Curcumin may be an inexpensive, well-tolerated, and effective therapy for inflammatory bowel disease
...llation. Several parameters were determined in the inflamed mucosa. These comprised evaluation of macroscopic damage scores, histological evaluation of inflammation by hematoxylin and eosin staining, processing of tissue for Western analysis, and extraction of RNA for RT-PCR analysis. ResultsThis animal stud...JCI Table of Contents, September 15, 2003
..., which are protective in CIA, were reduced in the inflamed joints of CD69/ mice, correlating with the increase in other proinflammatory cytokines. Local injection of blocking antiTGF-beta antibodies increased CIA severity and proinflammatory cytokines in control but not CD69/ mice. These results show that CD...JCI Table of Contents, 1 October, 2003
... are mediated by effector T cells migrating to the inflamed and injured area. Inhibition of this migration has...tions. TITLE: Prevention of leukocyte migration to inflamed skin with a novel fluorosugar modifier of cutaneous lymphocyte-associated antigen AUTHOR CONTACT: Ch...UT Southwestern researchers receive $15.1 million in federal grants to study biothreats
...drenching sweats follow. Within 24 to 48 hours, an inflamed blister appears at the infection site and rapidly forms into an ulcer. Without antibiotic treatment, the infection can lead to respiratory failure, shock and death. Dr. Ellen Vitetta, director of UT Southwestern's Cancer Immunobiology Center, receive...FDA approves Raptiva (efalizumab) for chronic moderate-to-severe plaque psoriasis
...pidly accelerates, resulting in thick, red, scaly, inflamed patches on the skin surface. Psoriasis affects app...st common form of the disease, is characterized by inflamed patches of skin ("lesions") topped with silvery white scales. Psoriasis can be limited to a few spo...Biodegradable particles mimic white blood cells, target inflamed tissue, new study finds
...n mimic the ability of white blood cells to target inflamed blood vessel walls, according to a new study led by Ohio University researchers. The finding could be the first step in developing drugs that suppress specific sites of inflammation in medical conditions such as arthritis, heart disease and inflammat...The skinny on diagnosing skin disease
...people. The disease, which presents with hardened inflamed bumps or patches of skin, most commonly in the genital area, can result in severe scarring, resulting in impaired sexual activity, and can also be complicated by malignancy, most commonly squamous cell carcinomas. There are no biological markers or d...JCI table of contents, 1 June 2004
...people. The disease, which presents with hardened inflamed bumps or patches of skin, most commonly in the genital area, can result in severe scarring, resulting in impaired sexual activity, and can also be complicated by malignancy, most commonly squamous cell carcinomas. There are no biological markers or d...New discovery may help transplants survive
...atic vessels were present in the corneas that were inflamed (or under immune attack.) In the August Nature Medicine study, Dana and his colleagues hypothesized that when a cornea becomes inflamed, VEGFR-3 becomes activated on the antigen-presenting cells. They also believed that VEGFR-3 then triggered the AP...When is a mouse like a test tube?
...ugars Bertozzi targeted are produced abundantly by inflamed cells and by cancer cells, which means her techniq... metabolism, such as happens with cancer cells and inflamed cells that over-produce sialic acid. The technique opens the door to non-invasive imaging of sugars ...Columbia research to examine gene influence on severity of peridontal disease, therapy response
...itis can be classified based on gene expression in inflamed gums. Periodontitis occurs when infection of the g... and 60 with aggressive periodontitis. Samples of inflamed gingival tissue from the patients will be analyzed to identify local patterns of gene expression in ...IBD (Crohn's, Colitis) 'joins' cancer, inflammatory diseases in associated blood vessel growth
...creased vascularization is present in IBD, and the inflamed mucosal microenvironment actively promotes angiogenesis." Furthermore, he said that "the intestinal microvascularization of both CD and UC displays an activated profile as shown by the expression of angiogenic marker V3 integrin. "Targeting this inte...