Researchers Identify A New Cellular Structure: The "Dumposome"
...me is the first cellular component biologists have implicated in DNA elimination. Scientists had expected thatthe process would involve genetic markers that identify the doomed DNA, molecular scissors to snip it out, and enzymesto degrade it (all of which Allis suspects work in tandem with dumposomes), but they...ORNL Finds Common Genetic Cause For Epilepsy, Migraine
... to how the mutation affects cells' function. "The implicated gene affects the movement of calcium into and out ofspecific brain cells," Stubbs said. "This calcium movement regulates therelease of neurotransmitters, which are critical elements in thecommunication network among nervous system cells. "Calcium flo...Laser Microscope At Cornell Images Serotonin In Live Cells
...ts role in a host of human disorders. It has been implicated in central nervous system disorders such as anxiety, depression, obsessive-compulsive disorder, schizophrenia, stroke, obesity, pain, hypertension, vascular disorders, migraine and even nausea. Serotonin is synthesized in brain neurons and is releas...Scientists Urge Further Study Of Alarming Coral Reef Decline
...ural and man-causedscenarios. Some scientists have implicated higher seawatertemperatures, presumably from global warming. Other scientistshave found evidence for just the opposite, cooler than normalseawater temperatures. Still other theories blame pollution, oilspills and sedimentation caused by construction ...NIH Team Discovers Endocrine Tumor Gene
...d cancers. There is, for example, an unknown gene implicated in some forms of breast cancer also located at 11q13, which NCI researchers plan to explore, according to Dr. Liotta. A tumor suppressor gene acts like a set of brakes on abnormal cell growth. When a mutation in the gene occurs, the brakes are...E. Coli Genome Reported: Milestone Of Modern Biology Emerges From Wisconsin Lab
...isease,but related strains are toxic and have been implicated in an increasing number of human food poisonings from products ranging from ground beef to unpasteurized apple juice to fecally contaminated lettuce. With the K-12 E. coli genome in hand, Blattner said it will soon be possible to make a gene by gene ...Basin Traps Air Pollution In Mexico City: International Study Has Implications For U.S. Cities
...ed earlier this year. Peroxyacetal nitrate alsois implicated in the production of ozone, another irritant that makes breathingdifficult. An international team of scientists conducted the study, which was partof the Department of Energy's Atmospheric Sciences in Complex Terrain program --a long-term eff...Report Notes Difficulties In Eliminating E. Coli O157:H7 From Food Supply
... coli O157:H7 outbreaksin the United States, other implicated foods include raw milk, apple cider,dry-cured salami, lettuce, produce from manure-fertilized gardens, potatoes,radish and alfalfa sprouts, yogurt, sandwiches, and water. For a copy of IFT's Scientific Status Summary, contact Angela Dansby at (312)78...Peutz-Jeghers Disease Gene Identified: Enzyme Loss Causes Polyps And Cancer
.... Kinases have highly diverse functions and are implicated in cell cycle regulation, growth control and signal transduction. The molecular mechanism by which STK11 controls cellular differentiation in the gastrointestinal tract and in other organs is currently unknown. The search for physiologica...Common Cold Caused By Multiple Viruses
...infection with the rhinovirus, the virus mostoften implicated in colds. These findings support the recommendations that antibiotics, which donot work on viral infections, not be used to treat cold symptoms. The study appears in the February1998 issue of the Journal of Clinical Microbiology. Researchers from the......Nedlands, suggest that theprotein also probably is implicated in a third type of iron transport, callednontransferrin-bound iron transport. This type of transport comes into play, she explained, when there isexcess iron in the body, a condition that, if prolonged, can lead to abnormaliron deposi...Study Finds Gene Is Associated With Higher Risk Of One Kind of Stroke Among African-Americans
..., Fla. -- The variant form of a gene that has been implicated inthe most common form of Alzheimer's disease also may predispose blacks tointracerebral hemorrhages (ICH), a severe form of stroke, researchers from DukeUniversity Medical Center reported Friday. The researchers also found that overall, the...Phase Out Planned For One Of Top Five U.S. Pesticides, Plant Doctors Respond
...ts (methyl iodide has some promiseand has not been implicated as an ozone depletor) Development of plant varieties resistant to diseases methylbromide prevented Changes of cultural practices that increase the organic matterlevel of soil Soil solarization (the thermal heating of moist soil by sunlight) Electrica...Hormone Control Of Rare Leukemia Sheds Light On Molecular Basis Of Cancer
...mia (APL), theysimultaneously elucidated a process implicated in many other cancers. APL is abone marrow cancer that strikes about 3,000 people in the United States everyyear. "This study gets at the exact biochemical and genetic cause of theuncontrolled cell growth in this leukemia," says Mitchell A. ...Vitamin D Deficiency Appears Common In Hospital Patients
...its known effects on bone metabolism, vitamin D is implicated ina variety of other important areas -- including muscle function, progression ofarthritis and aspects of the immune system," says Finkelstein. "Because vitaminD deficiency appears to be so common, more people probably should considertaking vitamin ...Three-Dimensional Structure Of Human Lung Tryptase Determined, An Enzyme Involved In Allergic Asthma
...itis, and multiple sclerosis. Tryptase has been implicated as a causal mediator of such disorders and its involvement in the pathogenesis of asthma has recently been supported by preliminary results of clinical trials with the first synthetic tryptase inhibitors. The team at the Max Planck ...New Test Opens Window On Corrosive Free-Radical Activity In Individuals
... healthy people from free-radical damage,a process implicated in heart disease, stroke, and cancer, as well as suchnormal aspects of aging as wrinkled skin? Can some diseases be slowed orreversed with antioxidant compounds? Perhaps surprisingly, researchers have yet to answer these seeminglystraightforw...Tiny Worm Reveals Workings Of Suspected Tumor Protein
...lls in perpetual division. Yet while p300 has been implicated in leukemia,gastric and colorectal tumors, much mo...00 also interacts with CREB, atranscription factor implicated in memory, and is working to knock out a relatedgene in mice. More work is needed to better...Possible Trigger For Heart Failure Identified In Lab Animal Studies
... Previous research on congestive heart failure has implicated TNF -- socalled because it sometimes is associated with weight loss and tissuedegradation in cancer patients. Bryant and her Dallas colleagues say their findings indicate that heartmuscle cells are "a primary source of TNF secretion" during ...High Blood Pressure Caused By Salt Retention May Be Related To Oncogenes Implicated In Cancer
...lated to some of the same oncogenes that have been implicated inthe unchecked cellular growth of cancer. Dougla..."It was a complete surprise to us that an oncogene implicated in cancerdevelopment would also be used to turn on and off the function of a sodiumtransport cell," ...