Northwestern Scientists Discover How Herpes Simplex Virus Infects Cells
...f these receptors is to receivesignals required to induce cells of the immune or other system toproliferate or to die. A report of the protein discovery appears in the Nov.1 issue of the Journal Cell. "Knowing how this virus penetrates lymphocytestakes researchers one step closer to understanding how recu...Purdue Study Aims To Boost MRI Capabilities
...y," Nyenhuis says. "But pulses or fluctuations can induce electric currents in the patient, called eddy currents, which then may stimulate nerves and muscles." Little human data are available on the stimulating effects of MRI gradient fields, Bourland says. "Our research is aimed at determining at what leve...Virus May Be Linked To Obesity -- Early Findings Hint At Relationship
...sbirds and is found only in his native India could induce obesity when itwas injected into chickens. Human adenoviruses form a large family of some 50 viruses.Transmitted through the air, they can cause upper respiratory infections,cold symptoms, gastrointestinal problems and eye inflammation in hu...Newly Identified Tomato Gene Appears Key To Fruit Softening
... was found only when ethylene --a hormone known to induce and coordinate fruit ripening -- was either presentin the plant or applied externally. The researchers also identified genes closely related to LeExp1 in ripeningmelons and strawberries, an indication that this gene may be common in fruitsthat softe...First Salmonella Vaccine For Poultry To Be On The Market Soon
...akens the bacteria, allowing it in vaccine form to induce an immune response in a chicken without making the bird sick. When given a dose of the vaccine, newborn chicks, breeders and laying hens develop a lifelong immunity to salmonella. The immunity is transferred to offspring and eggs that people consume...Progress In Prion Research: Three-Dimensional Structure Of Prion Protein Fully Uncovered
...tein. In their malformed variant, prions appear to induce human Creutzfeld-Jacobdisease, and BSE, "mad cow" disease. The research team is supported by the SwissNational Science Foundation. Their work attracted attention a year ago when theypublished a first part of the structure. The research results to be ...Synthetic Vitamin E And Natural Vitamin E Are Equally Powerful Antioxidents
...nimum dose of 400 IUs of vitamin E is necessary to induce the antioxidanteffect. "In heart patients taking a minimum daily dose of 400 IUs of vitamin E,it doesn't appear to matter if it's natural or synthetic," he said. None of the subjects reported adverse effects from supplementation withe...Green Tea Ingredient Can Kill Cancer Cells
...d cells from the body," said Mukhtar. Polyphenols induce the demise of cancer cells, but scientists do not yet know why this happens, said Mukhtar. "It is likely that this compound conveys a message to cancer cells through a highly ordered and well-regulated signal transduction pathway that says, 'You must...Fruit Flies May Shed Light On Cocaine Addiction
...for which increasingly larger dosesare required to induce the same effects. Dr. Hirsh and Ms. McClung are already beginning to examine the genetic basis ofcocaine sensitization in fruit flies. One method they are using is to selectfrom vast collections of mutant flies those that respond differently to co...Ant Pheromone May Aid Alzheimer's Patients
...ergistically, and that individual chemicals do not induce the same behavioralresponse. Describing a laboratory experiment with ants following a trail of thefour-part cocktail that diverged into four trails of individual components, thechemists reported in "Naturwissenschaften". "They searched around, but...Fauci: New Findings Help Explain "Rebound" Of HIV In Patients Who Discontinue Triple-Drug Therapy
...n of immune system cells by immunization, can also induce latently infected cells to actively pr...nfected, resting CD4+ T cells, they were unable to induce with cytokines the production of HIV from the cells of either group of patients. ...Johns Hopkins Scientists Designing Compounds To Fight Malaria
...etweenlife and death. That form of the disease can induce coma andfevers as high as 106 degrees Fahrenheit. "A person cannot survive more than a few hours having cerebralmalaria," Posner said. The next step will be to determine whether it is safe whenadministered in large doses. Preliminary safety results a......ar the blocked vessels, the scientists were ableto induce neoangiogenesis -- the process by which the body c...ccountof the use of recombinant protein therapy to induce angiogenesis in humanhearts. FGF-I was obtained from strains of Escherichia coli by gen...Heart and Soul: The Blood Vessels And Brain Use Common Guide
...inclinical trials on both fronts, one using FGF to induce blood vessel growtharound blockages, the other using it to promote nerve cell survival after astroke. Children's Hospital is an independent 300-bed specialty care hospital, aleader in the field of pediatric research and education, and the pri...RNA-Dendritic Cell Combo Shows Promise As A Universal Cancer Vaccine
...e many antigens specific to that patient, and will induce potentimmune responses that will eradicate the cancer. This vaccine, when tested inanimals and in laboratory studies in a test tube was effective, said centerresearcher David Boczkowski, a contributing author. This is the type of vaccinethat will be ...... demonstrated E1A's ability tosuppress metastases, induce apoptosis (programmed cell death) and reverse theoverexpression of HER-2/neu, a cancer-causing gene. In patients with cancer,overexpression of the HER-2/neu oncogene is correlated with poor prognoses,increased tumor formation and metastasis and resi...Researchers Discover Existing Drugs May Prevent Enlarged Hearts
...roving that activated calcineurin is sufficient to induce cardiachypertrophy. At the least sign of stress the mice died. The appearanceof their hearts mirrored those of humans?dilated ventricular chambersindicative of heart failure. To confirm that activated NFAT3 alone could signal thehypertrophic ...Florida Or Bust? Older Lab Rats Seek Heat To Fight Infection, UD Researchers Report
...as placing an older patient in a very warm room to induce fever," shesays. Heat-Seeking Rodents Laboratory...eports. How much heat is needed to help older rats induce fever? The UD researchers havebeen trying to pinpoint an optimal fever-producing temperature by plac......y to inhibit tumor growth and suppress metastases, induce apoptosis(programmed cell death) and reverse the overexpression of HER-2/neu, acancer-causing gene. In patients with cancer, overexpression of the HER-2/neuoncogene is correlated with poor prognoses, increased metastasis and resistanceto chemotherap...American Cancer Society Grant Extended For Wistar Study Of Molecular Changes Leading To Cancer
...-causing gene,called Myc, which has the ability to induce malignant cell growth. Six yearsago, it was discovered that, under certain conditions, Myc can also cause cellsuicide. "This dual function," explains Dr. Prendergast, "means Myc may be a potentialAchilles' heel in the tumor cell that harbors it. ...