HIV targets active genes in cells
...genetic disorders by using a mutated retrovirus to insert a new gene into a defective genome. Gene therapy could be made safer and more effective by knowing more about and taking advantage of a retrovirus's targeting specificity, he said. Retroviruses like HIV reproduce themselves by infecting a cell, makin......he most promising of three zona pellucida genes to insert into the myxoma virus. But this sterilised less than 25 per cent of rabbits. Now they have switched to the ZPC gene, with much better results. In two trials in May, New Scientist has learned, the latest transgenic myxoma virus sterilised 8 out of 11...Rutgers scientists create high-protein corn with Third World potential
...ally modified organism or GMO, in which scientists insert a gene that is not native to the plant. A patent is currently pending on the new corn. The first test application of the methionine-enhanced corn was in chicken feed. Formulation for chicken feed is very expensive, employing corn, soybean and synth...New amino acid discovered; Fundamental building block of life
... transfer-RNA (tRNA) needed to insert the new amino acid into protein, as well as another important enzyme essential to the process. These two discoveries, along with the detailed crystalline structure, convinced the teams that ...A possible new way to block HIV infection of healthy cells discovered
...s, are thought to act together to let HIV bond and insert its replicating machinery into cells. Only in rare cases and never involving membrane-class proteins have reverse-chirality peptides bound at identical receptors. We didnt have any expectation that our synthesized peptide would bind to the CXCR4 r...Freezing cancer cells makes them prime targets for anti-cancer drug, new study finds
...thor of the study. In the procedure, cryosurgeons insert a thin probe cooled with a cryogen - often argon gas or liquid nitrogen - into a tumor, turning the malignant mass into an ice ball. Doctors see precisely where they are operating in real time and can thus avoid freezing healthy tissue through the us...'Vigilant vector' could insert genes that sense, prevent heart attacks
...associated virus, a commonly used gene carrier, to insert the cardio-protective gene switch. The approach is a classic example of bionanotechnology, or manipulating basic elements of biology such as DNA and proteins for research and therapeutic purposes, Phillips said. UF researchers pioneered the use o...Scientists reveal secrets of infectious childhood heart disease
... from phages, viruses that can invade bacteria and insert large numbers of genes into the bacterium's own DNA. The presence of "swappable" toxin genes has important implications for understanding GAS outbreaks because it provides a mechanism for bacteria to exchange genes among themselves. To see if indi...Mating molds provide new insights into speciation and human reproduction
...o weeks for a genetic cross to mature, and you can insert or delete any gene you want." When it comes to sex, molds and humans share at least one fundamental principle: In both species, the parents must donate a copy of their DNA to the offspring in order to successfully reproduce. In most human cells, DNA ...Protein study suggests ways to help humans thwart viruses
...es that use a unique production method to copy and insert their genetic material into a host cell. Human cells also contain specialized receptors for retrovirus entry, Sanders says. "Such receptors are often very specific," he says. "We know, for example, that people who don't have the receptor for HIV are ...New book on warnings can help save lives
...e 1973. Topics include warnings on printed labels, insert sheets, product manuals, signs, and speech commands. Warnings effectiveness is assessed by speed, comprehension, memory, judgment, and behavioral compliance measures. Warning applications include labeling on or accompanying consumer products, signs i...A new model of cerebral cortex development
...loped a microsurgical technique that allows her to insert genes into the cortex of mice while they are still in utero, about halfway through gestation. The mice are born normally and can be analyzed at any age. Fibroblast Growth Factor 8 (FGF8), a member of a family of signaling proteins involved in forming......is study, Dr. Condic used a modified adenovirus to insert extra copies of a gene for one kind of integrin protein into sensory neurons taken from adult rats. A second group of neurons received extra copies of a different integrin gene. The additional genes produced levels of integrin in the adult neurons ...Study reveals molecular key to tumor suppressor activity
...o take tumor cells in which p53 is not working and insert functioning p53 into the nucleus and it will remain there." In addition to further understanding a cellular control mechanism of p53, Xiong's findings have other implications. "Protein transport is a major regulator of cellular function. This repre...Scientists find link between Indian caste rank and genetic similarity to Europeans
...ulations were mostly male, and that they tended to insert themselves into high ranking positions in the developing Hindu Indian caste system....Genetically modified earth plants will glow from Mars
...ence completed. To create the glow, the team will insert "reporter genes" into varieties of the plant, which will express themselves by emitting a green glow under adverse conditions on Mars. Each reporter gene will react to an environmental stressor such as drought, disease or temperature. Forexample, one...Scientists determine how chemistry keeps weird worms "out of hot water" at steaming deep-sea vents
...re slender attachment, the scientists were able to insert the device right into the Pompeii worms home. They found that the Pompeii worm resides in much hotter water than the tubeworm, with temperatures fluctuating from 40 90C (104 194F). According to Luther, this hot water causes an important chemical re...With an eye on safety, UF experts explore cellular mechanisms of gene therapy
...potential risk is that the DNA from the virus will insert into the DNA of the cell and in doing so change the characteristics of the cell from being a normal cell to a cancer cell. One way this might occur would be if the new DNA was able to effectively switch on a previously silent tumor-causing gene." In ...Plants as plants: gene could convert crops to plastics factories
...make those compounds and by using biotechnology to insert the genes into crop plants. Until now, however, the problem has been trying to get plants to make enough of these substances for the whole process to be economically viable, he says. Although crude oil supplies are finite, petroleum has been a much l......slated proteins." The repetitive elements seem to insert into non-coding regions of a gene and be incorporated into protein through alternative splicing. Because the elements contain splicing sites--places where the editing machinery of the cell cuts genes for translation into proteins--new proteins may be...