Tag: "immunotherapy" at biology news
Promising biomarker for melanoma is identified
... tumor will recur and if additional treatment with immunotherapy
is warranted after the cancer is removed. Patients with early stage melanoma, called stage I cancer, have the thinnest lesions and are therefore the least likely to have a recurrence of their original cancer. The prognosis usually worsens as th...
Making the most of lymphopenia
...e Journal of Clinical Investigation, suggests that immunotherapy
should be initiated immediately after chemotherapy...d his colleagues suggests the anti-tumor effect of immunotherapy
could be increased if it were coupled with an injection of fresh T cells after chemotherapy or irrad...
Study finds autoimmune link in juvenile Batten disease
...ted clinical trial by NINDS researchers found that immunotherapy
significantly decreased stiffness and spasms in pa...ed to the same type of autoimmune response as SPS, immunotherapy
may help to slow the progression of Batten disease, says Dr. Pearce. While the new findings are intr...
UPCI presents study on discovery of protein that suppresses dendritic cells
... molecular basis for specific approaches of active immunotherapy
in cancer patients, said Michael Shurin, M.D., Ph.D., associate professor of pathology at the University of Pittsburgh and associate director of clinical immunopathology. This new direction, which one could term therapeutic molecular immunopathology,...
Multimillion dollar immunology research directed at edible or nasally delivered vaccines
...iscover potential targets for intervention through immunotherapy
or chemotherapy. In addition, partnership with the biotechnology companies Crop Tech and TechLab will permit application of research findings to the treatment of human diseases. Virginia Tech is a recognized leader in plant and animal transgenics as...
Experimental Biology 2002, Translating the Genome
...ines, for example), immune defects in HIV disease, immunotherapy
of cancer, and immune tolerance (an important issue in organ transplantation, for example). The American Association of Anatomists offers topics including angiogenesis (the growth of blood vessels, and of interest in cancer as well as heart resea...
Experimental treatment for hayfever is safe, effective, and fast
...ohns Hopkins researchers show that an experimental immunotherapy
for severe ragweed allergy dramatically reduces al... with chronic, severe ragweed allergy. Current immunotherapy
for ragweed allergies typically requires a tedious six-month build-up phase of shots, with subsequen...
Protein mix-up tied to suppressed immune response early in HIV infection
...response is important, particularly when designing immunotherapy
for an individual," Frelinger said. "Our study has scientific value in terms of understanding HIV pathogenesis in that it provides an excellent explanation of how a positive immune response some people make is actively broadly immunosuppressive." "T...
Potential allergy vaccine boosts hope for sufferers
...s are the key to a potential vaccine, or effective immunotherapy
- the practice of giving allergic patients small, ...afer and more effective alternative to the current immunotherapy
used to treat grass pollen allergies," says Associate Professor Prem Bhalla, joint leader of the gro...
Introgens gene drug demonstrates tumor growth control
... form of surgery, chemotherapy, radiation therapy, immunotherapy
or combinations of these and other treatments. This multidisciplinary approach to treating cancer was pioneered at M. D. Anderson. Because they focus only on cancer, experts here are renowned for their ability to treat uncommon or rare cancers as wel...
Immune system helps prevent tumors after all
...t. This is very exciting because it indicates that immunotherapy
has a significant potential use even for the treatment of tumors that are altered by the immunoediting process."...
Dendreon identifies novel approach to improve immunization efficiency
...novel approach with important implications for the immunotherapy
of cancer." The methodology described in the report is applicable to the development of a variety of vaccines and highlights a method for generating a strong immune response with a small amount of antigen. Dendreons current vaccine products in develo...
MS clinical trials confirm approach, demonstrate need to carefully refine targeted peptide therapy
...3 other research centers tested a type of targeted immunotherapy
designed to alter immune reactions to a specific protein, thereby treating the disease without compromising other immune functions. In this case, the therapy was an altered version of one segment of a protein called myelin basic protein (MBP). Ther...
Rockefeller University researchers discover immune-cell mechanism that boosts therapeutic antibody potency
... future. "This should have a significant impact on immunotherapy
for cancer," says senior author Jeffrey V. Ravetch, M.D., Ph.D., Theresa and Eugene M. Lang Professor and head of the Leonard Wagner Laboratory of Molecular Genetics and Immunology at Rockefeller. "There are more than 20 other antibodies now being de...
Hopkins study shows new target for boosting the immune system to improve cancer
... Johns Hopkins and senior author. "Onereason that immunotherapy
of cancer frequently doesn't work is that it's veryhard to keep the immune system responsive to tumors as they grow," explainsLevitsky. Researchers suspect that APC cells capture immune-triggering proteinsfrom dying cells, including tumor...
Study Suggests Vaccine Increases Survival In Ovarian And Breast Cancer Patients Following High-Dose Chemotherapy And Autologous Stem Cell Transplant
...eatment for advanced stage IV disease. "The use of immunotherapy
is more likely to be successful when there issignificant reduction in tumor burden," added Dr. Sandmaier, "In advanceddisease states, more aggressive therapy combined with therapy to stimulate thepatient's own immune system may prove to be effective...
Fred Hutchinson Cancer Research Center And Targeted Genetics Announces Issuance Of Braod Patent Covering Antigen-Specific T Cell Expansion
...expand antigen-specific T cells for use inadoptive immunotherapy
techniques, which has the potential to treat disea...sed thistechnology to Targeted Genetics. "Adoptive immunotherapy
represents a potentially powerful tool in the treatmentof infectious disease and cancer," says Ridde...
Wistar Research Yields Information About Colorectal Cancer Cell Invasion
...al tissues. "It is ironic," says Dr. Herlyn, "that immunotherapy
works against an antigenthat controls metastases and kills tumor cells. Obviously, connecting thetherapy success with the function of the antigen is the difficult part." According to Dr. Herlyn, "the GA733 antigen is the glue that makes tumor cell...
Researchers From Rockefeller University Develop Novel Method To Fight Cancer
...vidual's immunesystem," says Albert. "We hope that immunotherapy
will be available for peoplewith immune systems that don't match common MHC types." On a historical note, the dendritic cell was discovered at Rockefeller in 1973by Henry G. Kunkel Professor Ralph M. Steinman, M.D., and the late Zanvil A.Cohn, M.D. ...