Drinking during pregnancy has yet another consequence: premature delivery
... period" during pregnancy during which alcohol can induce preterm birth. Based on animal studies conducte...s well as increased levels of prostaglandins could induce preterm birth in animals. Researchers discovered that alcohol could decrease progesterone and incre...Smells may trigger alcohol craving, and relapse, among alcoholics
Environmental stimuli like smells may induce craving for alcohol. Alcohol craving may increase ...covered that "alcohol-related cues" like smell can induce a neurochemical response in the brain that may "reinstate alcohol-seeking behavior" after withdrawal...Zebrafish's powerful heart gene could lead to transplant therapy
...different regulators, scientists have been able to induce a subset ofmyocardial characteristics in various experimental models, but never thecomplete beating phenotype, so there is something special about gata5 that cantake a cell that's not supposed to become a heart cell to actually become one,"said Stain...Targeted Genetics presents advances in synthetic gene delivery technologies
...emonstrated E1A's ability to suppress metastases, induce apoptosis (programmed cell death) and reverse the over-expression of HER-2/neu, a cancer-causing gene. In patients with cancer, over-expression of the HER-2/neu oncogene is correlated with poor prognoses, increased tumor formation and metastasis an...Researchers find new mechanism for growing new blood vessels
...angiogenesis. Now, it appears macrophages can also induce angiogenesis through the HIF-1alpha mechanism by p...udy by Simons and his colleagues suggests a way to induce a robust angiogenesis by simultaneously activating multiple growth factor families and other angioge...Molecular repair of ruptured discs
...ke to try stromelysin, with the idea that it would induce the production of more chemoattractant for the macrophages. "Once we figure out what the chemoattractant is, it might be possible to inject very small amounts of that." The studies illustrate how a clinical observation can inform basic science rese...Researchers show that proteins can transmit heritable traits
...because by simple laboratory manipulation, you can induce a cell to flip from one phenotype to another." By contrast, she said, techniques of using DNA mutation to alter such phenotypes are highly specific to each protein and cannot be reversed. In the article published in the journal Molecular Cell , Li...Advance in asthma research announced
...cells. Once blocked, the ability of eosinophils to induce asthma and allergic symptoms is greatlyreduced. Craig A. Rosen, Ph.D., Executive Vice President, Research and Development, at Human Genome Sciences, Inc., said,"I believe that working with our colleagues in Scotland, we have made a significant advan...Gene therapy halts HIV replication in cells from infected patients
...d approach, use of the antitat gene is unlikely to induce unwanted host immune responses that might eliminate cells expressing a foreign protein. The Children's Hospital of Philadelphia, the nation's first children's hospital, is a leader in patient care, education and research. This 373-bed multispecialt......xample where it has been demonstrated that one can induce the birth of new neurons and that they actually contribute to a complex behavior," says Macklis, associate professor of neurology (neuroscience) at Harvard Medical School. "It is a step toward attempting the same in mammals," he adds. The study play......ments, the researchers showed that they could also induce anxiety in mice by feeding them a drug that selectively blocked the Crhr2 receptor. Further tests, in which the researchers used drugs to turn the Crhr1 receptor on or off, ruled out the Crhr1 receptor as a cause of anxiety-producing activity. And...Exisulind (Aptosyn™) and other SAANDs compounds halt prostate cancer cell growth by two mechanisms
..., CP248 and sulindac sulfide to inhibit growth and induce apoptosis in prostate cancer cell lines, irrespect...hibit cyclic GMP phosphodiesterase and selectively induce apoptosis (programmed cell death) in abnormally growing precancerous and cancerous cells. Because SA...Targeted Genetics presents advances in systemic gene delivery technology
...demonstrated E1A's ability to suppress metastases, induce apoptosis (programmed cell death) and reverse the over-expression of HER-2/neu, a cancer-causing gene. In patients with cancer, over-expression of the HER-2/neu oncogene is correlated with poor prognoses, increased tumor formation and metastasis and ......es the ability of Aptosyn™ and other SAANDs to induce apoptosis through a novel mechanism of action," sa...ly demonstrated that Aptosyn™ and other SAANDs induce apoptosis in abnormally growing cells by a mechanism involving the inhibition of a novel expression ......hibit cyclic GMP phosphodiesterase and selectively induce apoptosis (programmed cell death) in abnormally gr...ncerous and cancerous cells. Because SAANDs do not induce apoptosis in normal cells, they do not produce the serious side effects normally associated with tra...UC Berkeley biologist disputes current dogma that genetic mutation is the cause of cancer
... polycyclic aromatic hydrocarbons all are known to induce cancer in humans, but none are mutagens. "The mutation hypothesis predicts that all carcinogens are mutagenic," he said. "Yet half of all carcinogens are not mutagenic, so how do they cause cancer?" Plus, Duesberg argues, if genetic mutations cause c...Nearly identical controls of immune genes in mice and humans hint at new asthma treatment
...says. Infections by hookworms and other parasites induce a potent response from cytokines Il-4 and IL-13, the researchers write. Hookworms are a major world parasite, infecting nearly a billion people. The half-inch worms commonly bore into the body through bare feet and make their way to the gut where the...Chemical discovered that causes plant tumors
...rst chemical of this type ever identified that can induce tumor formation in plants, they said. "This is an extremely active new class of chemicals that has a clear impact on plant growth regulation," said William Proebsting, a professor of horticulture at OSU. "We could observe its biological impact on th...Chemical from venom of Chilean tarantula could aid treatment of heart attack, other major diseases
...aminant in the final fraction, Suchyna was able to induce a strain of bacteria to express the pure peptide. The recombinant peptide blocked the channels as well as the peptide that came directly from the spider, their research showed. Sachs said this result opens the door to studies that require large am...Alcohol and thiamine deficiency together: a dangerous combination?
...thiamine," he explained, "you have the capacity to induce magnesium deficiencies, which have been linked to a number of alcohol's negative effects." He conjectured that thiamine-induced magnesium deficiency could be the root cause of a new sensitization to alcohol's effects. Another way of counteracting ...