Tag: "halted" at biology news

New anti-inflammatory strategy for cancer therapy identified by UCSD researchers

... of malignant tumors beyond the original site, was halted with inhibition of either one of two naturally occurring substances, a pro-inflammatory protein called nuclear factor-kappa B (NF-kB) or an inflammatory mediator called tumor necrosis factor alpha (TNFα). The result, published in the September ...

Early clinical treatment can halt progression of Alzheimer's disease, UCI researchers find

... arising from a second type of brain lesion, which halted the progression of the disease. Researchers also found that the earlier the treatment begins, the better the chances of success findings that have similar implications for people, emphasizing the need for better means of early diagnosis and treatmen...

Female infertility cAMP

...ammals, the development of the egg in the ovary is halted until just before ovulation, at which point the final cellular division to form the egg, called meiosis, is completed. Researchers have shown that this final step in egg maturation can be blocked by a chemical called cyclic AMP (cAMP) in a test tube,...

JCI Table of Contents, 15 July 2004

...ammals, the development of the egg in the ovary is halted until just before ovulation, at which point the final cellular division to form the egg, called meiosis, is completed. Researchers have shown that this final step in egg maturation can be blocked by a chemical called cyclic AMP (cAMP) in a test tube,...

Herpes tool allows researchers to customize Alzheimer's vaccine

... brains of several participants, and the study was halted last year because of the danger. With funding from the National Institutes of Health, Federoff and William Bowers, Ph.D., assistant professor of Neurology, set out to create a vaccine without the harmful side effects, by boosting part of the immune...

Study identifies which patients can benefit from targeted lung cancer drug and why

...ine on April 29. "Imatinib (GleevecTM) [which has halted or shrunk tumors in patients with a form of leukemia and digestive-system tumor] is probably the best-known example of a drug that works by targeting a specific, mutated tyrosine kinase," says William Sellers, M.D., who is co-senior author of the stu...

Tips from the Journals of the American Society for Microbiology

...ine, such as the dangerous heart inflammation that halted a recent clinical trial. "We demonstrated here that a DNA vaccine compromised of four VACV genes and administered by gene gun is capable of protecting nonhuman primates against severe monkeypox," say the researchers. "Such a vaccine would contr...

JCI table of contents, March 1 2004

...sion in parallel revealed that the immune reaction halted carcinogenesis and reverted neoplastic lesions to an early stage. This study highlights the potential of a combinatorial approach to vaccination for the prevention and suppression of neoplastic lesions. TITLE: Concordant morphologic and gene expressi...

Surveillance and containment would be effective intervention against deliberate smallpox attack

... against smallpox, and many states had temporarily halted their smallpox vaccination programs. Although routine smallpox vaccinations were stopped in 1972, recent studies have shown that previously vaccinated individuals retain substantial immunity. In the current study, the Emory investigators constructed...

First gene therapy approved

... the viruses used in the French gene therapy trial halted last year after two boys developed leukaemia. Anderson, who has agreed to become an unpaid adviser to SiBiono, says the company's adenovirus is relatively simple compared with the gene-delivery systems being developed in the west. "But sometimes sim...

Breast cancer can be reversed in laboratory mice, scientists report

... single gene known as beta-1 integrin prevented or halted breast cancer growth in laboratory mice. Beta-1 integrin is a principal regulator of normal breast tissue growth and survival, but if the gene malfunctions, it can directly initiate breast tumors. The new work demonstrates that knocking out the beta-...

Newly identified gene may halt fuzzy, moldy fruit

...testing. This allowed them to determine which gene halted the fungus' invasion. "We want to understand how plants resist Botrytis, what biological events occur when plants perceive that this fungus or other necrotrophic pathogens are present," Mengiste said. Botrytis is a necrotrophic pathogen, meaning it o...

Injection prevents blinding blood vessel growth in mice

... into the eyes or bloodstreams of mice, scientists halted new blood vessel growth in the rodents' eyes and stopped existing blood vessels from leaking. Study results were published recently in the Journal of Cellular Physiology. VEGF-TRAP was designed to antagonize vascular endothelial growth factor (VEG...

Copper chelation is a promising new therapy for clogged arteries

...g of arteries following balloon angioplasty can be halted by copper chelation therapy. Preventing the function of copper in the body stops arteries from reclogging following the mechanical stress of removing arterial obstructions through angioplasty. The therapy works by limiting the cellular export of gr...

Q Fever microbe's genome is deciphered

... stockpile was destroyed after the U.S. government halted its biowarfare program in 1969. The former Soviet Union also conducted Q Fever bioweapons research during the Cold War....

'Europeans and biotechnology' survey of public perception

...echnology, in many European countries the trend is halted in the latest survey. In the period 1999-2002, optimism has increased to the level seen in the early 1990s. This rise in optimism holds for the all the EU Member States with the exception of Germany and the Netherlands, where such a rise was observe...

Aspirin prevents polyps in colon cancer patients

... of the study. The study was halted when an independent data and safety monitoring board found the statistics about the benefits of aspirin so compelling, it felt that patients in the placebo arm should be free to choose to...

Pregnancy prevention efforts rely on neighborhood ties

...t in the topic at all were the ones where activity halted after the planning phase. In the case of the mostly white neighborhood, for instance, many community members did not think that teen pregnancy was a problem. In the predominantly African-American neighborhood, residents said they were more worried ab...

Too much oxygen on the cell biology bench? New study suggests so

...ht. This suggests that growth halted by hyperoxia can be reversed, at least when the hyperoxic insult is short, Sen said. He also noted that it takes about 15 to 20 minutes before a change in oxygen level begins to affect a cel...

Genome of potential bioterror agent seqenced

... stockpile was destroyed after the U.S. government halted its biowarfare program in 1969. Other countries also developed Brucella weapons during the Cold War. Claire M. Fraser, Ph.D., president and director of TIGR, said: "The B. suis sequencing project provides important new information about this infectio...

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