-authors include researchers from Chester Beatty Labo...Heat-loving Microbe Repairs Its DNA With Light
...t. Sulfolobus acidocaldarius is one of a special group ofmicro-organisms, commonly called "hyperthermophiles." Theseorganisms require extremely high temperatures to grow andreproduce, and they have been recovered by microbiologists overthe past 25 years from various hot springs, undersea vents, andother ......ntharidin is not fire-colored beetles but rather a group of beetles generally known as blister beetles. They owe their blistering reputation to cantharidin, which causes severe irritation of the skin when touched -- and of the urogenital tract when swallowed. Because of its purported stimulative effec...International Research Team Clones New Skin Cancer Gene
...through 40 genes from this region. In May, Bale's group reported isolation of PTC, a human gene similar to a previously reported fruit fly gene. "Nobody had a clue that this gene had anything to do with human cancer, but some of the features in fruit flies were strangely similar to the birth defects in NB...Humble Pocket Gophers Shed Light On The Genetic Fortitude Of Cheetahs
...Humboldt County in northern California and a third group from the Carmel Valley. Gophers within each of the northern populations were so similar genetically that a DNA fingerprinting analysis by coworker David Foran could not separate individuals. The Carmel Valley gophers had much higher genetic variabili...Hawaiian Whales Show 'No Overt Response' To Sounds Of ATOC Simulation
...ound periods were practically identical, Frankel's group reported. The simulation experiments were conducted in mornings and afternoons. First, shore observers monitored normal whale behavior for at least 25 minutes. Then a 25-minute session of ATOC sound (or no-sound, for experimental "controls") c...Cooking And Salad Oils Could Lubricate Cars, Boats, Machines
... surfaces, is the only chemistry-focused tribology group in the U.S....Salvage Gene Is At The Root Of Many Mutations
...a DNA polymerase -- recently announced by the same group ofscientists in Science -- to resume copying the DNA strand. This saves the cell from certain death, but its survivalcarries a potentially steep price: The arbitrary placement of a cytosine base may change the genetic code and cause amutation. While ...Major Plant Genome Research Project Underway
... Research Project was launched by an international group of scientists who recognized the need for study of one plant with the basic properties of all plants. "During the past several years, Arabidopsis has become established worldwide as the species of choice for molecular genetic studies of plant biol......attern from the HVc corresponded to a syllable, or group of notes, lasting in the range of a quarter of a second. Margoliash said the goal now is to see how the brain learns the song, by comparing adult birds to immature ones or those that are raised in isolation or have diminished hearing. "What we can ho...Component In Soy Products May Be Substitute For Estrogen Treatment
...lesterol diets. Inaddition to a control group, one group ate soy protein with a standard levelof 56 milligr...ecause of a loss of bone calcium and protein. The group that consumed the isolated soy proteins, regardless of isoflavonecontent, saw the greatest improveme...Researchers Identify A New Cellular Structure: The "Dumposome"
...ty of Rochester professor of biology who led the group ofresearchers. "It's basically a little garbage disposal for eating extra DNA." Dumposomes appear only briefly during the life cycle of Tetrahymena. Over a five-hour period during reproduction,molecules of a structural protein known as Pdd1p coa...Cholesterol Anchor Helps Signaling Proteins Direct Development
...ientists report that hedgehog proteins, an unusual group of proteins that help shape many features of a developing embryo, pick up molecules of cholesterol to facilitate their work. Researchers have long known that completely suppressing cholesterol production leads to birth defects in animals; the new wor...Researchers Find Genetic Clues To Intestinal Disease
...inct disorders, this is the first large study of a group of families that confirms those suggestions," says Theodore M. Bayless, M.D., professor of medicine and gastroenterology. The findings have prompted Bayless and his co-worker, Steven Brant, M.D., toencourage people with a family history of Crohn's d...Behemoth Animals May Follow Same Extinction Patterns
... what,at its height during the late Miocene, was a group of some 30 types of animalsroaming the Earth. "Interestingly, at their height, dinosaurs also have a diversity ofabout 30 species," Cuffey says. Cuffey and Joey H. Eichelberger, a Penn State undergraduate, compared thediversity of dinosaurs and p...Scientists Identify Retrovirus-Like Components In Corn Genome
...armless, Bennetzen says. In the study, Bennetzen's group analyzed a region of the maize genome that contained two genes. The group discovered 10 different classes of retrotransposons within the region, with each class having 10 to ......y to regenerate its neural connections. The Purdue group now is conducting follow-up studies to see what role NOS may play in neural regeneration. The findings may someday be applied to research in human spinal regeneration. Details of the study were presented Nov. 21 at the annual meeting of the Society f...