Molecular motor implicated in tissue remodeling
...t with a net unidirectional motion. One-way motion indicates that energy is being utilized, so the team looked for an energy source. While most molecules that act as motors are inside cells and get their energy from a ubiquitous high-energy molecule called ATP, the team found that MMP-1 gets its energy by brea...Award winning researchers reveal potential new role for Glivec
...patient's response to treatment where the analysis indicates that the pathway targeted by imatinib is activated." Said Professor Cvitkovic: "These results fit perfectly the FNAB objectives supporting research using tissue sample biopsy for molecular analysis to select more accurately patients who could benefit...New research shows plants can shuffle and paste gene pieces to generate genetic diversity
...very of thousands of Pack-MULEs in the rice genome indicates that this may be an important mechanism to create new genes and new functions in rice and in other plants where MULEs are known to flourish. Recent studies indicate that species evolve through the generation of new genes and/or gene variants that he...Researchers identify protein promoting vascular tumor growth
... essential role in supporting proliferation of HEs indicates that accessory cells, such as macrophages, play a significant role in facilitating the growth of these tumors," Gordillo said. "Antibody-based therapy that blocks MCP-1 may be effective in substantially limiting the incidence and quality of the malfo...Winning combination to build bone density in children
... building and retaining bone mass. Their evidence indicates that children should engage in 25 to 40 minutes of vigorous activity and intake at least 700-800 milligrams of dietary calcium per day. For this study, vigorous activity could include actions like running, playing tag, jumping rope, etc. "You don't ...16 APS exercise research highlights, from reduced flu mortality to proteomics & obesity
...D). Substantial improved rate of force development indicates that strength training with emphasis on maximal mobilization in the concentric part of a leg press device improves work economy in COPD patients. 23.5 Stan L. Lindstedt, et al. (Northern Arizona University, Flagstaff) Design of muscle for function...JCI table of contents September 15, 2004
...ll death. Taken together, the data from this study indicates that regardless of the underlying genetic defect, ...ionally coupled EGFP-positive myocytes. This study indicates that while most engrafted donor-derived myocytes remain functionally separate from host myocardium c...9/11 search-and-rescue dogs exhibit few effects from exposure to disaster sites
...entration and alkaline phosphatase activity, which indicates that their livers were actively filtering toxins from their bloodstream. The serum globulins were also higher in the first year in deployed dogs, suggesting activation of the immune system. As the study progressed, however, these numbers came down ...Maine-based biophysics institute gets funding for first US-based 4Pi nanoscale microscope
...membrane. For example, a recent discovery at MMCRI indicates that controlling the migration of fibroblast growth factor can prevent reocclusion of coronary arteries after angioplasty. We are confident that this fruitful collaboration with the physicists in the IMB will reveal many as yet unsuspected discoverie...Viral suspect for amphibian decline traced to human spread through bait
... populations in the western U.S. The genetic study indicates that the virus may have been transmitted to remote locations through the vector of live bait infected salamanders being distributed and introduced to uncontaminated environments by fishermen and interstate bait wholesalers. A research article by a t...Final Alert: 16th EORTC NCI AACR Symposium
...e test clears way to targeted treatment New study indicates arsenic could be suitable first-line treatment for a type of leukaemia Prize-winning study shows Glivec effective in yet another type of cancer A revolutionary approach to anti-angiogenesis researchers find way to exploit tumour blood vessels Ne...Genetic map of important tree genes outlined
...genetic research with trees, Strauss said. It also indicates that the large majority of transfers of genes between widely separated plant species via genetic engineering would not produce novel characteristics, but simply modify existing genetic characteristics, he said. Just as Arabidopsis is the most commo...Single isolated mouse skin cell can generate into variety of epidermal tissues
... Research at Rockefeller. "This is first work that indicates a single skin stem cell can generate both epidermis and hair, even after propagation in the lab," Fuchs says. "The potential of these stem cells is very exciting." And in the future, she says, it may be possible to test if human skin cells can also b...Pig-human transplantation not PERVerted
...ssion into human cells in other mouse studies, and indicates the importance of developing robust models that do not contain additional replication capable viruses. Given the absence of direct human cell transmission of PERV, these work supports the potential safety of using pigs as source animals for transpl...Purdue study finds antioxidant protects metal-eating plants
... tissues without any ill effect. Previous research indicates that hyperaccumulators store metals in a specialized cell compartment called the vacuole. Sequestered in the vacuole, nickel and other metals can't damage other parts of the cell. But nickel still must travel within the cell in order to enter the vac...JCI table of contents: 1 September, 2004
...ssion into human cells in other mouse studies, and indicates the importance of developing robust models that do not contain additional replication capable viruses. Given the absence of direct human cell transmission of PERV, these work supports the potential safety of using pigs as source animals for transpla...Probing the surface of white blood cells to enhance immune system medicine
...nding tissue is known as 'extravasation'. Research indicates that microvilli may play a key role in this proces...racterizing their length and density, the research indicates that microvilli are dynamic structures that rapidly alternate between states of assembly and disasse...Discovery of new shrimp species adds to unique family
...s recent description of Bermudacaris australiensis indicates that it is far more widespread than once thought. It had been believed that the genus was found only in Bermuda caves but now researchers believe it is ecologically quite diversified. The information collected from description can help biologists tr...Length of sex act in flies dictated by genetics
...utes, including the length of the sex act. It also indicates that genes which were thought to be dedicated clock components seem to have a wide range of other effects that may have nothing to do with cyclic patterns of day and night. "These genes probably have important regulatory functions in many other area......t diet," he said. "And that's important because it indicates that the presence of more mitochondria in the muscles of these animals probably results in more burning of fat and the release of some energy as heat." "This leads me to believe that long distance runners, for example, possess a level of protection ...