Bacterial protein recycling factor possible key to new class of antibiotics
...ay argue that proposed antibiotics against RRF may influence mitochondrial protein synthesis," notes Kaji. Howe...o humans, showing little side effect despite their influence on mitochondrial protein synthesis. "With rational drug design it is even possible to design anti-RR...Innovative efforts target epigenetics, molecular imaging
...to figure out when and where epigenetic changes do influence health and disease." Among the first items on the researchers' to-do list is the development of technologies to speed identification of epigenetic marks and their locations across the entire human genome - to essentially create a map of the "epigenom...Hopkins to found first center for comprehensive study of epigenetics
...to figure out when and where epigenetic changes do influence health and disease." Feinberg, who pioneered the study of epigenetics in cancer, will lead the new Center for the Epigenetics of Common Human Disease at Johns Hopkins, which is funded by the National Human Genome Research Institute and the National I...Carnegie Mellon U. imaging study reveals sex-based differences that persist as mice enter adulthood
...cific brain structures change at puberty under the influence of sex hormones should help scientists understand ...al how structural sex-associated brain differences influence behavior and cognition." Ahrens and Kyoko Koshibu, a graduate student, captured images of intac...Yale researchers receive $4.5 million grant to study spinal cord repair
...ular and cellular technology to study factors that influence nerve signal conduction and to identify strategies that can protect, repair and support the injured nervous system. "SCI, MS and related disorders represent a major health challenge for our country," said Center Director Waxman, who is professor an...Genetic basis for individual variations in the response to stress
...thy subjects underwent genotyping to determine the influence of the T1521C single nucleotide polymorphism (SNP) in the GABAA6 receptor subunit gene (GABRA6) on the hormonal and autonomic responses to psychological stress induced by the Trier Social Stress Test (TSST). Adrenocorticotropin (ACTH), cortisol, dias...Scientist honored for studies of genetic influence on chemotherapy, tumor development
...ging our understanding of the genetic factors that influence the aging and death of cancer cells. The pro...n. "Dr. Lowe's finding that genetic mutations influence the selection of cancer cells for programmed cell death puts him at the threshold of significant adv...Melting ice cap gives urgency to new census of marine life project in Arctic Ocean
...Strait, and is sheltered from the North Atlantic's influence by the narrow Fram Strait and Lomonossov ridge, which juts up to within 1400 metres of the surface. Many species existing in the extreme frigid depths of the Canada Basin do not travel to shallower waters and are thought to have been there isolated...Study sheds new light on genetic risk for Parkinson's disease
...nson's disease," she said. These genotypes' influence on Parkinson's susceptibility is thought to be modest, as a number of factors may contribute. Thus, the number of subjects in an individual study may not have had enough statistical power to detect any links between gene type and Parkinson's, she add...NASA data shows hurricanes help plants bloom in 'ocean deserts'
... at the bottom of the food chain. The factors that influence their growth also directly affect the animals and organisms that feed on them. In addition, since climate-related phenomena like El Niño may change the frequency and intensity of hurricanes, storm-induced biological activity may have even greater con...Scientists learn how adjuvant makes vaccines effective
...Health Sciences Center. "We suspect that alum may influence the immune system in other ways as well. Our findings, however, have begun to unravel the mystery of adjuvants and will lead us in the future to better understand how they have helped prevent disease in millions of people. By understanding how they ...ESA and EADS-CASA sign contract to build instrument for the SMOS mission
...eatly improve our knowledge of the conditions that influence global ocean circulation and thus climate. Not onl...s advantage of the fact that moisture and salinity influence the emissivity of soil and seawater, respectively. From the information gathered, scientists will be...Ecology drives the worldwide distribution of human diseases
...e suggests that ecological and climatic conditions influence the emergence, spread, and recurrence of infectiou...ael Hochberg, and Jean-Francois Guegan address the influence of ecological factors on the biological diversity and distribution of parasitic and infectious disea...MIT technology jump-starts human embryonic stem cell work
...o do so is difficult. Several factors are known to influence their behavior. One of them is the material the cells grow upon outside the body, which is the focus of the current work. "Until now there has been no quick, easy way to assess how a given material will affect cell behavior," said Robert Langer, the ...Trapping carbon in soil key for protecting global food security, dealing with climate change
... world's degraded agricultural soils will directly influence global food security and climate change within our lifetime, said Rattan Lal, author of the article and director of the carbon management and sequestration center at Ohio State University. Scientists estimate that, since the mechanization of agricult...New research shows that the seasons may be involved in onset of menopause
...." "The seasonality we found seems to support the influence of environmental factors on female human reproductive functions even when they are declining. The pattern of the peaks following the equinoxes appears to be similar to the bimodal distribution of conceptions in Eastern Europe," he said. The questionn...Earstones tell fishes' tale of early life in the Colorado River estuary
...at the edge of the continents. Rivers have a large influence on coastal marine ecosystems. These economically important marine fish were affected when we turned off the water upstream."...First ever standards linking climate change, biodiversity and poverty seek global peer review
...el Corporation. "We hope that these standards will influence the array of policies that are emerging at the state, national and international level. Current policies to reduce global warming emissions do not do enough to encourage land use projects with biodiversity and social benefits," said Tia Nelson, Direc...Common worm provides insights into salmonella virulence
...should be able to figure out how virulence factors influence the innate immune response." Aballay said that the C elegans system could be an effective living model for testing or screening new compounds or drugs for treating Salmonella in humans. However, he added, much additional research in other living mode...From lung to gut the Wnt signaling pathway transforms cell fate
...gs of transgenic mice that had developed under the influence of artificially high levels of activity in the Wnt signaling pathway, caused by the presence of an activated b catenin gene. They found that although externally the lungs looked normal, the interior of the lungs had lost the normal branching tree-lik...