Duke Scientists Engineer 'Stealth Virus' To Deliver Genes
...transgene unnoticed," Amalfitano said.To track the infective ability of their altered adenovirus, they inserted intoit a gene that turns blue any cell it infects. After the researchers injected this engineered adenovirus into mice withintact immune systems, "within three days, the modified virus had in...Wistar scientists find striking similarities between bacterial virus and human adenovirus
...ly to open up when suchparallels between different infective organisms are found." According to Wistar graduate student, Stacy D. Benson, "this finding reinforcesthe similarities between different biological systems. In fact, we suspect thatthis same architecture will also be found in viruses that infect pl......occal disease" actually encompasses five different infective diseases caused by Neisseria meningitidis (A, B, C, Y, and W135). Chiron currently has a conjugate vaccine against meningococcal C disease approved in the United Kingdom. However, there is no approved vaccine against meningococcal B disease, the mo...Common household items could be sources of infections
...upled with the published information regarding the infective dose (number of microbes required to cause an infection) and levels of disease-causing microbes called pathogens found in human fluids such as stool and nasal secretions (snot). The research was performed by Dr. Patricia Rusin, Dr. Charles Gerba an...Important pathogens and cures belong to little-known group of fungi
...d are pathogens of citrus fruits. Still others are infective agents of animal and human diseases, such as aspergilloses caused by the secondarily derived Aspergillus. The Herpotrichiellaceae (Chaetothyriales) is another example of a major fungal lineage derived from a lichenized ancestor that gave rise to op...New finding may identify unknown agents of mad-cow disease
... where it seeds the process again. Prions are thus infective and heritable without containing DNA or RNA as viruses do. According to Liebman, the finding that one prion can help start the chain reaction in another, totally different protein is important, because much more is known about how prions propagate th...Viruses help strep bacteria turn deadly
...xins and enzymes that may contribute to the highly infective nature of M3 GAS bacteria. Amazingly, one of the toxins resembles an enzyme found in potent snake venoms. Those molecules may prove to be useful targets for new drugs, diagnostics or vaccines. The research also opens the door to what Dr. Musser be...Researchers reach milestone in fight against lymphatic filariasis
...ansmitted to humans by mosquitoes containing these infective parasites. The juvenile parasites migrate from the site of the mosquito bite and ultimately develop into adult worms in the lymphatic system of the human host, where they cause the hallmark inflammation of filariasis. In many rural areas of Papua Ne...Genome analysis sheds light on drug-resistant pathogen
...e exposed to the bacterium. Those maladies include infective endocarditis, bacteremia, and urinary tract infections. Physicians often use vancomycin to treat opportunistic E. faecalis infections if other drugs fail to slow their progress. But the growing number of bacterial strains that are resistant to such a...Researchers learning how food-borne bacteria make you sick
...rapidly to the brain," Bhunia said. Only extremely infective bacteria can invade the brain because most pathogens cannot get through the brain's protective layer, called the "blood brain barrier." Bhunia said these Listeria strains can enter the brain within 72 hours of when tainted food is eaten. "This study ...Discovery may help in war against fire ants
...y entering a host. She found that the first-instar infective larva of the Strepsiptera jabs itself between the ...ated with the parasite, and released, or the first infective stage if it is the right sex could be sprinkled on mounds, he said....Tipping the balance of prion infectivity
...hat even changes in temperature could affect which infective form their chimeric prion assumed. Thus, they theorized, subtle mutations could cause species specificity by favoring one folded form over another. "We hypothesized that if something as minor as a slight temperature change could affect which misfold...UT Southwestern researchers receive $15.1 million in federal grants to study biothreats
... contaminated food, water, or soil; or by inhaling infective aerosols. It is one of the most infectious of the known pathogenic bacteria; examining an open culture plate can cause exposure. "It's a very dangerous organism to work with, and that's why so little is known about it," Dr. Norgard said. Tularemia is...Experiments establish 'protein-only' nature of prion infections
...hich the newly produced proteins folded into their infective shapes. "The use of temperature to influence folding was an elegant approach, because once you've changed the temperature, it leaves no trace in the solution," said Weissman. "There are no other molecules that it might be argued are contributing to t...Melvin Weinstein wins 2004 BD Award for Research in Clinical Microbiology
...cidal activity and therapeutic success in treating infective endocarditis and osteomyelitis, and in research on the clinical benefits of testing for Clostridium difficile toxin in hospitalized patients with diarrhea. He is known nationally for his expertise, as well, through committee service and advisory...Researchers in UGA Vet School discover a mechanism that blocks replication of a retrovirus
...ally harmless and cannot orchestrate production of infective virus particles. "Every sheep on the planet has e...ported endogenous retroviruses that interfere with infective retrovirus replication at different points in early states of the cycle specifically by blocking en......e human clot-forming system for the bacteria's own infective ends. "The theory is that the bacteria cause a local infection and begin to grow. Many of the bacterial products, as well as our immune cells, trigger the human clotting system, which evolved in part as a defense against such infection," said Ginsbur...