DFG presents the 2004 MAK and BAT value lists
...rosol that according to current knowledge does not impair the health of employees exposed during eight-hour working days over the long term. Furthermore, the working substances are classified according to their carcinogenic, germ cell mutagenic, reproduction-endangering, sensitising or skin-absorptive effec...Excess thyroid hormone harmful to fetus
...ns that T[hyroid] H[ormone] excess can, by itself, impair embryogenesis of growing fetuses through transplacental passage of maternal TH.... Given the established importance of providing TH replacement to even mildly hypothyroid pregnant women, it is important to recognize that over-replacement appears to ...Joslin Diabetes Center launches research section on developmental and stem cell biology
...stress. In addition, excess glucose metabolism may impair expression of many genes that contribute to the progression of diabetic complications in general, thus her research using the early embryo and embryonic stem cells may lead to new treatments for other complications of diabetes. An additional contribu...Marijuana ingredient inhibits VEGF pathway required for brain tumor blood vessels
...bout the specific mechanisms by which cannabinoids impair angiogenesis, or whether the chemical might do the same in human tumors. To answer the first part of the question, the scientists induced gliomas in mice, which were subsequently inoculated with cannabinoids. Using DNA array analysis, the team exami...Genetic clues found for common congenital brain disorder
... brain abnormalities that can reduce coordination, impair mental function and cause hydrocephalus. In the September, 2004, issue of Nature Genetics -- to be published online August 22 -- the researchers show that in humans, loss of one copy of each of two adjacent genes, known as ZIC1 and ZIC4, causes Dand...Mouse study shows NPAS3 and NPAS1 genes may be linked to psychosis
...tional Institute of Mental Health. The illness may impair a person's ability to manage emotions, interact with others and think clearly. Symptoms include hallucinations, delusions, disordered thinking and social withdrawal. Most schizophrenia patients suffer chronically or episodically throughout their live...Green tea research leads to gum and other products
...lls and prevent side effects from medications that impair salivary function and cause dry mouth." For instance, oral cancer treatment can severely damage the salivary gland. "When this happens, the patient can no longer effectively secrete saliva and has a chronically dry mouth," Dr. Hsu said. Dry mouth als...JCI table of contents: 1 September, 2004
...ts MMP-9expressing macrophages and angiogenesis to impair cervical carcinogenesis AUTHOR CONTACT: Douglas Hanahan University of California, San Francisco, 513 Parnassus Avenue San Francisco, CA 94143, USA Phone: 415-476-9209; Fax: 415-731-3612; E-mail: dh@biochem.ucsf.edu View the PDF of this ...Proteins show promise for mosquito control
.... Those pesticides, although highly effective, can impair other organisms in the environment. Que Lan, insect physiologist at the University of Wisconsin-Madison, and her colleagues in the entomology department are working on a new, more targeted approach to mosquito control: inhibiting their ability to m...A probable cause for high blood pressure identified - shows links with diabetes
...accumulation of this molecule in the pancreas will impair insulin release, thus it is possible that this molecule is the long searched for link between these two disorders." The researchers found that imidazole-4-acetic acid-ribotide binds to imidazol(in)e receptors which are widespread throughout the brain...