Tag: "helper" at biology news
Preschool bolsters early childhood immunity, reduces risk of young adult Hodgkin's lymphoma
...irth," she said, "infants are skewed toward type 2 helper
T-cell immunity or Th2 which is characterized by the B-cell antibody-mediated response to infections by parasites, helminths or nematodes. "In contrast, the phagocyte-dependent, inflammatory Th1 immune response matures with age, and does so in re...
Harmless virus helps slow HIV by boosting immune proteins
...ke HIV, it infects white blood cells-specifically, helper
T cells. It is also contracted in the same way as HIV-through bodily fluids. About 10 to 15 percent of healthy blood donors either have active GBV-C infection or antibodies indicating past exposure. Almost 90 percent of people with HIV, according to ...
Yale researchers discover new potential asthma therapeutic targets related to parasites and insects
...cialized lymphocytes (white blood cells), called T helper
type 2 cells. Other cell types promote different kinds of inflammation in which the AMCase protein is not made in high amounts. If this protein is blocked, it will only alter asthmatic type inflammation, but not the other types of inflammation, which...
RNA inner workings partly unveiled in Stanford study
...called transcription. Along with more than a dozen helper
molecules, RNA polymerase determines which protein...us on the middle layer, which contains many of the helper
molecules. To see the structure of the protein layers, the group passed extremely bright X-rays - ...
Scripps scientists say genetic mutation doesn't protect against HIV and plague
...at inserts into the cell membranes of human CD4+ T helper
cells. HIV particles use CCR5 to gain entry into CD4+ T cells. The CCR5 32 mutation -- a deletion of 32 bases of DNA from the CCR5 gene -- was first identified in 1996 in individuals who seemed to be protected from infection with HIV despite having ...
JCI table of contents, January 2, 2004
...that is formed by CD8+ human CTLs, but not by CD4+ helper
T cells, before foreign antigen complexes are reco...latory mechanisms in CTLs that are not shared with helper
T cells. TITLE: Cytotoxic T lymphocytes form an antigen-independent ring junction AUTHOR CONTACT: M...
Linking the immune system with lipid metabolism
...on-gamma and interleukin-4, which in turn activate helper
T cells. The helper
T cells then induce specific B cells to unload bursts of soluble antibodies into the bloodstream, an...
Scientists develop a novel strategy to help prevent transplant rejection
...eased cells. There are two key types of T cells: T helper
cells, which stimulate immune response, and T supp...r cells, and provoke a corresponding decrease in T helper
cells," says Professor Dallman. "The key role that T suppressor cells play in preventing organ rejec...
Lasker Award honors Rockefeller University biochemist for pioneering studies of gene activation
...; identification of these enzymes' associated helper
factors, called the general transcription machinery; and definition of the first of many hundreds of DNA-binding regulatory proteins, called activators and repressors, that control the rate of gene transcription. These three advances could no...
Human genes can predict AIDS progression rate
...rganism. Since the AIDS virus attacks and destroys helper
T-cells in humans - thereby limiting and eventually destroying a patient's ability to stop the virus from replicating - the number of T-cells within an individual person is an indicator of the progression of the disease; the fewer the T-cells, the gr...
Towards an AIDS vaccine: unusual antibody that targets HIV described by scientists at TSRI
... by binding to, entering and ultimately, killing T helper
cells, immune cells that are necessary to fight of...and other pathogens. As HIV depletes the body of T helper
cells, common pathogens can become potentially lethal. The latest statistics are grim. The World Hea...
New research establishes genetic associations in hepatitis C
...illion worldwide. Background An imbalance in helper
T-cell type-1 (Th1) and type-2 (Th2) cytokines has been suggested as playing an important role in the cause of chronic viral infections, but this issue is not resolved in patients with hepatitis C virus (HCV) infection. Inflammation of the portal and...
Bodys own antibodies may drive new strains of HIV
...o, HIV infects and disables the very immune cells, helper
T cells, which are supposed to mobilize the immune system against the virus. Richman's study is the first to track in detail how the virus outpaces the antibody response over time. Since 1987, researchers have studied about 60 potential HIV vaccines...
Revealed: How a master protein remodels chromosomes to orchestrate gene expression
...foreign organisms and diseased cells directly, and helper
T cells, which emit proteins like interleukin 2 th...winnowed as they mature into "single positive" CD4 helper
T cells or CD8 killer T cells. Early in 2000, Kohwi-Shigematsu and her coworkers reported studies u...
HIV selectively suppresses anti-HIV defense cells
...e May 2 issue of Nature. CD4+ T cells, also called helper
T cells, are HIVs primary target. These cells help...duals, the researchers isolated three subgroups of helper
T cells: HIV-fighting cells, cytomegalovirus-fighting cells, and a mixed group. The scientists then ...
Keeping autoimmunity in check may depend on balance in the immune system
... their activity depends on receiving "help" from T helper
cells that also become stimulated when an infectio...egulatory T cell, may be important in preventing T helper
cells from activating B cells with the potential to generate self-reactive antibodies. Under normal...
Stanford researchers uncover possible approach to attack HIV-infected cells
...articular class of white blood cells known as CD4+ helper
T cells. These cells coordinate the body's defense...ow doses of Gd-Tex that were fatal to HIV-infected helper
T cells. The drug's effectiveness for HIV treatment remains an open question, and the Stanfor...
DNA arrays give clues to better vaccines
...tivating another arm of the immune system called T helper
responses and is critical for host resistance to tuberculosis infection in mice and humans. The lack of strong IL-12 response in macrophages indicates that this may be one way M. tuberculosis evades host defenses and supports the use of both IL-12 a...
Development of important immune cells relies on more complicated influences than scientist had thought
...rs have overturned existing scientific belief that helper
T cells are programmed to differentiate only by outside signals. Instead, the researchers have shown that Th1 and Th2 cells -- which are involved in inflammatory and allergic responses, respectively -- develop in a delicate chronological pattern, a...
Chemokines in allergic asthma
The recognition of two major classes of helper
T cells, Th1 and Th2, has focused attention on the distinctive sets of cytokines produced by these cells and on their role in activating or suppressing inflammatory responses. More recently, it has become clear that Th1 and Th2 cells also differ with...
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