Murine model of human hyperinsulinism
...odel of human familial hyperinsulinism. Familial hyperinsulinism (HI) is a rare inherited disorder that results from the unregulated release of insulin by pancreatic b cells. As published in G&D, researchers from UPENN Medical Center have generated a strain of mice in which the gene Foxa2 is specifically deleted i...Novel test pinpoints location of rare insulin disorder to guide surgical cure in newborns
...rol in newborns with a condition called congenital hyperinsulinism (HI), irreversible brain damage may result. Medica.... Stanley on the recent study. Further work by the hyperinsulinism team will focus on devising more effective treatments for the diffuse form of HI, which currently re...