Emory researchers develop model to track the evolution of emerging infectious diseases
...verage number of secondary infections from persons infected with a disease stays below one. While the disease may still spread to other individuals, the pathogen lines of infection eventually become extinct, preventing the disease from epidemically spreading across the population. In their Nature paper, the...History of frog deformities suggests emerging disease
...rchers also found that the parasitic flatworms had infected specimens from six of the historical sites, suggesting that amphibian malformations caused by trematodes have occurred since the 1940s. When Johnson and his collaborators revisited these historic sites, they found that three wetlands continued to s...Gene mutation leads to super-virulent strain of TB
...ignificantly more bacteria from the organs of mice infected with the mutated tuberculosis (TB) bacteria than for mice infected with the unmodified, or "wild-type," strain. By 27 weeks, the mutant-infected mice started to die, w...Breakthroughs lead to better understanding in prevention of transfusion-transmitted infection
... screening, we've identified a large number of WNV infected units and seen a major improvement in the overall ...eactive; 212 of these donors were confirmed as WNV infected (0.031%, 1:3,215) based on detection of WNV RNA by PCR (polymerase chain reaction, an alternative NA...Budding viral hijackers may co-opt cell machinery for the getaway
... inside viral particles that had budded from cells infected with Moloney-murine leukaemia virus. On further examination, they also found two other proteins involved in endocytosis, a-adaptin and clathrin, inside the virions. However, Dynamin-2, a protein that binds to endophilin-2, was not there. This suggest...Communication is key to successful U.S. SARS quarantine
...apore, Taiwan and Vietnam. About 8,000 people were infected with SARS, with 780 fatalities in more than 25 countries. "It could have been worse without aggressive public health measures." SARS was a new virus that struck unexpectedly and the countries affected had little time to plan a response, Rothstein sai...Smallpox in Europe selected for genetic mutation that confers resistance to HIV infection
... direct person-to-person contact. Most people were infected before the age of 10, with the disease's 30 percent mortality rate killing off a large part of the population before reproductive age. "When you remove children from a population, you remove more of the reproductive potential for the species, compare...With flu season coming, don't forgetexercise?
...eritoneal macrophages were collected, prepared and infected with HSV-1. The virus was allowed to absorb for 90 minutes and, 72 hours after infection, anti-viral resistance was quantified. NK Flow Cytometric Assay : On the day of experiment, mice (n=12 per group) were either exposed to control or exercise tr...Enzyme revealed that is key to fungus's ability to breach immune system
..., whereas ordinary fungus survived normally. Mice infected with the flavohemoglobin-deficient C. neoformans survived for five days longer than those infected with the normally virulent strain. In contrast, the normal and mutant fungal strains were equally vi...Children with HIV more likely to utilize health services than infected adults
Although more American adults than children are infected with the HIV virus, children with the disease use ... approximately 4,000 children in the United States infected with the HIV virus (these statistics may not include data from all 50 states). "An understanding of...Scientists unraveling lice genome to halt blood-sucking pest
...d bumps on the skin. Scratching the rash can cause infected sores. In certain areas of the world, body lice may transmit fatal diseases such as louse-borne typhus. Pittendrigh and the lead researcher on the project, Joao Pedra, said understanding lice at the genetic level is critical to developing new methods...Catching evolution's henchmen in the act
...search allowed us to tell which invertebrates were infected and to identify strains based on one or two genes"...ith one another. Werrens group found that insects infected by Wolbachia cant produce offspring when they mate with closely related species infected with differ...Zadaxin in triple therapy shows 61% response for hepatitis C non-responders
... by PCR test (Roche Amplicor). Of the 20 patients infected with the difficult to treat HCV genotype 1, 60% (12/20) reported an EVR and 50% (10/20) tested negative for HCV RNA. As in all previous ZADAXIN studies, the safety profile was excellent without significant drug related side effects or toxicities. Du...University of Pittsburgh scientist honored for major accomplishment in cancer research
...erstanding of the most common malignancy in people infected with HIV." Dr. Chang, 43, co-discovered KSHV, also known as human herpesvirus 8, along with her husband, Patrick Moore, M.D., M.P.H., professor of molecular genetics and biochemistry at the University of Pittsburgh and director of the molecular biolo...Young cancer researchers honored
...mmon cancer in the population. Individuals who are infected with KSHV and whose immune systems are suppressed,...erstanding of the most common malignancy in people infected with HIV." Since discovering KSHV, Dr. Chang has continued to study the biology of the virus. In 199...Newly identified gene may halt fuzzy, moldy fruit
...etable drawer. Because spores spread Botrytis, one infected piece of fruit or plant will infect nearby plants. The fungus can start in healthy plant tissue but most often begins in dead leaves or petals that have fallen to the ground. Botrytis can live through the winter in a dormant state and then attack new...Improving the body's 'homeland security' against TB
... the bug moves out of its latent stage, the person infected is not only at a high mortality risk, but can infect others with TB. An estimated 10 to 15 million people in the U.S. have latent TB. Treatment for latent infections includes at least three potent antibiotics, but they must be taken alone or in combi...Experimental hantavirus vaccine elicits strong antibody response in primates
...e all but one of the post-challenge survivors were infected with Andes virus, no deaths were observed. "Aside from the immunogenicity of the vaccine in nonhuman primates, the most exciting thing about this was the indication that post-exposure prophylaxis might work--even five days out from exposure," Hooper ...Retroviral protein triggers proliferation of immune cells
... new study, however, shows that the protein forces infected cells to produce interleukin 2 (IL-2), a substance... view that this virus replicates mainly by causing infected cells to divide and proliferate rather than by generating more virus particles." The study provides ...Imperial researchers show novel flu treatment eliminates symptoms in mice
...ndistinguishable from uninfected control mice. But infected mice that had not been treated lost 25 per cent of their body weight, appeared hunched, withdrawn and lost their appetite - all characteristic symptoms of flu. When treatment with OX40:Ig was delayed for several days after infection, until the mice h...