Newly discovered cellular process helps cells respond to DNA damage
...1 and p53 following DNA damage. The scientists are hopeful that they can use this information to improve therapy for many types of tumors. "Because ATM is central to a cell's response to irradiation, blocking its activation or activity might make virtually any type of tumor much more sensitive to radiation ...Rare Asian dolphin threatened by human activities
... to drive fish into range of throw nets. Smith is hopeful that the dolphin's popularity and value to fishermen as a living resource will facilitate a site-based conservation program that would work to eliminate threats and promote cultural traditions that would benefit the dolphins. "Local throw-net fisherm...Americans deeply divided about use of genetic technologies in reproduction
...shington, DC, December 9, 2002 -Americans are both hopeful and fearful about the rapidly advancing power of scientists to manipulate human reproduction, according to a new survey released today by the Genetics and Public Policy Center, a Johns Hopkins University effort funded by The Pew Charitable Trusts. ...A pathway towards cures for Parkinson's and cancer
...s to find out how they worked in living organisms, hopeful that this would give them further understanding of the Hedgehog signalling pathway. They found their small molecules were interacting with a poorly understood protein that is found on the surface of developing cells. This protein, called Smoothened, ...Parasite, mosquito genomes complete malaria picture
...mosquitoes and humans, notes Dr. Gottlieb. "We are hopeful that this wealth of information will translate into new drugs, vaccines, and insecticides that will more effectively control malaria and, ultimately, lift a burden of suffering from millions," he adds....Purdue creates self-generating nanotubes with 'dial-up' properties
..., biosensors and drug delivery systems. Fenniri is hopeful the findings will prove beneficial in many fields. "Nanotechnology relies on our ability to control the behavior of matter at the molecular scale," he said. "The versatility and robustness of our system is already pointing the way towards numerous a...New study expands look at high-dose vitamin D with docetaxel for advanced prostate cancer patients
... have few treatment options, and we are cautiously hopeful that this study will further confirm and extend the promising results we've already seen with docetaxel in combination with high-dose pulse administration (HDPA) calcitriol," said OHSU Cancer Institute oncologist Tomasz Beer, M.D., study chairman and...Gene therapy treats first disease affecting multiple organ systems in a large animal
...y and biophysics at Washington University. "We're hopeful that the approach might also be applicable to hemophilia." Lysosomal storage diseases such as MPS VII can be treated through enzyme replacement therapy, but that approach requires regular intravenous injections and is prohibitively expensive. Bone-m...Researchers identify defect that causes rare muscular dystrophies
...t component of learning and memory, so Campbell is hopeful that his teams studies will improve understanding of possible links between muscle physiology and neurobiology. In the two articles, Campbell and his colleagues describe experiments that demonstrate that dystroglycan is defective in muscle-eye-brai...Researchers develop mouse model of Rett syndrome
... will allow us to ask these questions." Zoghbi is hopeful that studying the mouse model will also have implications for treatment of patients diagnosed with Rett Syndrome. "As development progresses, what we encounter -- our experiences -- may also change how the brain responds. This may account for indiv...MIT technique could improve cartilage repair
...ed each year in the United States. The MIT team is hopeful that the "cartilage gel" could be implanted arthroscopically, through a small external incision. Such minimally invasive surgery is not only less expensive, but "reduces the recovery time for the patient," Grodzinsky said. In 1993, Zhang discovered t...Clonal human (hNT) neurons re-establish connection in rats with severe spinal cord injury
... reconnected spinal cords can walk again. "We are hopeful that our work with hNT neurons in an animal model for spinal cord injury will ultimately lead to the first transplant of human neural progenitor cells to treat spinal cord injury in humans," said neuroscientist Paul R. Sanberg, PhD, DSc, director of ...Common bacteria kills elkhorn coral off Florida keys, says UGA research team
.... "Despite the trends in our data, we still remain hopeful that the surviving coral will repopulate the reef. We must maintain the highest possible water quality standards in the Florida Keys. These coral reefs are so beautiful and so important. We must do our best to protect them." The EPA and the State of ...Mosquitoes repelled by tomato-based substance
...the approval process will take, Bennett said he is hopeful IBI-246 will win EPA approval by the end of the year....Protein causes muscle wasting syndrome in mice
...ons. "Based on what we know about myostatin, we're hopeful that it's involved, but we have no direct evidence of that yet," says Lee. "Regardless, treating cachexia still would not treat the underlying condition -- cancer, AIDS or what-have-you," notes Lee. "But because cachexia is the direct cause of death...CF Foundation seizes proteomics for drug discovery
...f the CF Foundation and CFFTI. We are particularly hopeful about the potential of this technology because it offers the possibility of discovering drugs to intervene at the root of the disease. Recently, automation of established methods to analyze proteins has made the technology more rapid and comprehensiv...Study suggests mechanism for heart defect that kills young athletes
... survive, says Sehnert. Still, the researchers are hopeful that the new finding can contribute to future gene therapy strategies that might allow only the normally functioning gene to be expressed, thereby sparing people the potential devastation of the genetic condition....... how protein signaling affects cancer, we are very hopeful that this exciting new technology will aid us in elucidating the structures of proteins and other molecules," said Dr. Andrew C. von Eschenbach, NCI director. X-ray crystallographers determine the three-dimensional shape of a molecule by blasting a b......y, and ultimately maybe even less than an hour. Im hopeful that in a few years well be able to do this," she says. Within each living cell are long strands of DNA, the genetic code containing all the information to create and control every cell in an organism. DNA resembles a long spiraling ladder, and the ......r settlement has been defined, and researchers are hopeful that similar rules may apply to east- and south-coast lobsters - though at the moment, the determining conditions are a complete mystery, says Dr Griffin. "We believe that variations in lobster settlement are best explained by changes in conditions i...