ORNL researchers expect big things from nanostructures
...archers to attach DNA to the nanofibers. When they insert these nanofibers into cells, the DNA can be used to program the cell to produce new proteins, but it is not free to move around within the cell. As such, it has a less likely chance of inserting into the cells chromosomes or being segregated to daugh...Engineered proteins will lead to 'synthetic biology'
...ogy.'" Thus, the scientists showed that they could insert either the TNT-binding protein or the lactose-binding protein into E. coli bacteria in such a way as to activate a "reporter gene," which signaled that their molecule had become a functioning component of the bacterial genetic machinery. Such experim...Borrowing from Ebola virus could aid cystic fibrosis gene therapy
... is mutated. Thus, researchers aim to find ways to insert functional versions of the genes into the airway cells of people with the condition. In their investigation, the researchers attached the Ebola protein piece to a modified feline immunodeficiency virus, which causes leukemia in cats but no disease in......s used to deliver the gene in the French studymay insert it near Lmo2 about once per 100,000 insertions. Si...the risk." This includes modifying viruses so they insert genes only in specific sites in the genome, or adding self-destruct mechanisms so doctors could kill...Ann Arbor chemist wins national award for extracting sulfur from fuel
... engineer at the University of Michigan. The hairs insert so close to a surface that their molecules actually attract each other in a brief defiance of gravity. But why study adsorption as a separation technique? "Over 90 percent of separations in the industry are done by distillation," or selectively boili...First population study of GM mosquitoes highlights difficulties facing malaria control technique
...ed a stable and proven gene transfer technology to insert a green or red fluorescent marker into four different lines of the mosquito Anopheles stephensi, the major carrier of malaria in India. In control population studies containing GM mosquitoes only, the fluorescent marker was maintained intact and pas...Marine biologists probe 'black box' mysteries of the sea
...workers drill holes into the rocky shoreline, then insert a dynamometer into each hole. When a wave hits the plastic golf ball, it stretches the spring, giving researchers an accurate measurement of the amount of force that struck the shore. "The dynamometers see a lot of force, but it varies from place to ...Vaccine technique shows potential against common form of lung cancer
...ents tumor and using specially equipped viruses to insert a gene known as GM-CSF into the tumor cells. After being radiated and injected into the patient, the manipulated tumor cells began producing the granulocyte-macrophage colony-stimulating factor (GM-CSF) protein, which acted as a magnet for an immune ...ORNL, Georgia's Isotron develop promising new cancer treatment
...californium-252 source, which allows physicians to insert the radioisotope through a catheter directly to the tumor site. Martin and colleagues were able to reduce the diameter of the source by more than half from the previous standard of about 2.8 millimeters. This makes it possible to reach and treat tumo...Expanding the genetic code--TSRI scientists synthesize 21-amino-acid bacterium
...cid, then he would have a way to site-specifically insert the unusual amino acid into any protein he wanted.... system, a ribosome that was reading an mRNA would insert the unusual amino acid when it encountered UAG. Furthermore, any codon in an mRNA that is switched t...USC researchers use gene therapy to prompt mouse cells to produce human collagen
...nstitute for Genetic Medicine, has been working to insert that gene into cells that are missing it. They have been able to get the collagen gene into both fibroblasts (the cells that normally produce collagen and other fibrous tissues) and keratinocytes (the cells which normally differentiate to form the ou...UCLA/Caltech scientists develop new gene therapy approach
... tools, but scientists have been baffled at how to insert them into the immune system in stable form. You can't just sprinkle them on the cells," said Dr. Irvin S.Y. Chen, director of the UCLA AIDS Institute. "Our research is the first to create a delivery system using a vehicle derived from HIV itself," he...Biologists raising baby loggerhead turtles for conservation find disturbing gender trend
...genders. This involves a small incision to briefly insert a tiny scope and examine the babies' gonads. "These turtles have very small gonads at this age and are difficult to identify," said Wyneken, who performed the surgeries. "By relying on several different criteria we were able to get the information."F...Tailor-made sugar coated proteins manufactured in novel E. coli system
...o proteins. Colleagues in Zurich were then able to insert the C. jejuni glycosylation machinery into E coli and test whether it worked using mutational analysis. "We have only begun to scratch the surface in understanding important role sugars play in our body," said Professor Dell. "Many common diseases in...First potentially clinically useful independent marker for lung cancer identified
...ells divide: they remove the faulty bit of DNA and insert a corrected copy. This repair stops errors being transmitted through generations of daughter cells. Without the repair the daughter cells would gather further mistakes and the damage would multiply, resulting in a group of rogue cells the start of c...Stanford researchers develop gene therapy technique that sharply cuts risks
...ene therapy trials, while retaining the ability to insert therapeutic DNA into specific sites in the chromos...the study. The goal of gene therapy is to insert a healthy copy of a gene into a cell where it can take over for a faulty version. If the therapeutic...Researchers create new strategy for removing arsenic from soil
...imal health worldwide. The scientists were able to insert two genes from the common bacterium Escherichia coli that allow a member of the mustard family called Arabidopsis to tolerate arsenic, which is usually lethal to plants. Arabidopsis can then remove arsenic from the soil and transport it to the plant'...Gene therapy reverses muscular dystrophy in animal model
...n gene. In the past, researchers have been able to insert the gene into newborn mice via adenoviral vectors. But those vectors have many viral properties, and results have been limited because adult mice and mice that have begun to develop symptoms of the disease developed a sharp host immune response that ...Stanford researchers devise novel gene therapy technique
...lace. An ideal gene therapy for this disease would insert a copy of the gene into the skin cells where it co...version of that DNA sequence. When the researchers insert a copy of the therapeutic gene and a gene coding for integrase into a human cell, the integrase inse...Of mice and men: Deaf mouse leads scientists to new human hearing loss gene
...ild a virus-based "vector" that will allow them to insert a normal Tmie gene into mice that carry a mutated version of the gene, in an attempt to correct the problem. Kohrman's colleague Yehoash Raphael, Ph.D., M.Sc., who directs Kresge's Otopathology Laboratory, will continue to aid the reseach using an el...