Researchers develop fast track way to discover how cells are regulated
... the worm genome is comprised of 20,000 genes. The human genome has over 30,000 genes. "When you look at the numbers, it becomes very clear that the old way -- studying one gene at a time -- is too slow. It becomes a problem of scale, with high throughput the only answer." Mango's team used a unique proc...USC study links historical increases in life span to lower childhood exposure to infection
...ns firmly link this gradual yet steady increase in human life span to lower childhood rates of exposure to infectious diseases such as tuberculosis and malaria. The key to their theory lies in one word: inflammation. Infectious diseases cause chronic inflammation in the blood that, decades later, le...Washington University in St. Louis leads group studying aging process
...n the aging process in everything from bacteria to human beings. Himadri Pakrasi, Ph.D., Washington Univers...in from plants may well transcend plant biology to human biology," said Pakrasi. "Plants make all sorts of vitamins, the antioxidant ones, A and E, to prote...Wiley publishes Welcome to the Genome: A User's Guide to the Genetic Past, Present, and Future
...past discoveries that led to the sequencing of the human genome, presents genomics challenges facing today's scientists as well as society in general, and outlines future possibilities of the developing genome era. Social issues, particularly questions of ethics, receive special attention, covering an imp...Brain has center for detecting sound motion
...processing abilities were impaired, and animal and human neuroimaging studies had not been able to conclusively tease apart the two abilities. Ducommun and her colleagues discovered the region by studying a woman who was to be operated on to alleviate intractable temporal lobe epilepsy. The operation would...JCI table of contents September 15, 2004
...m Tactics to Vet Complex Disease A whole range of human muscular and neuromuscular diseases, are caused by... Scripps Research Institute, transplanted mouse or human adult bone-marrowderived stem cells in the retinal nuclear layers of two different mouse models for ...9/11 search-and-rescue dogs exhibit few effects from exposure to disaster sites
...1 dogs is heartening, both for the animals and the human rescue workers," said lead researcher Cynthia M. O...pidly than humans, they can serve as sentinels for human disease. We are encouraged that we do not see significant increases in cancer and respiratory disea...New fruitfly model of diabetes has future implications for pancreatic cell transplantation
...the unexpected similarities between the insect and human pancreas, Rulifson explains that now the fly can s...ding of this process will help guide screening the human genome for genes that have a similar function in how alpha and beta cells develop. "This will ...Human chromosome 5 final sequence analysis released to public
... years after publicly revealing the official draft human genetic sequence, researchers have reached the hal... powerful tool for scientists trying to understand human disease," said Secretary of Energy Spencer Abraham. "I'm pleased that the Department of Energy, whi...Ecology of infectious diseases grants awarded
...gical mechanisms that govern relationships between human -induced environmental changes and the emergence a...ast 20 years, unprecedented rates of change in non human biodiversity have coincided with the emergence and re emergence of numerous infectious diseases arou...Venn diagram tactics to vet complex disease
A whole range of human muscular and neuromuscular diseases are caused by mutations in the mitochondrial respiratory chain/oxidative phosphorylation system. The problem is that there are about 120 genes involved in this system, some that are found in the mitochondria, and ...Protein is key to fatal disorder and normal cell function
...irst to identify where the cln3 protein resides in human brain cells and to link the protein's location to ...used her investigation of the protein primarily on human and rat brain cells because most of the disease's effects occur in the brain. She also studied cultu...Simian virus 40 not associated with non-Hodgkin lymphoma, study shows
... Institute. SV40 has been suggested as a cause of human cancers, including NHL. In the United States betwe...ecent evidence has suggested that it cannot infect human lymphocytes. Moreover, epidemiologic studies have failed to find an increase in the risk of NHL amon...Pioneering AIDS researcher to speak at UH
...out a DNA vaccine that has already reached phase-I human trial, as well as discuss two more vaccines under development. These vaccines under development are based on a viral strain common in Chinas southwest region. The China AIDS Initiative, a consortium of Chinese and American organizations that have c...Research on carbohydrate metabolism receives historical recognition
Research by Carl and Gerty Cori exploring how the human body metabolizes glucose will be designated a National Historic Chemical Landmark in a special ceremony at the Washington University School of Medicine in St. Louis on Sept. 21. The American Chemical Society, the world's largest scientific society, s...First glimpse of DNA binding to viral enzyme
...omised immune systems, such as those infected with human immunodeficiency virus (HIV), an opportunistic adenovirus infection can be deadly. During infection, adenovirus makes an enzyme called a protease, which cleaves or degrades viral "scaffolding" proteins to complete the maturation of newly synthe...IBD (Crohn's, Colitis) 'joins' cancer, inflammatory diseases in associated blood vessel growth
...scopy, and in vitro by flow cytometric analysis of human intestinal microvascular endothelial cells (HIMEC) activated by bFGF, VEGF and TNF-. Pro-angiogenic bioactivity of mucosal extracts was tested in vitro by induction of HIMEC migration (cells/field) and in vivo by the mouse corneal angiogenesis assay....Tufts University establishes $4 million dollar tissue engineering resource center
...f the core projects, such as tissue engineering of human ligaments using transfected adult stem cells. In 2003, Kaplan and a former post doctoral student discovered that spiders and silkworms are able to spin webs and cocoons made of incredibly strong fibers because of the way they control water c...Researchers identify distinctive signature for metastatic prostate cancer
...edgehog pathway was, indeed, active in cultures of human metastatic prostate cancer cell lines. Blocking He...n done before, to my knowledge to cause a primary human cell to become a cancer," said Beachy. "And that suggests that perhaps we have identified the right ...Sugar-coated sea urchin eggs could have sweet implications for human fertility
...ls, including the potential to solve some baffling human reproductive problems. "The importance for people...derstanding, she said, could lead to solutions for human reproductive problems, including new approaches to contraception. The research also opens the possi...