OHSU researchers discover molecular signaling system controlling aspects of embryonic development
...eloping new drugs. "Receptor and signal pairs are ideal targets for medicines because this is where human biology gets very specific. Identifying the players allows us to design drugs targeted at a precise molecular interaction. These types of drugs tend to have the maximum therapeutic impact with the few...Unfaithful songbirds increase offspring fitness
...peration and were therefore seen as reflecting the ideal of monogamous partnership. This view has changed dramatically over the last decade: since molecular 'fingerprinting' techniques became available, behavioural ecologists have routinely used paternity analyses to study mating systems. We now know that...Antarctic penguins thrive in ocean 'oases'
...f the ocean with added sunlight, so polynyas offer ideal conditions for phytoplankton blooms. Because the ice around polynyas is thin in the early spring when the long Austral day begins, they are the first areas to get strong sunlight. The open waters retain more heat, further thinning ice cover and leadi...DuPont and NREL to develop world's first integrated 'bio-refinery'
...both DuPont and NREL creates what we believe is an ideal partnership." Doug Kaempf, program manager of the Office of the Biomass Program within the U.S. Department of Energy (DOE), said partnerships between industry and the U.S. government's national laboratories are essential to catalyze the emergence of ...Purdue researchers solve decades-old corn, sorghum problem
...ut into widespread cultivation because it displays ideal crop characteristics, such as increased grain yield and improved stalk strength and quality, Johal said. Johal and his colleagues found that loss of a gene product called a p-glycoprotein generates these dwarf corn and sorghum plants by interfering w...New findings in yeast may reveal why growing older is the greatest carcinogen in humans
...isiae, a simple, single-celled organism, may be an ideal model for understanding the complexities of age-related cancer development in humans. "Yeast gives us, for the first time, the potential for not only understanding the principles of what's going on mechanistically but also which molecules might be re...Discovery may be first plant cell surface molecule that halts cell proliferation
...nce in 2000, the first for a higher plant, made it ideal for molecular investigation such as this. In addition, this small weed has homologues or counterparts of many important human proteins, including some involved in diseases, such as cystic fibrosis and cancer. "We have identified the first and a truly...Fruit fly pheromone receptor first ever discovered linked to specific sexual behavior
...added, flies' simpler nervous system makes them an ideal model for study. Courtship in Drosophila includes a regular sequence of behaviors, which are critical for mating, Amrein explained. First, a male identifies a female visually. The male then approaches the female and touches her with his forelegs -- w...Fishing for photos of rare or unknown deep-sea creatures with an electronic jellyfish lure
...n and study of the oceans, but also from less than ideal traditional research methods. Deep-towed nets can shred animals like jellyfish or damage captured animals to the point that their natural behaviors cannot be observed in the lab. Manned submersibles and remotely operated vehicles (ROVs) can deliver h...SUCCESS 2002 Student Contest award ceremony
... (i.e. collagen synthesis, differentiation) in the ideal weightlessness conditions of the International Space Station. Understanding the molecular mechanisms of the reduced functionality of osteoblasts could lead to new treatments for bone mass loss due to long-term stays in space and for osteoporosis on E...New guidelines can help health officials better predict and control dengue epidemics
...ged the proliferation of water containers that are ideal larval habitats for Aedes aegypti, the mosquito responsible for epidemic dengue transmission. Efforts to avoid large-scale epidemics have focused on engaging communities in reducing the mosquito's density by emptying, cleaning, treating, and removing...Distinctive advantages give optical sensors the edge over conventional systems
...c interference. These characteristics make them an ideal choice as temperature sensors in many applications. Scientists have been working on a fiber-optic sensor that measures temperature using a reflector, which can be used in industrial power plants, nuclear plant, aircrafts, and ships. "Researchers are ...Learning opportunities expand using GIS data
...ion or approximately 1 km resolution, the data are ideal for educators, researchers, government officials, the private sector, and the general public for conducting regional-scale customized analyses. The Global GIS Digital Atlas consists of one DVD-ROM with the entire data set or seven regional CD-ROMs, a...On tap: Genomic sequence of an enemy of beer and bread
... cool, wet weather of the U.S. Midwest provides an ideal environment for the fungus to take hold. The result:: fields of blight, identified by withered, bleached heads of grain. At harvest, many of the grains are shrunken and white, and harbor the mycotoxins. "Classical control methods for blight just aren...Von Liebig Center awards funding to six projects to commercialize UCSD faculty research
...ult codec for image transmission -- JPEG -- is not ideal for wireless because it does not take advantage of temporal redundancy using motion estimation and prediction. The result: the decoded image is degraded significantly. As part of this project, Professor Nguyen will develop the prototype for an effic...Protein holds promise as new diabetes drug target
...s solidified the view that glucokinase would be an ideal target for an antidiabetic drug, Magnuson said. Even so, he added, "no one ever thought we would find a drug that directly targets the enzyme and activates it." The investigators at Hoffman-La Roche were actually screening for compounds that would w...Researchers zero in on new drug combination strategy
...ing method cannot determine if a combination is an ideal fit for use in patients, it enables researchers to make more informed decisions about which drugs to advance into expensive clinical trials. The process ultimately streamlines the "match-making" phase of starting a new chemical relationship, delving ...Obese mice provide clues to a natural system that puts brakes on obesity
...ulin sensitivity," Stoffel continues. "This is the ideal combination for pharmacologically treating obese or type 2 diabetic patients, or people with a risk of developing obesity." Foxa-2 was originally discovered in the 1980s by Rockefeller scientist James E. Darnell Jr., M.D., as an activator of genes in......about 170 pounds. "It's important to note that the ideal weight is not super-skinny," said Gustafson. "The average BMI for women who did not develop AD was 25, the border between healthy and overweight. A moderate, healthy weight seems to be best." The study is part of a larger population-based longitudina......ydrophobic nature of aerial structures could be an ideal property to prevent organisms from fouling in shipping. In our aim to find biological alternatives for antifouling compounds we are currently studying the antifouling properties of these highly surface active proteins," explains Dennis Claessen, of ...