Nicotine may have another side effect: heavy drinking
...We need to better understand how these two drugs interact with oneanother. We need to better understand why these two drugs are co-abused, and to develop an effectivetreatment of that co-dependency." The remaining two experiments of the five in L's study looked at the use of nicotinic receptor antagonis...UCSF researcher reports on protein therapy to reverse facial birth defects
...irst understand the web of different proteins that interact and influence correct face and brain development. Researchers have learned that one central player is the sonic hedgehog protein, which is named after a video game character, and which directs aspects of limb growth and lung development. Vitamin A,...Revised model of protein-drug interactions could make job of drug designers a little easier
...ound a tetrahedral carbon atom at the business end interact with three locations in the active site, usually with such precision that no other alignment would work. In fact, Koshland and Mesecar say, a three-point landing is not sufficient to allow a protein to discriminate between mirror images of the incom...Proteins that bind to sperm offer clues to male fertility and possible male contraception
... and secreted into that tubule that might possibly interact with sperm in such a way to affect their maturation." Attempting to fill in the gaps in epididymis molecular biology and to find possible protein targets for male contraception, Hall and her colleagues at UNC's Laboratories of Reproductive Biology ...Light receptor may be key in how animals use Earth's magnetic field
... achieved in higher animals." Typical biomolecules interact with Earth's magnetic field too weakly to alter the course of their chemical reactions. In earlier experiments, Schulten had shown that certain chemical reactions involving so-called radical pairs can be influenced by weak magnetic fields, like that...A new way to engineer cells: The Staudinger ligation
...arkers. When these chemical probes were allowed to interact with the treated cells, the cells became intensely fluorescent -- the phosphines had found the azides. "We have developed a useful reaction based on a biological mandate: that the new markers and reagents must be abiotic and harmless to the cells,...Fruit fly's genome sequence finished in record time: Physical maps are the key to accuracy
... theidentification of networks of other genes that interact withknown disease genes, and their associated metabolic pathways. Theimplications for medicine are immediate. To this end the BDGP researchers are continuing to refine the D.melanogaster sequence already produced. "We're going to push itto high accur...Understanding how the first cells emerged
...s simulated what happens to M2 molecules when they interact with simple membranes made of a mixture of organic substances such as carboxylic acids. Such membranes can spontaneously form vesicles reminiscent of cells (New Scientist, 12 September 1998, p 30). The M2 protein has a water-loving backbone and oily...The genetics of aging: New study says cell division errors may be the common link
...s to better understand the importance of how genes interact with each other. Some believe that gene interactio...d broader analyses of how genes function, how they interact with one another and with the environment. This research will bring us closer to identifying specifi...First awards made in NIH effort to understand how genes affect people's responses to medicines
...per" molecules called membrane transporters, which interact with a third of the most commonly used prescription drugs. University of California, Los Angeles (Julio Licinio, M.D., principal investigator)--$285,000 provided by NIGMS for a one-year pilot project to search for genetic differences that play a ro...Nerve protein shown crucial to sensations of pain from heat, injury
... This probably reflects theinability of protons to interact with the capsaicin receptor, the researchersconclude, and suggests that blocking the receptor with a drug could controlsome kinds of pain. The research provides one of the first molecular pieces in the puzzle of painsensation, Julius says. While much...Gene defects tied to inability of cells to repair DNA damage
... From numerous studies, free radicals are known to interact readily with nearby molecules to cause cellular da...ularly a mutation occurring in a region where they interact -- may lead to disease expression.The study also suggests the importance of this repair process to d...Give it a thought -- and make it so
...eople, robot-like actors with which volunteers can interact in a limited way. So in the future will we all be wearing little caps that will let us open doors, channel surf and drive the car on a whim? "Not likely," Bayliss says. "Anything you can do with your brain can be done a lot faster, cheaper and easier...Chemical discovered that causes plant tumors
... actually works to the benefit of the insects that interact with these plants, Doss said, so in various natural systems it's not clear that there is any single evolutionary explanation for the formation of these tumors. The discovery of basic plant growth mechanisms can have important implications, the scien...DFG to launch 21 new priority programmes
...entists examine how ultra-cold atoms and molecules interact and how their inner and outer degrees of freedom can be specifically manipulated. Some examples of application areas are atom lasers, atomic clocks or instruments with which the Earth's gravity can be accurately measured. Thanks to a number of space......r are now studying how other transcription factors interact with PU.1 to control the development of immune cells. "Different levels of PU.1 is just one piece of the equation," says Singh. "There are several other transcription factors that work in concert with PU.1 to regulate the differentiation of blood c...Discovery shows how brain 'fills in blanks' to help us see
...nto have discovered how the brain helps us see and interact with objects by filling in missing information, according to a study published in the June issue of Current Biology. Because most of what people see is often blocked by other objects, the visual information received by the brain is usually incomplete...Genomics project aims to create a "virtual plant"
...a broader understanding of how these gene networks interact with one another to build cells and tissues. Finally by 2010, plant researchers hope to construct a complete "wiring diagram" of all the biological pathways of Arabidopsis . "Ultimately, we hope to create a 'clickable plant,'" said Chory. "We want...Researchers develop tastier low-fat cheddar
...w-fat cheeses, fewer fat globules are available to interact with or mask such compounds. While their prevalenc...of the bacterial micro-organisms, and the way they interact during cooking, release certain enzymes that appear to degrade or destroy substances that your taste...Researchers decipher chemical 'cross talk' that determines survival of immunecells
...ng sites could provide a window on the way signals interact to direct gene activity. The interaction is complex. A strong signal from either the glucocorticoid receptor or the T cell receptor -- in the absence of the other -- kills immature and some mature T cells. But together, the two signals rescue T cel...