Tag: "hippocampus" at biology news

Memory mechanism found at nerve cell connections in the brain

... Huber and colleagues worked with tissue from the hippocampus region of the brain, separating synapses from their cell bodies. Even after the cells and synapses were cut apart, the synapses continued to be modified by local protein activity, indicating that synaptically synthesized prote...

Pay attention to potassium channels! First steps in the molecular identification of SK channels and their role in neuronal signal encoding.

...he frequency encoding of signals in neurons of the hippocampus (Proc. Natl. Acad. Sci. USA. 96: 4662-4667, 1999). Together with a detailed mapping of the expression of calcium-activated potassium channels (SK channels) in the brain (Mol. Cell. Neurosci., ACADEMIC PRESS), their findings contribute to our understa...

Rat study shows high-fat diet impairs concentration and memory

...y on one part of the brain - the hippocampus." The hippocampus is located near the centre of the brain and is critical for normal memory function. It enables us to register new memories and recall those memories after a period of time. In the study, young adult rats were divided into three dietary groups -- thos...

Brain researchers from UCLA, Johns Hopkins discover role of key protein in converting short-term memories into lifelong ones

...ch like writing data to a computer hard drive, the hippocampus interacts with the cerebral cortex. If problems occur in either the hippocampus or cortex, however, memory impairment can result. To better understand this process, Frankland and h...

Dopamine-dampening gene linked to prefrontal inefficiency, schizophrenia

...r example, they are studying a gene in the brain's hippocampus that, together with COMT, could boost schizophrenia risk three-fold. Although it's not yet known exactly how the COMT val variant impairs prefrontal efficiency, evidence suggests that by reducing dopamine it reduces signal-to-noise ratios of communi...

Gene therapy restores feeding behavior to starving mice

...accumbens in mediating reward, and its role in the hippocampus in learning and memory. The motor coordination of the mice treated in either brain region did not appear to improve very much following gene therapy. The treated mice were still slow to initiate movement and had poor coordination. This indicated...

Pattern in protein manufacture found in hippocampus

...." Job and Eberwine grew particular cells from the hippocampus called neurons that extend long structures (dendrites) away from the main portion of the cell, known as the cell body. Cell bodies store the genetic code (the DNA) so a message, mRNA, which is made from the DNA, moves from the cell body to dendrites....

Abstinence may make the brain grow stronger

...o cerebral hemispheres, the anterior aspect of the hippocampus and the mammillary bodies, brain structures that engage in consolidation of new memories, and the cerebellum, the 'little brain' that is critical to postural stability, motor timing, and motor learning as well as certain components of cognitive funct...

Alcohol consumption during pregnancy alters thyroid function

...lcohol exposure both affect the development of the hippocampus and the cerebellum." Knowing these similarities, the study authors investigated if ARBDs are, in part, a result of alcohol-mediated thyroid hormone system dysfunction. Researchers gave pregnant ewes alcohol doses of 0.75, 1.25, 1.5 or 1.75 g/kg or s...

Preventing overload in the brain

...of Amsterdam carried out their observations on the hippocampus of rats. The hippocampus probably plays an important role in converting the short-term memory to the long-term memory. The h...

Neural stem cells move to damaged areas of brain after injury

...o generates neuroblasts, which form neurons in the hippocampus -- the section of the brain involved in learning, ...idespread, diffuse damage to neurons in the brains hippocampus and other parts of the limbic system -- according to Parent, who specializes in epilepsy research. W...

Office of Naval Research awards $8.4M to young investigators

... University of Pennsylvania will develop a silicon hippocampus based on the method of transforming the brains cel...analog-digital microelectronic chips. The silicon hippocampus will exhibit associative memory, episodic memory, and spatial maps that emulate the information carr...

Brain's cleaning crew may aid learning, memory formation

...han100 percent in a region of the brain called the hippocampus 30 minutes after the onset of long-term potentiati...They then examined the transporters in the animals hippocampus region. The way you know that the animal remembers what youve done is because its behavior has chang...

Researchers develop blood test to diagnose Alzheimers-type changes in mice

...wo key regions involved in Alzheimers disease: the hippocampus and the cingulate cortex. Before m266 injection, the amount of Ab in the animals blood did not correlate to the number of plaques in their brains. But within five minutes of m266 injection, Ab levels increased dramatically and did correlate with th...

USF neuroscientists study potential of cord blood cells to rescue aging brain

...C-derived cells into the subventricular region and hippocampus of the rodents' brains. These are the two areas of the brain where new neurons and glia are regenerated throughout life. Whether HUCB-derived cells transplanted directly into the brains of aging rats can reverse or slow age-related declines in lea...

First live studies of important cell structures may shed light on Alzheimer's, other diseases

...odies have been found by autopsy most often in the hippocampus region of the brain, though the bodies are not restricted to neurons. Still, the bodies appear to have some association with a wide range of diseases, including those mentioned earlier, along with ataxic Creutzfeldt-Jakob disease and Pick's disease (...

Alzheimer's, other diseases, may benefit from first live studies of key cell structures

...odies have been found by autopsy most often in the hippocampus region of the brain, though the bodies are not restricted to neurons. Still, the bodies appear to have some association with a wide range of diseases, including ataxic Creutzfeldt-Jakob disease, Pick's disease (both neurodegenerative disorders) and ...

Gene may link alcohol drinking and stress, mouse study suggests in Science

...ing properties of alcohol come from here. And, the hippocampus is important for memory and environmental conditioning. While the details aren't clear yet, Spanagel's team thinks that stress causes neurons to express more NR2B subunits, which are alcohol sensitive. Spanagel isn't sure why it took three weeks for...

Astrocytes play starring role in neural stem cell development

...prising to us that the stained stem cells from the hippocampus would only produce neurons when grown on glia from the hippocampus, but they hardly made any neurons at all when we grew them on glia from the spinal cord," said Stevens. "While it is only speculation at this point, it may be that spinal cords fail ...

The pathway to anxiety begins early in life

...hat certain types of anxiety may be located in the hippocampus and the cortex of the mouse brain. Then they determined what happened if they shut off activity of the serotonin receptor at different times in the mouses life. Mice without the receptor between five and 21 days after birth, become very anxious as ad...

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