Researchers design and build first artificial protein
...ein structure prediction methodology. "Indeed, the integration of protein design algorithms (to identify low energy amino acid sequences for a fixed protein structure) with protein structure-prediction algorithms (which identify low energy protein structures for a fixed amino acid sequence) was a key ingredient ...Alcoholics with antisocial personality disorder have blunted emotional reactivity
...niversity and first author of the study. "Through integration with cognitive processes, emotional reactions play an important role in learning and memory, evaluating variable environmental contingencies, and motivating adaptive behavior. There is considerable variability among individuals in terms of how emoti...The American Society for Biochemistry and Molecular Biology meets in Boston
...ynamics, genomics, proteomics, and bioinformatics; integration of signaling mechanisms; molecular and cellular biology of lipids; molecular recognition and catalysis; protein modifications and turnover; protein structure, catalysis, and dynamics; regulation of gene expression and chromosome transactions; signali...New research technique provides clues into cell growth
...P activation but also could visualize the specific integration of PIP2 and CDC42 stimulation," Ward says. "This supports the idea that our probe is sensitive to normal cellular signaling processes." Using their new technique, the team recorded preliminary observations of N-WASP activation throughout living cells...Protein data bank opens new era with broader support
... one of its central challenges willbe the expanded integration of its wealth of information withother biological data, images and research articles. According to Kim Henrick of the European BioinformaticsInstitute, "The PDB must expand both in the storage andannotation of protein production information and into ...Making new muscle: Researchers in Rome produce a mouse that can regenerate its tissues
... functions in tissue. "Many labs have reported the integration of stem cells into various types of tissues, but on a small scale," says Prof. Nadia Rosenthal, Coordinator of EMBL's Mouse Programme in Monterotondo, Italy. "This is the first study to show that stem cells can be mobilized to achieve a major regener...European researchers launch 10 million euro collaborative technology project
...mission strives to support the development and the integration of the best technology at each step, and then spread that across all of the sites." Several new European synchrotrons, now on the drawing board or under construction, are scheduled to go on line by 2006 or 2007. BIOXHIT calls for them to begin using ...Powerful machines are coming in small packages
...the efficiency of fuel reforming, and microfluidic integration for improving the shelf-life of tissue-based sensors. "We're trying to take large amounts of fluids down through microchannels and then back out to affect the macroscale environment," Paul said. "These technologies are expected to revolutionize the w...Passwords to guard entry aren't enough to protect complex data
...d disables research, since long-term follow-up and integration of data from encounters at diverse sites are needed. Wiederhold says filters can and should check outgoing documents for terms warranting more protection. "When these [medical] and other databases are designed, the possible uses and security needs c...Human evolution at the crossroads: Integrating genetics and paleontology
...ed Sunday at a news briefing. Hlusko's call for an integration of paleontology and genetics is also the focus of ...said: recovery of new fossils (fieldwork); and the integration between genetics, development and paleontology. Speakers in the symposium who discussed their curren...Schering-Plough scientists identify protein essential for cholesterol absorption from intestine
...nt, SPRI. "This discovery reflects the successful integration of new technologies, including genomics and bioinformatics, into discovery research and scientific excellence by a team of SPRI scientists representing a variety of disciplines." "While research in the past few decades has contributed much to our und...UC San Diego faculty receive funding from von Liebig Center to commercialize academic research
...rts in the photonics industry see potential in the integration of Germanium-based optical components with conventional CMOS-based electronics, allowing for the development of opto-electronic integrated circuits with superior performance and functionality (compared to optical or electronic circuits alone). With ...World's first databank for all living systems
...ysical sciences. For example, the large-scale data integration will make it possible computationally to examine the effects of drug molecules on their environment and ecology. Cornell's wide-ranging experience in international education and research springs from its pioneer work in agricultural development in wh...Envisat concludes a busy second year in orbit
...hin 24 or 48 hours after satellite acquisition for integration into an operational and commercial service." Images of the year Throughout the last year Envisat has been returning a steady stream of striking images and scientific data showing the ever-changing face of our planet. Some of the most memorable re...NIEHS/NTP Director Dr. Kenneth Olden receives Society of Toxicology's Public Communications Award
...h research and has served as a model for effective integration and focusing of bench research on human and environmental health issuesHis ability to reach all audiences and tireless commitment to bettering the health of the public-at-large makes him one of our discipline's most effective advocate and communicato...Office Depot partners with Conservation Organizations to incorporate science into paper procurement
...olicy, also released today. The Alliance, and the integration of its objectives within Office Depot's Environmental Paper Procurement Policy, is the product of more than 10 months of collaboration, during which time the conservation science organizations worked with Office Depot to: v Identify the challenges ...Ferns diversified in shadow of flowering plants
...sperm fossils to currently existing lineages. "The integration of fossils with molecular phylogenetic data is an extremely powerful tool for identifying historical trends and events across the tree of life," Pryor said. "This approach permits the most comprehensive understanding of the past by combining informat...Imaging the brain solving problems through insight
...rred in RH aSTG suggests what that process may be: integration of distantly related information. Distinct neural processes, the authors conclude, underlie the sudden flash of insight that allows people to "see connections that previously eluded them."...Keck Futures Initiative announces grant recipients
... The goal of this project is to understand signal integration of multiple G protein pathways. The thrombin receptor, PAR1, is known to mediate its complex actions in the endothelium via its ability to couple to multiple G proteins: Gi, Gq and G12/13. To assist in the direction of their research and to encaps......cells. The combination of these signals and their integration by the ARC pacemaker is such a finely balanced mechanism that one small error or mutation leading to any inappropriate communication in these pathways could produce a significant untoward affect on human eating or feeding patterns. The high number o...