The future of HIV therapeutics is brightening, according to Gladstone Institutes Director
...investigators and scientists around the world have helped accelerate clinical development of CCR5 antagonists as a new class of anti-HIV drugs. Several major pharmaceutical companies are now racing to the finishing line. These advances address but one of the three steps required for successful entry of th...Washington University in St. Louis plays key role in sequencing moss genome
...pported (BASF) program at Freiburg University, all helped develop a range of molecular and bioinformatics resources including EST collections, analysis of gene expression and mutant collections. Quatrano said that the collaborators are hopeful that, as sequencing gets under way, the wider community of pla...Review article makes case for a new source of cells in the body
... jury remains out on that question, the cells have helped Dr. Dickinson find new direction in his research: working to learn more about the cells Dr. Sohal first saw in 1995 traveling out of the neural tube of a three-day-old chick embryo. Dr. Dickinson got a baptism by immersion as lead author on an invite...Tiny molecules have big potential as cancer drugs, Stanford researcher believes
... of two types of cancer. They found the cathepsins helped build blood vessels to the tumors as well as increase tumor growth and invasiveness. The team also tried giving a broad-spectrum cathepsin inhibitor to some cancerous mice and found that it slowed tumor development both in early and late stages of gr...Nevada researcher re-ignites mammal reproduction debate
...f Natural Resources and Environmental Science, has helped to disprove critics of a scientific theory developed in 1973. At that time, ecologist Bob Trivers and mathematician Dan Willard said that large healthy mammals produce more male offspring when living in good conditions, such as areas where there is...Nucleic acid-amplification testing further safeguards nation's blood supply
...alth. Nucleic acid-amplification testing (NAT) has helped prevent the transmission of approximately five HIV-1 infections and 56 hepatitis C virus (HCV) infections each year since it began being used in the United States as an investigational screening test in mid-1999. The study is published in the August...Gene linked to cleft lip and palate identified
....D., medical director of the March of Dimes, which helped fund the study. "This new finding brings us closer to understanding the multiple genetic factors underlying these very serious birth defects, with probable environmental effects." The discovery also has important implications for genetic counseling f...New model can aid in understanding immune system diseases
...ts specific organs or tissues. Previous UI studies helped show that this viral protein mimics a normal cellular process in humans. In that process, a protein called CD40 signals B cells (white blood cells) to divide and make antibodies against infection, then terminates the signal when the need for the immu...Gene duplication allowed pigs to have more babies
...heir ancestors. These larger litters may well have helped the animals to survive the dramatic cooling of the earth that started during the Oligocene period, around 35 million years ago. Their investigations drew on the geological and palaeontological records, and used techniques from evolutionary biology,...Infants sighs may 'reset' breathing regulation mechanism as well as help lungs develop
... if in addition to mechanical benefits, sighs also helped development of communications between the respiratory control center, a specialized group of cells in the brainstem, and the lungs themselves. They studied 25 healthy one-month-old infants during quiet sleep, while they were either lying i......fornia, USA) agrees that the medical community has helped weave a web of misinformation about the alleged dangers of spiders. He concludes: "Instead of using the presumptive diagnosis of spider bite when the causative agent is unknown, physicians should diagnose idiopathic [of unknown cause] necrotic ulcer,...Bad news for pathogenic bacteria: Scientists find protein essential for bacterial survival
... researchers could at last determine just how DksA helped ppGpp hold fast to its target, RNA polymerase. DksA uses something scientists call the "backdoor of gene expression," a cavity on the RNA polymerase molecule called the secondary channel. DksA squeezes through this narrow tunnel toward the site whe...Study explains spatial orientation differences between sexes
...ugh instructions to pay attention to internal cues helped women to point the laser significantly closer to their straight-ahead, there were still significant differences between the sexes, with women tending to look more towards their feet. However, although women are more likely than males to misjudge what...Commercialization deal boosts hope for new sickle-cell drug
...loping a new drug. A private biotechnology company helped Dr. Brugnara and Dr. Jose Halperin (of Harvard Medical School) generate and test nearly 500 novel compounds based on the structure of clotrimazole, omitting the portion of the molecule that causes toxicity. One of these compounds was ten times more a...Warmer weather, human disturbances interact to change forests
...ery important role in shaping forests. "Harvesting helped create the forests we know today, and will continue to be a primary driver of change," he says. "If the climate changes, harvesting may provide opportunities for southern species to take hold in northern forests." However, there is a natural lag betw...Ottawa's leadership in biomedical and health research has paid off
...ent of being on the leading edge and this has also helped to attract and retain the best people." Biomedical and health research and innovation are fundamental to the health of Canadians for the development of new technologies and treatments. They are also key components of the knowledge based societies/eco...Save the rainforest - eat a tree
...ready. Mesones started an environmental group that helped stop the land grab. Fine says tropical rainforests are known for biodiversity, with about 10,000 tree species in the Amazon compared with 500 to 600 in North America's temperate zone. Yet the tropics really aren't different than ot...Double-segment periodicity underlies 'odd' segment generation in centipedes
...opmental "rule" followed by centipedes and thereby helped to solve a well-known evolutionary puzzle. Centipedes are a familiar group of arthropods characterized by a long body made up of individual segments, each with its own pair of legs. Despite their familiarity, they actually represent a developmental m...Geologists discover water cuts through rock at surprising speed
...d sediments at the earth's surface. These analyses helped them gauge when the rivers abandoned their ancient beds and, consequently, exposed bare rock surfaces, known as terraces, where people climb and hike today. Knowing the age of each river terrace and its height above its current river bed, they were a......ons with their child. We found that living at home helped teenage mothers stay in school during the first two years of their babies' lives but had little effect on their parenting. In contrast to our study, prior research had found that young mothers who lived at home were less skilled as parents. Our find...