Bacterial Toxin Surprises Scientists
...rove general understanding of the critical interactions between proteins and membranes. Please acknowledge partial funding for this work from the National Institute of General Medical Sciences (NIGMS), a component of the National Institutes of Health that supports basic, non-dise...New Cancer Switch Discovered By Duke Medical Center Pharmacologists
...s. "These results suggest that inhibition of GRB-2 interactions may provide a useful therapeutic target for treatment of [chronic myelogenous leukemia] as well as other tyrosine kinase-associated human cancers such as breast, ovarian, glioma, squamous cell carcinoma and leukemia," the scientists wrote. According ...Researchers Corral Millions Of Microscopic Membranes
...o perform key research regarding the nature of the interactions between cells. Groves began working with supported bilayers in 1994. His first discovery was that scoring supported membranes with a pair of tweezers caused them to separate permanently. He took advantage of this characteristic to partition the membr...Stronger Evidence That Global Climate Change Can Reduce The Variety Of Life
...nts and temperatures.Competitive and predator-prey interactions among species may also bedisturbed by limited food resources and changes in bottom watertemperatures....Scientists Determine 3-D Crystal Structure Of Cancer-Causing Protein
...(SH)domain 2, is a signaling molecule that enables interactions and containsdocking units. Normally, Hck, like the other members of the Src family, is"off," folded into a position much like a snake biting its own tail. In thisclosed position, SH2 binds to the phosphotyrosine in Hck's tail, but if thisphosphotyros...Enzymes Targeted As Key To Understanding Drug Interactions
...ol of Pharmacy researchers investigating such drug interactions for more than a decade. "There are simple test-tu...lp health care professionals manage potential drug interactions in their patients. "There has been much publicity on the bad news about drug interactions," Levy sa......dwell. They collected data for some 16 yearson the interactions of two insect species, the winter moth andthe green oak leaf roller moth, that feed on English oaks inWytham Woods near Oxford, England. The research published by Varley and Gradwell has long beenconsidered a classic of population ecology. And y...Scientists To Study Effects Of Global Warming On Wetlands
...The major objective of the study is to examine the interactions betweenplant community composition and dynamics, whole-ecosystem carbon exchange, and the radiative and thermal energy balance of northern peatlands under a changing climate. "The central hypothesis," said Chen, "is that climate caused heatlo...Hunt For Early Heart Attack Genes Begins
...om a person's complex genetic makeup andhis or her interactions with the environment including what he or she eats, howmuch he or she exercises and if he or she smokes. While we know a great dealabout the influence of diet, exercise and cigarettes on heart disease, we do notyet know the identity of genes that wo...Regulator Of Fat Thermostat Found
...nd to leptin, though little isknown about leptin's interactions in the body. Now investigators at Washington University School of Medicine in St. Louis haveidentified the first factor to significantly boost human leptin concentrations.And surprisingly, this substance also boosted leptin levels in some overweight...Increased Amount Of Enzyme In Brain May Be Marker Of Alzheimer's Disease
...isease-causing state remain unknown and mayinvolve interactions with additional plaque constituents, he said. Among these constituents are a number of "companion" molecules, e.g.,apolipoprotein E, complement factors, acetylcholinesterase, BChE and others.Mesulam and colleagues believe that some of these ...3-D Structure Of HIV Components May Pave The Way For New Anti-AIDS Drugs
...ral interaction iscompletely different from normal interactions in human cells. This indicatesthat such custom-designed drugs may not only stop viral spread, but also couldbe safe for patients. The Summers and Borer groups also have determined the structures of the isolatedprotein and RNA components. Because ...Memorial Sloan-Kettering Investigators
... interact with other proteins. In PML- RAR , these interactions were broken apart by RA,while in PLZF-RAR they were insensitive to RA, explaining why retinoic acidworks in some APL patients but not others. Armed with this new knowledge, the MSKCC researchers set out to findways to undo this chain of even...USGS Cautions Proper Use Of Pepper Spray To Avoid Bear Attacks
... spray as a bear deterrent inaggressive bear-human interactions fax Dr. S. Herrero in Calgary, Alberta,Canada, at 403-284-4399. S. Herrero and A. Higgins. 1998. Field use of capsicum spray as a beardeterrent. International Conference on Bear Research and Management. In press. This press release and in-depth in...Plants Thrive With Insect-Induced Immune Responses
...vis professor of entomology and anauthority on the interactions between insects and their host plants. The study was conducted using wild radish [Raphanus sativus L. (brassicacea)]as an experimental model. The plant is a member of the mustard family, membersof which are found in most parts of the world. Agrawal...Pet-Owning Couples Are Closer, Interact More Than Pet-Less Couples, UB Study Shows
...and those most attached to their pets had the most interactions with their spouses, according to the findings. ... study. "We know that people who have many social interactions are healthier than people who don't. In this study, people who owned pets had significantly more in......en demonstrated. Kinetics of biomolecular interactions like nucleic acid hybridization or protein aggregation were previously investigated by Eigen and coworkers applying dual-color FCS. Now, it has been extended to real-time analyses of enzyme kinetics. As a first application, the kinetic pa...Study Finds Russian Women, Children Not Getting Enough Iron In Their Diets
...e than half the ironthey do ingest is lost through interactions with other foods. Scientists at the University of North Carolina at Chapel Hill conductedthe research, sponsored by the U.S. Agency for International Development, withseveral Russian academic and government institutions. It involved analyzing...Bison Grazing Increases Biodiversity In Grasslands
...y, nitrogen availability in prairies was driven by interactions between frequency of fires and grazing by large herbivores. In general, spring fires enhance growth of certain grasses, and herbivores such as bison preferentially graze these grasses, keeping a system of checks and balances working properly, and al...The First Rejection: Eggs Sequester Bits Of Sperm For Later Elimination
...who have been studying the often bizarre sperm-egg interactions of Drosophila for several years, previously notic... indicates that "previously unrecognized sperm-egg interactions are important to the success of a developing zygote," says Karr. One intriguing possibility, he sugg...