Tag: "immunotherapy" at biology news

Other highlights in the September 1 JNCI

...herapy--it may be able to work in conjunction with immunotherapy agents, the authors write. Contact: University o...noma Patients Interferon alfa immunotherapy is used to treat patients with metastatic melanoma or renal cell carcinoma, but efforts to improve t...

Scientists build on case connecting inflammatory disease and depression

...ch on patients whose immune systems are boosted by immunotherapy challenge this view and suggest that depression ma...s pathogens and kill cancer cells. Unfortunately, immunotherapy also causes depression in 33 percent of patients, as reported by Dantzer in 2002. Symptoms of depres...

Chemoradioimmunotherapy for advanced breast cancer: hope for the future?

...apy', combined chemotherapy, radiation therapy and immunotherapy in one. The chemotherapy component consisted of vi... addition of high energy radioisotopes, whilst the immunotherapy aspect was achieved by attaching an antibody specific to HER-2 to those radioisotopes, as well as th...

JCI table of contents, 1 July 2004

...cing tumor size. These results present a potential immunotherapy strategy for cancer treatment with appropriately reactivated anti-tumorspecific T cell subsets that already exist in patients' own body. TITLE: Specifically activated memory T cell subsets from cancer patients recognize and reject xenotransplanted au...

Cancer patient, heal thyself

...ing tumor size. These results present a potential immunotherapy strategy for cancer treatment with appropriately reactivated anti-tumorspecific T cell subsets that already exist in patients' own body. ...

JCI table of contents, March 1 2004

...ver cancer vaccines, the clinical effectiveness of immunotherapy has been disappointing. It is believed that defective presentation of tumor antigens by dendritic cells (DCs) to T cells and the subsequent defective stimulation of the immune response, may be the cause. In the March 1 issue of the Journal of Clinica...

PNNL recognized for commercializing technologies

...ratory's Electrodynamic Ion Funnel, alpha particle immunotherapy for treating leukemia and solid-tumor metastases, ...al applications. Cancer Treatment Alpha particle immunotherapy is the first treatment that targets metastatic cancers. This groundbreaking technology makes it poss...

Experimental Biology 2004 - Translating the Genome

...isms of tumor rejection, genetics of autoimmunity, immunotherapy of cancer, how the immune system is regulated, vaccine development and optimization, and determinants of protective immunity in clinical infection. Special guest Dr. George H. Atkinson, Science and Technology Adviser to Secretary of State Colin Powel...

JCI table of contents, February 2, 2004

...nity epitopes proves successful in mice Antitumor immunotherapy is a challenging endeavor since most human tumoras...n efficiency of low-affinity epitopes in antitumor immunotherapy AUTHOR CONTACT: David-Alexandre Gross Institut Gustave Roussy, Cedex, France. Phone: 33-1-69-47-25-...

Scientists develop a novel strategy to help prevent transplant rejection

... to disease-causing antigens has the potential for immunotherapy by 'reverse' vaccination, where we down-regulate an unwanted response to an antigen rather than stimulate it. This represents a huge opportunity to benefit patients and build our company. We have been extremely pleased to be able to get strong financ...

JCI Table of Contents, 15 August 2003

...t animal strains to EAE induced by MOG. Therefore, immunotherapy aimed at inducing tolerance to MOG might be beneficial in the treatment of MS. TITLE: Myelin/oligodendrocyte glycoproteindeficient (MOG-deficient) mice reveal lack of immune tolerance to MOG in wild-type mice AUTHOR CONTACT: Danielle Pham-Dinh ISER...

New Zealand biotech: An emerging global presence

...Kernohan ). Specialist peptides provide passive immunotherapy against HIV Virionyx Corporation Ltd. has co...ase I clinical trials of PEHRG214 (HRG), a passive immunotherapy against HIV, which the company has developed. The Phase I study was conducted at Beth Israel Deacone...

Researchers discover possible diagnosis, treatment, vaccine for mad cow, prion diseases

...uticals have uncovered the basis for a diagnostic, immunotherapy and vaccine, providing a way to detect and treat the brain-wasting damage of infectious prions like those found in mad cow disease and its human version, Creutzfeldt-Jakob Disease. Dr. Neil Cashman, a principal investigator at U of T's Centre for Res...

JCI table of contents, May 15, 2003

...ress/17295.pdf Alternative strategy for tumor immunotherapy TITLE: Antigenic drift as a mechanism for tumor evasion of destruction by cytolytic T lymphocytes AUTHOR CONTACT: Yang Liu Ohio State University Medical Center, Columbus, Ohio, USA. Phone: 614-292-3054 Fax: 614-688-8152 E-mail: liu-3@medctr.osu.ed...

DNA-based vaccine triples survival for dogs with melanoma

...onal Review Board. We felt it was useful to see if immunotherapy might help these very sick dogs with advanced melanoma since the response rates for standard chemotherapy were extremely poor with no evidence of improved survival." Canine malignant melanoma (CMM) is the most common oral cancer in dogs and accounts ...

Antibody therapy can increase the effectiveness of cancer vaccine, early studys

...ck. "This study makes a strong case that combined immunotherapy consisting of a vaccine and antibodies can elicit a potent immune response to some types of tumors in patients," says the study's senior author, Glenn Dranoff, MD, of Dana-Farber. The technique was inspired by the laboratory work of study co-autho...

JCI table of contents, March 3, 2003

...ityinto the design of protective vaccines in tumor immunotherapy CONTACT: Salem Chouaib CJF 9411 INSERM Cytokines et Immunite Antilumorale INSITUT GUSTAVE ROUSSY 39, RUE DAMILLE DESMOULLNS Villejuif Cedex, 94805 FRANCE Phone 1: 33-1-4211-4547 Fax 1: 33-1-4211-5288 E-mail: chouaib@igr.fr View the PDF of this com...

Proposed treatment for diabetes could have devastating side effects

...86% of the diabetic mice they treated with peptide immunotherapy died as a result. In humans type 1 diabetes is a s... trigger the autoimmune response. The idea of this immunotherapy is to trick the body into tolerating the cells that it would otherwise attack by "training" the immu...

Targeted immunotherapy eradicates cancer in mice

...n February 10. It is the first time that adoptive immunotherapy with engineered human T cells has demonstrated in vivo efficacy in mice. "Our findings represent a step forward in the field of adoptive T cell therapy," said senior author Michel Sadelain, MD, PhD, Head of the Gene Transfer and Gene Expressio...

Presence of certain tumor markers for melanoma could signal best results for vaccine

...stigator. "It also indicates that active-specific immunotherapy such as vaccines against melanoma may be particula...stage melanoma patients, of which 30 then received immunotherapy with CANVAXIN, a cancer vaccine (CancerVax Corp., of Carlsbad, Calif.). The tumors subsequently w...

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