Tag: "inside" at biology news

Asian bird flu became highly pathogenic through continued circulation and gene swapping

...ct, the common human influenza H3N2 has been found inside pigs in southern China, according to the St. Jude researchers. If H5N1 infects a pig harboring H3N2, these two viruses might swap genes. The resulting "recombinant" virus might be particularly dangerous to humans, depending on which gene or genes it ...

Structure solved at Scripps shows how one human protein reduces potency of chemotherapy

...rtain chemotherapy drugs. AGT repairs damaged DNA inside human cells. Cancer cells can use it to repair DNA that has been damaged in the course of chemotherapythus rendering the chemotherapy ineffective. The structure of AGT, which is being reported in an upcoming issue of the journal Nature Structural &...

Mitochondria in spinal cords is ALS target according to UCSD medical researchers

...tend down the arms and legs. They found SOD1 both inside the mitochondria and coated on the mitochondria's ...yet which is the most damaging, the mutant protein inside the mitochondria or coated on the outside," Cleveland said. "This is part of our continuing work as...

Technology could enhance accuracy of breast biopsy

...ese chemical and structural features are intrinsic inside tissue," she says. "They're not things you have to add, so you don't have to add any dyes to make it work." Her group has built fiber-optic probes that doctors easily can thread down the existing hollow biopsy needle to the tip to help them find the ...

UCSD team determines cellular stress within body is critical

...olution outside of the cell is different than that inside the cell. When this happens, water flows either into or out of the cell by osmosis, thereby altering the intracellular environment. Hyperosmotic stress causes water to diffuse out of the cell, resulting in cell shrinkage, which can lead to DNA and ...

Protein controls acid in cells by direct detection of volume changes, study finds

...in and protons positively charged particles from inside the cell to escape and lower the cell's acidity. T...l, which allowed them better control over what was inside and outside of the cell. They also optimized the use of tiny sensors that can measure exactly the m...

Digital evolution reveals the many ways to get to diversity

...he bugs adapt and evolve in different environments inside their artificial world. Avida is the biologist's souped-up race car. To watch the evolution of most living organisms would require thousands of years without blinking. The digital bugs evolve at lightning speed, and they leave tracks for scientists...

The key to cell motility

...rols? All that was known until recently was that inside cells, Rac is controlled by a protein known as Rho...ationto attach phosphate groups to other molecules inside the cells in order to modify their function. Pak attaches its phosphate to two serine residues wit...

Basic RNA enzyme research promises single-molecule biosensors

...enzymes, RNA enzymes accelerate chemical reactions inside cells. Researchers want to learn how changes in ribozyme molecules affect their activity, both to better understand how evolution has shaped ribozymes to carry out their duties and to find ways of manipulating them for useful purposes. In the recent ...

A fly's taste experience is much like our own

...he taste. Though no one has mapped the taste areas inside mammal or human brains, other senses typically are...hey found that neurons in the mouthparts, that is, inside the proboscis, sent their information to the front part of the brain's subesophageal ganglion, neuro...

Targeted therapy for lung cancer patients shows promise in extending lives

...ial pathways within tumor cells, the therapy works inside of the cell with minimal effects on noncancerous cells. The drugs reduce the cancer by blocking the process by which cancer cells divide, grow and spread. Bonomi says that Tarceva "aims to slow cancer growth by blocking the action of a molecule calle...

Physicists reveal first 'nanoflowers'

...tal (Gallium) on a silicon surface, like the chips inside our home computers. The wires grow as a gas containing methane flows over the surface. The gas reacts at the surface of the droplets and condenses to form the wires. By changing the temperature and pressure of the growth process the wires can be con...

Newly grown kidneys can sustain life in rats

...tissue transplants can be used to grow new kidneys inside rats. In their latest study, though, they put the ...rking with embryonic tissues that grow into organs inside the patient lets Hammerman avoid hyperacute and acute vascular rejection, two immune system response...

New multidisciplinary research tops chemists' meeting Aug. 22-26

...deling DNA damage to actually studying that damage inside cells. From Huntington's disease to inflammation, DNA damage looks different close up, and the surprise findings could push the search for therapies in new directions. The ACS Divisions of Chemical Toxicology and Biological Chemistry are sponsoring t...

Salmonella infects cells and saves itself by altering host membrane lipids

...fed and digested by cells called macrophages. Once inside a macrophage, the bacteria are targeted for death by a mechanism that transports them within a vesicle to a specialized compartment, the lysozome, designed to degrade foreign or unwanted materials. Once the bacterium is engulfed, it takes only...

Espionage may have driven the evolution of bee language according to UCSD-led study in Brazil

...behind some bees' ability to conceal communication inside the hive, using a form of animal language to encod...bout distance and direction to a food source while inside the hive....

Study probes ecosystem of tree holes

...ther of the groups of species. 'It's war inside a tree hole," Kneitel said. "We found that predation has the strongest effect when there are no disturbances. Disturbance has the strongest effect when there is little predation. When there is no disturbance or predation, competition is the primary...

Scientists characterize new breast tumor subtypes with poor clinical outcomes

...genes and the proteins they represent lets us walk inside the building and see what's there - and exactly where we could intervene with a treatment." Dr. Perou's lab is known for its use of genomic approaches to classify human tumors and to understand pathways altered within each tumor subtype. He then w...

Breast cancer patients failed by treatment with taxol and taxotere respond to abraxane

...umor site in the body, and more of the drug to get inside of the tumor to fight cancer cells." The tolerability of the weekly regimen was demonstrated by the finding of <1 percent grade 4 febrile neutropenia and no grade 4 non-hematological toxicities. Grade 3 associated toxicities were few, with <...

How genes get us wired

...i agrees: "You are using the same gene outside and inside the brain to allow nerves to make the appropriate circuits. This may be true not only for nerves in the face, but for other Hox genes that help form nerves that control the body from head to foot." The study is being published in the June 15 onlin...

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