Researchers Take Major Step Toward Cracking Ebola Code
...t now appears sGP actually binds toneutrophils and hinders an early inflammatory response that might stop the virusfrom replicating. The second part of the glycoprotein 1-2 punch comes from the transmembraneversion of GP. This version attaches to endothelial cells, possibly clearingthe way for the Ebola vir...... crystallization, which considerably delays and hinders determination of co-crystal structures of factor Xa with specific inhibitors, this particular hybrid was chosen as a potential first step in the engineering of a model for fXa-inhibitor interactions with crystallization properties more li...Rutgers scientists help uncover protein implicated in multiple sclerosis
...ut why the protein, osteopontin, helps rather than hinders MS could ultimately help scientists learn how to block MS, which damages communication among the brain's nerve cells by attacking the fatty myelin sheath that coats them. The research was reported in the Nov. 23, 2001 issue of the magazine Science. ...Compounds prevent alcohol's disruption of important developmental process
...verages--interferes with L1 adhesion molecules and hinders these crucial cell-to-cell attachments. They have also shown that octanol and other non-beverage alcohol molecules block ethanol's ability to disrupt L1 molecules and can prevent fetal damage from ethanol in mouse embryos. In another recent study, Ca...Stanford biomedical ethicist speaks on role of race in scientific research
...mentally misrepresents human genetic variation and hinders research." The symposium will examine these two positions in the context of current scientific studies of human genetic variation - including haplotype mapping, genetic clustering methods and pharmacogenetic studies - and will discuss these studies' ...JCI table of contents, July 15, 2003
...ted applications of low doses of contact allergens hinders the development of the allergic reaction. They demonstrate that mice lacking IL-10 cannot achieve LZT to allergens, suggesting that this IL-10driven response may be utilized in allergic therapies. TITLE: Critical role of IL-10 in the induction of low...Smallpox in Europe selected for genetic mutation that confers resistance to HIV infection
...les. They thus produce fewer CCR5 receptors, which hinders initial infection by HIV-1 and slows spread within the body once an immune cell has been infected. Those lacking both alleles produce no CCR5 receptor. Based on a population genetics model, Galvani and Montgomery Slatkin, a UC Berkeley professor of i...Vascular access vital to pump up tissue engineering
...his physiological issue, another major factor that hinders acceptance of breakthrough technologies of tissue engineering as standards of practice is the reluctance of the medical community to accept them. Physicians and surgeons are often traditionalists, and unless they approve of and use them, the products...Hemochromatosis, inflammation and anemia
...tion. "Unfortunately, while this decrease in iron hinders the spread of parasites and is beneficial in the short term, it can cause anemia," notes EMBL Group Leader Matthias Hentze. "During a long term inflammatory condition, low levels of iron can starve the bone marrow of this metal which is essential for...Images of 'tail' of protein needed for cell multiplication suggest anticancer drug targets
...howed that deleting the tail from E2 significantly hinders the ability of E2 to transfer NEDD8 to Cul1, and blocks its ability to drive cell proliferation. This demonstrated the important role played by this unique protein. In addition, using X-ray crystallography techniques, Schulman crystallized samples o...