Tag: "insert" at biology news

Human genome bears a virus related to HIV-1

...ademy of Sciences. During infection, some viruses insert their DNA into the host's genome and direct the host's cellular machinery to make the proteins needed to assemble more viruses. If this gene insertion takes place in a cell that will become an egg or a sperm, the host's offspring will have a copy of ...

Mosquitoes have discriminating tastes, UF researchers find

...ll they find a site thatfeels or tastes good, then insert their stylet. The stylet moves through thetissue "like an oil-drilling rig" working around objects and turning at angles.When it detects the mother lode -- a capillary -- it taps right in. Butler says the study has far-reaching implications for backy...

Social behavior transformed with one new gene

...his same region, thereceptor gene was missing this insert in montane and meadow voles, which arepromiscuous and frequently live in isolation. To determine if this sequence difference was important for thedistribution of vasopressin receptors in the brain, the Emory team incorporatedthe prairie vole ...

U-M scientists identify genes that make blood "thicker" and more likely to clot as we get older

...ntists then used genetic engineering technology to insert these humanminigenes into fertilized mouse eggs to create transgenic mice that producedhuman Factor IX, in addition to the mouse version. After the mice were born,Kurachi and his colleagues selected three to six founder mice for each humanFactor IX m...

Gene therapy trial using cold virus to begin at UK

...y restoringnormal function of the gene. To insert the corrective gene into the nucleus, the corrective gene canbe encapsulated in liposomes, small balls made of molecules that resemble cellmembranes, or viruses. The adenovirus, or common cold virus, often is used asthe gene-delivery vector in gene ...

Mobile DNA sequences could be the cause of chromosomal mutations during the evolution of species

...elements,that are able to reproduce themselves and insert themselves freely in differentpoints of the chromosomes. Transposons were discovered some fifty years ago butthe implications of these with regard to cellular operations have only recentlybegun to be uncovered. The research team is made up of Mario ...

Scientists grow blood-producing stem cells outside the body

...hecorrected gene indefinitely. "If we can insert a normal gene into these dividing stem cells, we mayin many cases cure the disease," Bartelmez says. "One reason nobody has beenable to do this up until now is because no one can get stem cells to divideoutside the animal and just keep dividing. This...

Scientific team identifies gene critical in embryonic development

...y. The scientists then used an electric current to insert a piece ofDNA into those embryonic stem cells. The added portion of DNA integrated withthe cells' own genetic coding, causing the loss of the SIL gene. The stem cellswere then injected into normal mouse embryos and the resulting offspring wereused to...

Roundworm studies yield new insight into organ formation

... cells," said Kimble. The scientists also plan to insert the worm gene into other tissues in theworm itself in order to determine whether and how the enzyme affects organgrowth in those very different tissues. Such experiments may give further hintsof the enzyme's action and regulation, said Kimble. "Now ...

Genetic Stowaways May Contribute To Evolutionary Change: Adjacent Sequences Tag Along With Mobile DNA Elements, Study Shows

...able topick up flanking genetic sequences and then insert themselves and the tag-alongDNA at new locations. A report on the new study will appear in the March 5,1999, issue of Science. (Advance copies of the paper are available to reportersthrough the journal's news office at 202-326-6421.) "These f...

Brief Exposure To High Temperature Has Lasting Effect On Nervous System

...intact neuronal activity, but thinenough for us to insert measuring devices. To do this, we had to create a wholenew procedure for taking slices of the insect's brain, something that no one haddone before," says Ramirez. Cells in the slices were kept alive in a petri dish and Ramirezmonitored th...

University Of Chicago Professor Wins $50,000 Bristol-Myers Squibb Award For Distinguished Achievement In Infectious Disease Research

... the early 1970s.researchers gained the ability to insert or delete specific genes in manyorganisms and thus learn the gene's function. But the genome of HSV was too bigfor manipulation in the laboratory, so Dr. Roizman's group induced the virusitself to cut and paste genes into its own DNA. "We fo...

Gene Therapy Showing Promise In Fighting Melanoma

...h a "gene gun," a unique tool that helpsscientists insert genetic material into cells. With air pressure, the gun canshoot millions of microscopic gold beads coated with DNA into cells, which arethen injected back into the patient. In cells that are penetrated by the beads,the new genetic material becomes i...

Genetically-Altered Crops Can Produce Tough, Hard-To-Kill Weeds

...w. One solution might be for scientists to insert genetically-engineeredtraits into the DNA of the cytoplasm of plant cells, instead of the nucleus. The DNA from the nucleus gets into every pollen grain of a plant, and willtravel far and wide on the wind, or hitch a ride with pollinators such as bee...

New Hope On The Horizon For Patients With End-Stage Cardiovascular Disease

...ization (PTMR). Using thisprocedure, cardiologists insert a laser catheter into the heart, creatingmultiple channels from the inside of the heart, out. These channels improveblood flow to heart muscles and stimulate growth of new blood vessels. To date,four patients have undergone PTMR at Cedars-Sinai. Norm...

Lower Temperature Increases Virus Production

Genetic therapy requires retroviral vectors, which insert the "healthy" genes into the patient's DNA. The virus particles are normally produced at a temperature of 37oC. A team of molecular biologists in Leiden (funded by the NWO's Medical Sciences Division) have developed a method of increasing production ...

FDA Approves Hopkins-Designed Implants To Restore Lost Voices

...l cord. Using specially designedinstruments, they insert "sizers," or dummy devices of varying sizes and ask thepatients to speak. When the patient recognizes his or her "correct" voice, thephysicians remove the sizer and replace it with a same-size implant, locking itin place with a small shim of the sam...

Naturally Produced Enzyme May Be Useful In Inflammatory Arthritis

...olleagues suggest that gene therapy may be used to insert a gene that controlsNEP production. The extra levels of the enzyme could then degrade inflammation-causingpeptides and decrease damage and/or pain in joints. This concept is consistentwith the broader approach of stimulating natural substances...

Novel Method Of Gene Replacement Reported By University Of Washington Researchers

...truction booklet with an error in it,you'd want to insert the corrected instruction in the right place on the rightpage." The UW researchers' method guarantees that the new gene is controlled byappropriate genetic circuitry, ensuring that it is switched on in the rightcells, at the right time and a...

UPMC Researchers Report On Gene Therapy Advances

...heir study, researchers employed a viral vector to insert the genes into ananimal's cells. The cells then produced these healing substances both locallyand throughout the body. The researchers found that a single injection of cellscontaining the IL-1Ra gene led to decreased bone loss in the animal trials....

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