Tag: "immunology" at biology news

Heart size and function uncoupled by researchers

...sef Penninger, professor of medical biophysics and immunology at the University of Toronto, and lead author of a paper in the Sept. 20 issue of Cell. "We knew that cardiovascular disease triggers increased heart size and eventually heart failure so we set out to figure out if PTEN also has a function in the hea...

Researchers engineer virus that blocks common genetic defect

...the study, assistant professor of microbiology and immunology and a member of the Gene Therapy Center, the antisense sequences were incorporated into a lentiviral vector. "Lentiviral vectors appear to be the most attractive vehicles to carry therapeutic genes into non-dividing target cells such as the hematopo...

Evidence suggests that standard smallpox vaccine offers long-term immunity

..., Kenan professor and chairman of microbiology and immunology in the School of Medicine, and postdoctoral researcher Dr. Lawal Garba said despite substantial interest today "in the durability of immune responses following smallpox vaccination," little direct or quantifiable evidence of such durability exists. ...

Cloning pigs and drug discovery among 'hot' topics

...Dr. Randall E. Morris, head of transplantation and immunology research at Novartis Pharmaceuticals, AG, on leave from Stanford University School of Medicine, where he is professor of cardiothoracic surgery. Newly discovered drugs, some which currently are in development, are likely to have a great impact on the...

New mouse model shows how news of pathogen reaches immune system

...ing extent by dendritic cells. The entire world of immunology has been T-cell-centric for 20 years, but it's bec...ne response." The studies are part of a new era in immunology research where scientists can see live elements of the immune system, Yewdell said....

Smoking pot alters more than mood human immune system affected, USF/UCLA study finds

... Klein, PhD, professor of medical microbiology and immunology at USF. "However, because of the complexity of the immune system, we can't say yet whether the effect we've observed in humans is good or bad." A study by USF and UCLA is the first to show that healthy humans who smoke marijuana appear to alter the ...

Researchers discover how herpes tricks the immune system

...W. Virgin, M.D., Ph.D., professor of pathology and immunology and of molecular microbiology. "By targeting this viral protein or by manipulating the complement system, perhaps someday we can develop better treatments for herpes virus infections." The complement system consists of about 20 different proteins tha...

Peptide suppresses multiple sclerosis-like disease

...d chair of molecular virology, immunology and medical genetics at The Ohio State University College of Medicine and Public Health. The study appears in the Aug. 15 issue of the Journal of Imm...

Mice provide insight into bone metabolism disorders

...k Ross, Ph.D., research professor of pathology and immunology at the School of Medicine. Ross led the study, which appears online in Nature Medicine on Aug. 5 and will be published in the September issue of the journal. The first authors were Sunao Takeshita, Ph.D., and Noriyuki Namba, Ph.D., both post-doctora...

Ulcer-causing bacteria use stomach inflammation to their advantage

...long, says Berg, who also is a member of the tumor immunology program at the Alvin J. Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine. "The ability of Helicobacter pylori to adjust its adherence properties to the level of inflammation it causes at the stomach surfac...

UMass researcher helping the EPA to determine health effects of spent rocket fuel

...e chemical. Scientists in disciplines ranging from immunology to genetics submitted their comments to the EPA in May; the agency is expected to publish a proposed safe level called a draft reference dose late this summer. Zoeller notes that the draft reference dose is an early step in a lengthy process to det...

Making the most of lymphopenia

...utility on the basis of its simplicity," says TSRI immunology Professor Argyrios N. Theofilopoulos, M.D., who led the study. Theofilopoulos's study, which is published in the latest issue of the Journal of Clinical Investigation, suggests that immunotherapy should be initiated immediately after chemotherapy or...

Gene linked to type 1 diabetes

...ams Professor of Medicine and adjunct professor of immunology at the University of Washington in Seattle. "The identification of this gene will help us figure out how a gene can fully control if the rat will get diabetes or not. We think this gene may also contribute to human type 1 diabetes." Lernmark is senio...

Fluid forces within the body help invasive bacteria

.... Harry L.T. Mobley, professor of microbiology and immunology at the University of Maryland School of Medicine. He is not an author of the paper. "This describes a protein that sticks to things. Usually, we think of a protein either sticking to something or not sticking to something. Here we see a protein bindi...

Examining the healing mystery of Aloe

...t treating wounds. Dr. Ian Tizard, a professor of immunology in the College of Veterinary Medicine, is studying a special polysaccharide, the substance that forms along cell walls of the Aloe vera, to see how it performs its healing tricks. The Aloe vera is native to North Africa but now can be found almost...

University of Toronto researchers get to the heart of heart failure

...Josef Penninger of U of T's medical biophysics and immunology departments and lead author of a study in the June 20 issue of Nature. He and colleague Dr. Peter Backx, a physiology and medicine professor at U of T's Heart & Stroke/Richard Lewar Centre, found that when both genes - angiotensin converting enzyme (...

Scientists discover protein identifies damage to DNA

...d Aziz Sancar, Kenan professor of microbiology and immunology and Kenan professor of biophysics and biochemistry, respectively. Ultraviolet radiation, pollution and chemotherapy cause mistakes in DNA that must be repaired before the cell divides and propagates the mutations as cancer or other problems, Sancar s...

As bodies age, disease-fighting cells lose punch

...s responsive to new challenges, said Cambier. Most immunology researchers have believed that elderly people are less capable of fighting infection because their failing T cells no longer effectively orchestrate the cellular immune response. Although T cells do appear to play a role, Cambier and his colleagues ...

Study finds acute measles supresses HIV replication

...nternational health and molecular microbiology and immunology at the Johns Hopkins Bloomberg School of Public Health. Measles is a very immunosuppressive virus. It results in many secondary infections and is a major cause of death among children. Our findings show that measles also triggers intense immune syste...

First discovery of an immune system counter attack in the virus wars

...s Lanier, PhD, UCSF professor of microbiology and immunology and senior author on the paper. When we first foun...Hill, PhD, professor of molecular microbiology and immunology at the Oregon Health Science University; Ann Campbell, PhD, professor of microbiology and molecular ...

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