Tag: "induces" at biology news

UCSF Researchers Pinpoint Molecule That Triggers Deadly Progress Of Pulmonary Fibrosis

...monary fibrosis inresponse to a drug that normally induces the condition. But there is more to the story. Th...with thecytoskeleton inside the cell. This in turn induces the integrin to change theshape of the molecule containing TGF Beta, allowing the TGF Beta to bind t...

Penn State Engineers Develop New Simulation For Ultrafine Particle Growth Process

... He and his group have shown that stirring induces aggregation oftitanium dioxide nanoparticles and affects their stability but has little effecton the rate of breakup. The presence of alcohols also promotes aggregation asdoes coating the nanoparticles with polymers. They have found breakup to beprom...

Brief Exposure To High Temperature Has Lasting Effect On Nervous System

... Ramirez. To test the idea that heat shock induces lasting modifications ofneuronal properties, Ramirez and Robertson exposed 50 locusts to 45 degreeCelsius temperatures (about 112 degrees Fahrenheit) for 3 hours, while controllocusts were kept at room temperature (about 70 degrees Fahrenheit) for th...

A Versatile Signal In Vertebrate Embryogenesis: Wnt-4 Regulates Kidney Development, Sex Organ Differentiation, Neuronal Survival And Axonal Guidance

...tion and recombination techniques. The uretericbud induces the mesenchyme to condense and to form tubules - precursors tonephrons. The mesenchyme in turn promotes ureteric bud proliferation andbranching. The ureteric signal can be mimicked by other tissues, in particularthe spinal cord. Andreas Kispert, whe...

Study Indicates Adolescent Smokers Are More Susceptible To Long-Term DNA Damage From Smoking Than Adults Smokers

...yage, a time of rapid lung growth and development, induces long-lastingphysiologic changes that impair the removal of damaged units in the DNA. Another possibility is that very young smokers accumulate more damaged DNA, andthat, even with repair, the damage remains many years after smoking cessation,in cont...

Invading Pests Harm People, Plants And Animals

...y tospread the bacterium Xylella fastidiosa, which induces Pierce's disease ingrapevines, almond leaf scorch disease, and a new disease known as oleander leafscorch. If oleander leaf scorch were to kill all the oleanders along the state'sfreeways, Caltrans would suffer a $52 million setback. Becaus...

Researchers Discover How The Immune System Shuts Down Faulty T Cells

...ass 1 proteins from the CD 8 cells, the tumor cell induces thedeath of the very cells that are supposed to destroy them. Indeed, when theresearchers allowed CD 8 cells to interact with tumor cells that had cast offsome class 1 proteins, the level of cell death among the CD 8 cells doubledwhereas the tumor ce...

Study Suggests Vaccine Increases Survival In Ovarian And Breast Cancer Patients Following High-Dose Chemotherapy And Autologous Stem Cell Transplant

...Alberta, Canada (NASDAQ: BIOM) (TSE, ME: BRA) that induces the body'simmune system to mount a response against cancerous cells. All patients were treated between Sept. 1, 1995 and Nov. 18, 1997. To gainpreliminary evidence of the potential efficacy of the THERATOPE vaccine, theoutcome of vaccinated patien...

Children are at greatest risk of eye damage during the eclipse

...ausing a rise in retinal temperature of 4 C, which induces photochemical injury to the retinal receptor cells. The condition may occur rapidly, without pain and without being immediately apparent and no treatment has been shown to be effective for the condition, says the author. Furthermore, photochemical ...

Immune molecule found to kill indirectly by closing receptor to live-saving help

...neurons cultured fromnormal mice. In mammals, IGF induces muscle protein synthesis, enhancing growthand weight gain, except in the presence of TNF, which is produced by immunecells in both the immune system and the brain. In neurons, the activity issimilar; IGF works to save damaged cells, but its ability ...

Learning how organs tell left from right

...s on other genes. Once the Nodalsignal arrives, it induces Pitx2 to help implement its directives. One testableissue in the current study, says Rosenfeld, "was to determine whether Pitx2implements the entire Nodal program or whether Nodal acts via additionaltargets." The results of earlier experiments that ...

Jefferson scientists propose mechanism to control the body's red blood cell and platelet production

...t "mild stimulation of deathreceptors and caspases induces a reversible inhibition of red cell developmentrather than apoptosis." This provides a key mechanism in fine tuning cell growthand differentiation. Such a novel mechanism may be of general significance, he says, andapply to diverse cell t...

Brain releases marijuana-like substance in response to pain, study finds

...njectionsof formalin, a chemical irritant that induces prolonged pain, profoundly elevated the anandamide levels inthe same location of the PAG in anesthetized rats. Although animals did not feel the pain, researchers wereable to observe pain modulation because the brain responds in the same way....

University of Pittsburgh-led team finds biological reason for women's increased risk of smoking-related lung cancer

... also discovered that nicotine found in cigarettes induces gene activity. Their report, published in the Jan. 5 issue of the Journal of the National Cancer Institute, offers the first biological explanation for the greatly increased risk women face versus men in developing lung cancer. If substantiated in ...

Molecular repair of ruptured discs

... growth factor called TNF-alpha. This factor then induces the disc cells to make the MMP stromelysin, which in turn results in the production of a chemoattractant molecule that pulls macrophages into the disc. The new influx of macrophages dumps out other enzymes that degrade the disc. While both Spengler ...

How a hormonal henchman triggers death

...ours to live. "We do know that the ecdysone pulse induces many genes in the gland, and it's possible that the burst of diap2 activity right before its death preserves an important final function it's trying to hold onto." One pleasant surprise, said Thummel, was that the pathways seemed relatively simpl...

AVAX Technologies' M-Vax™ cancer vaccine induces T cell mediated immune reactions in patients with metastatic melanoma

...r vaccine made from the patient's own tumor cells, induces T cell infiltration of metastatic sites. T cells ...ost importantly, the data suggest that the vaccine induces the expansion of novel T cell clones, targeted against the tumor. These T cells are involved in con...

Bone produced from skin and gum tissue

...e then engineered to secrete BMP-7, a protein that induces bone formation. The engineered cells are seeded onto collagen sponges, which are placed in the area where bone repair is needed. The research team---which included Bruce Rutherford, professor; Paul Krebsbach, assistant professor; Keni Gu, research i...

AVAX Technologies' O-Vax™ cancer vaccine induces positive immunological and clinical outcomes in patients with advanced ovarian cancer

...ncer extend earlier findings indicating that O-Vax induces a positive immunological and clinical response in ovarian cancer patients who are refractory to conventional chemotherapy. The presentation, entitled "Immunological and clinical effects of autologous, hapten-modified vaccine in patients with advance...

Virus linked to Kaposi's sarcoma sabotages immune system with a new and unusual strategy

...ignaling pathway from their internal location that induces the cell's surface proteins to carry out the sequestering of MHC-1. Ganem's lab has studied KSHV since its discovery seven years ago, and was the first to successfully grow the virus in culture. In the current research, the UCSF scientists systemat...

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