Noggin mutation causes rare congenital hearing loss
...ing sound vibrations from the outside world to the inner ear and brain. "About 1 percent of Americans have been diagnosed with otosclerosis, but it may affect up to 10 percent of the total population," says Marci Lesperance, M.D., an assistant professor of otolaryngology-head and neck surgery in the U-M...NIGMS energizes NMR research with world's biggest magnets
...copy to have faster, more accurate glimpses of the inner workings of molecules and to study ever-larger molecules, rolling back a major limitation of the technology. The National Institute of General Medical Sciences will support the construction of four new custom-built 900 MHz NMR magnets--the largest si...Decision making at the cellular level
...ge makes it through the outer cell membrane to the inner nucleus, the cell is busy activating a molecular switch to guide how the message will be delivered in the first place. "Our results add a layer of complexity to understanding how messages are communicated by cells," says Mark Donowitz, M.D., profess...Two new monkey species discovered
...kable for its dark orange sideburns, chest and the inner sides of its limbs, its reddish-brown back, and a ...with a black forehead and red sideburns, chest and inner sides of limbs. Since fishermen brought it to Van Roosmalen's Breeding Center for Endangered Wildlif...Genetic fingerprint of lung cancer predicts treatment outcome
...ll at once provides unprecedented insight into the inner workings of individual lung tumors. "The goal is to further refine the fingerprint and eventually produce a lung cancer-specific microarray for testing in clinical trials," said Dr. Frances Shepherd, the Head of the Lung Cancer site group at Universi...HHMI selects new clinical investigators
... biology that have revealed new concepts about the inner workings of the human cell, said Joseph L. Goldstein of the University of Texas Southwestern Medical Center at Dallas and chairman of HHMIs Medical Advisory Board. What are crucially needed are more patient-oriented researchers with the expertise to ...Researchers discover clues to whale evolution
...ege of Medicine (NEOUCOM), has discovered that the inner ear of whales evolved much more quickly than expec...e organ responsible for balance and located in the inner ear, was adapted to aquatic life approximately 45 million years ago. The discovery will be publishe...Hopkins scientists reveal how sound becomes electric
...ohns Hopkins have discovered how tiny cells in the inner ear change sound into an electrical signal the bra...at the Johns Hopkins School of Medicine. "When the inner ear detects this wave, a burst of chemicals is released and a nerve sends an electrical signal to th...Setting the stage for limb development
...he Dlx5/6 knockout mice displayed defects in bone, inner ear and craniofacial development. But most interestingly, the mice were also born with the claw-like limb deformities characteristic of SHFM. This work is the first demonstration that Dlx genes function in mammalian limb development, and it establis......O is produced by endothelial cells, which line the inner surface of all blood vessels. NO is a potent relaxing agent of arterial smooth muscle. It plays a major role in keeping the blood pressure of an individual from becoming dangerously high and in preventing blood vessels from spasming. In addition, NO ...New findings could lead to innovative treatment technologies for patients with sickle cell
...d P-selectin on the surface of the cells that form inner lining of the blood vessels. It is this P-selectin to which the sickle red cells stick to eventually cause a blockage to flow of blood. The results are recurrent pain and organ damage. The second finding from this research shows that that the adhes...Angioplasty beats clot-busting drugs for most heart attack patients
...inflated, compressing the plaque and enlarging the inner diameter of the blood vessel so blood can flow more easily. In the C-PORT study, 70 percent of the patients also received a stent a metallic device that looks somewhat like a spring in a ballpoint pen. For the study, the investigators created a fo...Study links gene to success of a treatment for high blood pressure
...sed in Seattle. Adducin is a protein linked to the inner surface of cell membranes, and one adducin genetic variant (Gly460Trp) is known to increase sodium retention by the kidney. High-salt diets, as well as sodium retention, are one cause of high blood pressure. (Table salt is sodium chloride.) Diure...Fisheries forecasting in the Niger inner delta
..., annual catches depend on river flood levels. The inner delta of the Niger, one of the most extensive floo...ful tool for improving fisheries management in the inner delta of the Niger which supplies a significant amount of protein for the people living in the regio...Lizards and salamanders may use lungs to hear, study says
... ears, both groups of animals have inner ears that can process sound. ... by air from the lungs to the animal's inner ear where it is processed as sound. The experiments make cl...Nabi experimental vaccine reduced Staph aureus bloodstream infections by nearly 60 percent
...(bacteremia), to the bones (osteomyelitis), or the inner lining of the heart and its valves (endocarditis), or cause abscesses in internal organs such as the lungs and kidneys. Most at risk for these infections are surgical patients, trauma or burn victims, newborns whose immune systems are not yet develo...A new route to branching morphogenesis
...d branching, and causes rounded clusters of murine inner medullary connecting duct epithelial cells to generate tubules in culture. Unlike HGF-stimulated morphogenesis, which is mediated by the Ras signaling pathway, these responses depend on activation of protein kinase C-a. Nickel et al. find that the tw...The body's production of melatonin may be the reason why the elderly can't get a good night's sleep
...But now, a new study asserts that it is the body's inner clock -- involved with the production of melatonin -- which may be the obstacle to a good nights sleep. This challenges the marketers notions that the problem is a deficiency of the hormone itself. Background One of the most prominent changes in slee......t of the first axis of an animal-which defines its inner and outer layers and is initiated by the entry of ...layers-such as its skin and nervous system-and its inner layers, such as its muscle, gut and reproductive organs. "What we discovered are some of essential ......oli cell. As the tail tube punctures the outer and inner membranes of the E. coli cell, the virus' DNA is injected through the tail tube into the host cell. The DNA then instructs the bacterium to produce new viruses. So many are produced, in fact, that the E. coli eventually bursts, setting masses of ...