JCI table of contents September 15, 2004
...e TITLE: Decreased susceptibility to renovascular hypertension in mice lacking the prostaglandin I2 receptor IP AUTHOR CONTACT: Fumitaka Ushikubi Asahikawa Medical College, Midorigaoka Higashi 2-1-1-1, Asahikawa 078-8510, Japan Phone: 81-166-68-2362; Fax: 81-166-68-2369; E-mail: ushikubi@asahikawa-med.ac.jp Vi...APS awards more than $140,000 to minority students of physiology
...Her research will give insight on the mechanism of hypertension due to high levels of salt. Jessica Clark University of Arizona The focus of Ms. Clark's research is epidermal growth factor (EGF) and its role in protecting the intestine against a disease that affects premature babies, called necrotizing enteroc...JCI table of contents, 16 August, 2004
...ype mice. When the mice were given a high-Na diet, hypertension worsened, but they additionally had excessive weig...cting ductspecific knockout of endothelin-1 causes hypertension and sodium retention AUTHOR CONTACT: Donald E. Kohan University of Utah Health Sciences Center, Sa...LBP-1a gene mutation linked to disruption of normal fetal development
... abnormal condition during pregnancy that triggers hypertension and fluid retention in the mother and can lead to the more severe condition of eclampsia, which causes convulsions and coma. Missed abortion refers to a pregnancy in which the embryo stops developing normally, and which usually ends in spontaneous ab...Reading hexametric rhyme supports cardiac synchronization, especially after a heart attack
...of cardiovascular diseases, especially no hypo- or hypertension or anti-arrhythmical therapy. All subjects were invited individually three times to the therapy center at the same time of day. In each of the three sessions the subjects performed a different exercise (in random order): hexameter recitation (...JCI Table of Contents, 15 July 2004
...buckling lipodystrophy from insulin resistance and hypertension AUTHOR CONTACT: Robert A. Hegele Robarts Research Institute, 406-100 Perth Drive, London, Ontario N6A 5K8, Canada. Phone: 519-663-3461: Fax: 519-663-3037; E-mail: hegele@robarts.ca View the PDF of this article at: https://www.the-jci.org/press/...Vioxx in high doses causes hypertension
...y underestimate the drug's ability to cause edema, hypertension and heart failure, she added. Of the TennCare patients in the Vanderbilt study who were receiving over 25 milligrams of Vioxx a day, 15 percent had been treated for congestive heart failure during the previous 12 months, and 22 percent had been treat...New pulmonary hypertension guideline challenges use of common medication
...ew evidence-based guideline for pulmonary arterial hypertension (PAH) cautions the use of calcium channel blockers...sand new cases are diagnosed each year. Pulmonary hypertension can develop in patients of all ages and ethnic groups, and both genders; however, women ages 20 to 4...Gene therapy alternative to calcium channel blockers
... of heart diseases, including angina, arrhythmias, hypertension and enlarged heart. Their findings published in the latest edition of Circulation Research, online July 8 may lead to a gene therapy alternative to calcium channel blockers and their sometimes severe side effects, but also further interest in the...Endurance exercise found to be equally effective as diuretics in improving cardiac health
...rged heart, is commonly observed in a patient with hypertension and can be a powerful predictor of heart failure i...or cycling, has been recommended for management of hypertension because it is effective in reducing blood pressure. Recent studies have shown that exercise training...Obesity and hypertension: Two epidemics or one?
...tes and hypertension. The link between obesity and hypertension is well known, but the exact nature of the associa...ut the strength of the association of obesity with hypertension varies among different racial and ethnic groups. Generally, risk estimates suggest that approximatel...Fox Chase discovery may help physicians diagnose, treat devastating childhood disease
... a part in other major diseases, including cancer, hypertension and cardiovascular disorders. Research elsewhere has shown that inappropriate expression of EDNRB can promote cell proliferation and metastasis of tumors, including melanomas and breast and prostate cancer cells. Shin's laboratory has studies in pro...Inflammation, hypertension are focus of major new MCG research program
... that regulate inflammation and the big problem of hypertension is the focus of a major new research program at th...volved just in the end-organ injury that occurs in hypertension and have nothing to do with blood pressure regulation itself." So the researchers are dissecting the...Vanderbilt doctors use Viagra to treat infants with pulmonary hyptertension
...y have the power to save babies. Chronic pulmonary hypertension is virtually a death sentence in newborn babies. I...cently suggested that babies with deadly pulmonary hypertension may respond with good success to Sildenafil. In the case of 6-month-old Hartley Wilson, Don Moore, ...Researchers substitute whole chromosomes to speed the search for genes in common diseases
...hers know that most common human diseases, such as hypertension and diabetes, have a large genetic component. Many genes, interacting with the environment, contribute to these diseases. For researchers, a major challenge is finding all the genes involved with a particular disease. Researchers from Case Western ...UT Southwestern researchers reveal mechanisms of smooth-muscle contraction
...y have implications in treating conditions such as hypertension and other smooth muscle related conditions where there is too much contractile activity," said Dr. James Stull, chairman of physiology at UT Southwestern and senior author of the study. The research appears in an upcoming issue of the Proceeding......le in USA, and over 1 billion worldwide. Although hypertension weighs in heavily on world health, its underlying cause for the vast majority of cases is unknown. One of the known components involved in regulating blood pressure is the b1subunit of the large Ca2+ activated K+ (BK) channel. The beta1 subunit act...JCI table of contents, 2 April 2004
...le in USA, and over 1 billion worldwide. Although hypertension weighs in heavily on world health, its underlying ...nit is associated with low prevalence of diastolic hypertension AUTHOR CONTACT: Miguel A. Valverde Universitat Pompeu Fabra, Barcelona, Spain. Phone: 34-93-542-2832...UT Southwestern researchers identify gene as essential for vascular smooth muscle development
...velopment of novel therapeutics for disorders like hypertension and asthma. Their work appears in today's issue of Nature. Smooth muscle cells are essential for the formation and function of the cardiovascular system, as well as many internal organs such as the stomach, intestine, bladder and uterus. Abnormalitie......ations in transcription factors, including cancer, hypertension and immunological and neurological disorders. Discovering how transcription factors regulate genes in various human organs should continue to provide clues to the causes of disease and offer new approaches for therapy."...