Tag: "immunological" at biology news

JCI table of contents: 1 September, 2004

...proliferate in the lymph nodes, there was a strong immunological response that ultimately was followed by the devel...er interest, JAM-A/ mice also had showed a greater immunological reaction when their skin was exposed to an allergen as compared to wild-type mice. Further, wild-typ...

Fundamental change to Immunology 101

... — T cells are critically important for human immunological defenses against pathogens, yet little is known about their early development. T cells are made in the thymus, but ultimately come from hematopoietic stem cells in the bone marrow, from which all blood-cell types begin. A progenitor cell must leave t...

New glycan arrays discover autoimmunogenic activities of SARS-CoV: concern over monkey vaccine

...ole-viral SARS vaccine to human subjects since its immunological property remains largely uncharacterized. They sai... vaccinated subjects using glycan arrays and other immunological tools. Glycan arrays to exploring "sugar chain signatures" of infectious agents Wang and Lu empha...

K-State researcher working to improve alternatives to equine antibiotics

... peptides are produced by the body as an immediate immunological response to pathogens and generally target and kil...DNA sequences might be what stimulate an effective immunological response, Davis said. With hopes of helping to develop more powerful immune stimulants, Davis is exa...

Triple-vaccine strategy stimulates strong HIV-specific immune response in monkeys

...n chimpanzee adenovirus strains, which possess the immunological strengths of human adenoviruses without their drawbacks. Previously published proof-of-principle studies in mice showed that the new vectors were able to avoid the problem of pre-existing immunity. In the current study, the scientists created three v...

Lack of immune system protein prevents lupus-like condition in mice

...tists have used several animal models to study the immunological underpinnings of human lupus, a condition that afflicts approximately 1.5 million Americans with arthritis, prolonged fatigue, skin rashes, kidney damage, anemia and breathing pain. In one of these models, exposing mice to a hydrocarbon oil known as ...

JCI table of contents, 15 June 2004

...cal use. TITLE: A novel transgenic mouse model for immunological evaluation of carcinoembryonic antigen-based DNA minigene vaccines AUTHOR CONTACT: Ralph A. Reisfeld The Scripps Research Institute, La Jolla, California, USA. Phone: (858) 784-8110; Fax: (858) 784-2708; E-mail: reisfeld@scripps.edu View the PDF of...

Study helps explain island populations' susceptibility to exotic diseases

... of Upsalla, investigates the relationship between immunological investment (how developed is the body's immune system), native parasite abundance, and island size. The findings were published online June 8 in the Proceedings of the Royal Society of London. The paper helps scientists understand how island populati...

Strengthening independent junior research groups in collaborative research centres

...on" will primarily focus on the examination of the immunological role of dendritic cells, which are strong stimulators of defensive immune reactions. Scientists at the University of Erlangen-Nrnberg are looking in particular at the implementation of the most recent findings in immunology on the therapy of phenomen...

Susceptibility of mice to mousepox offers promise of smallpox protection

...tunity to study the outcome of such a longstanding immunological arms race in a mouse model of, for example, influenza. Karupiah and colleagues continue to probe the mousepox-triggered immune response. They're investigating not only interferon response, but also the killer T cell and antibody responses....

Mouse study yields clue to why liver is less prone to rejection, say Pitt researchers

...ay help to explain why the liver enjoys privileged immunological status over other organs, making it the least vulnerable to rejection when transplanted. Playing a central role in this mechanism is the dendritic cell, known for its ability to identify and present antigens, or foreign substances, to other immune s...

Researchers find no link between alcohol consumption during pregnancy and asthma during childhood

...lausibility of the fetal effects of alcohol on the immunological components of asthma." Yuan and his colleagues gathered data on 10,440 single-born infants who were born at 36 weeks of gestation or later to mothers attending midwife centers between April 1984 and April 1987 in Denmark. Mothers completed a questio...

Longer-term, moderate exercise improves immune activity

...ns of The American Physiological Society. Baseline immunological and physiological functions as well as lipid profiles were obtained from 10 men and 12 women, ages 54 to 82 years (median age 63.5), all retired. They then were trained in simple, moderate intensity resistance exercises, involving tubing and exercise...

JCI table of contents, 2 April 2004

...al finding as it relates to this disease and other immunological disorders. TITLE: Remarkably similar antigen receptors among a subset of patients with chronic lymphocytic leukemia AUTHOR CONTACT: Nicholas Chiorazzi North Shore-LIJ Research Institute, Manhasset, New York, USA. Phone: 516-562-1085 Fax: 516-562-102...

JCI table of contents, 15 March 2004

...nce in this study also indicates, indirectly, that immunological response may indeed be harmful by providing increased numbers of target cells for infection. The work here presents the first set of data to differentiate between helpful and harmful effects of the immune response to HIV, and may therefore contribut...

The catch 22 of immune response to AIDs viral infection

...nce in this study also indicates, indirectly, that immunological response may indeed be harmful by providing increased numbers of target cells for infection. The work here presents the first set of data to differentiate between helpful and harmful effects of the immune response to HIV, and may therefore contribut...

JCI table of contents, March 1 2004

...hat distinguish them from other DCs, however their immunological functions have remained mostly unknown. In the March 1 issue of the Journal of Clinical Investigation, Robert Modlin and colleagues from the University of California, Los Angeles, demonstrate that LCs are able to present non-peptide antigens of Mycob...

New genomics tool boosts diabetes research

...iption factors, including cancer, hypertension and immunological and neurological disorders. Discovering how transcription factors regulate genes in various human organs should continue to provide clues to the causes of disease and offer new approaches for therapy."...

Lunch workshop at the American Association for the Advancement of Science (AAAS) Annual Meeting

...ate continues about whether NAbs are just innocent immunological bystanders or a natural defense mechanism that diminishes the efficacy of biologic therapies. Professionals need expert synthesis and consensus. This program will outline in workshop style how a consensus was developed by the CMSC, the leading pro...

Fat cells fight disease, Purdue University researchers find

...that we want plenty of adipocytes to meet whatever immunological and endocrinological needs they fulfill, but we don't want them to overaccumulate lipid." In the January issue of The American Journal of Physiology, Spurlock and Kolapo Ajuwon, both of the Department of Animal Sciences and the Comparative Medicine ...

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