Tag: "intestine" at biology news

Researchers Find Genetic Clues To Intestinal Disease

... disease, which causes painful inflammation of the intestine and severe diarrhea, may appear in one of three fo... symptoms, it tends to strike the same part of the intestine and cause the same symptoms in close relatives who have inherited the disease.This suggests the dise...

Erodible plastic microspheres could be effective oral drug delivery system

...was incorporated into cells of the liver and small intestine andproduced an active protein within five days. Moreover, use of the microspheres greatly enhanced the drugs' availabilityin the bloodstream. For example, the increase in activity of dicumarol could beexplained by intestinal uptake of up to 47 perc...

Finished Your Lunch? Now Eat The Wrapper

...gestivetract to arrive largely intact in the large intestine (or colon), whereit had a number of significant health benefits. Dr Topping says scientists did not at first fully appreciate why resistantstarch was so good for the colon. However, earlier research in pigs hadshown it dramatically promoted the grow...

Many Dog Foods About Equal In Nutritional Value, Researchers Say

...cts were only slightly less digestiblein the small intestine than was food with raw poultry. Overall, by-productsin feed are good sources of digestible nutrients, the authors concluded. The poultry by-product effect, Fahey said, probably resulted from extraneousmaterial, such as feathers and egg shells being...

Human Breast Milk Contains Obesity Hormone

...e know there is a mechanism for it to get from the intestine to the bloodstream." No one knows yet if leptin is present in cow's milk, or if the pasteurization process damages the hormone, Houseknecht adds. Researchers don't know whether leptin offers any advantages or disadvantages for infant developm...

Gene For Inherited Syndrome Is Possible New Tumor Suppressor

...is characterized by theoccurrence of polyps in the intestine that are oftenpremalignant, and by the presence of peculiar freckle-like spots on the lips andthe skin around the mouth and on the fingers.How these two relate to each other is absolutely unknown." Furthermore, he said, "the combination of tumors tha...

Scientists Identify Protein Essential For Iron Absorption, Boost Understanding Of Iron-Deficiency Anemia

...specifically responsible for ironabsorption in the intestine and iron traffic within cells, have long eludedresearchers. The researchers said their results demonstrate that the protein isimplicated in at least two, and probably three, important functions in ironmetabolism. "The...

Lactose-Intolerant People Should Drink More Milk, Expert Says

...a meal, they tend to be transported throughout the intestine more rapidly and are more likely to cause symptoms...ave shown a really amazing adaptation of the large intestine of humans," Savaiano says. "The large intestines contain bacteria that help digest lactose. By alter...

Breakthrough In Understanding The Biology Of Fat-- UCSF/Gladstone Scientists Discover Gene For Key Enzyme

... found large amounts of DGAT geneexpression in the intestine and in fat tissue--indicating that these mousetissues are where significant amounts of DGAT are made. "These sites areconsistent with a role for DGAT in fat metabolism," said Cases, a postdoctoralfellow who is first author of the study. In ad...

Scientists Find First Protein In Central Nervous System Junctions

...olybdenum cofactordeficiency by assaying liver and intestine for two unrelatedmolybdenum-requiring enzymes. Neither was active in the gephyrin-deficient mice. The researchers also showed that the spasticity ofthese mutants really did result from a lack of inhibitory synapses in the spinalcord as well as from m...

New Discovery Offers Hope For Controlling Cholesterol, Atherosclerosis

...osis Scientists have found a protein in the small intestine that may force medicalscience tore-think long-held...umed thatsuch lipidssimply diffused from the small intestine into the blood stream, a process thatis verydifficult to control. Researchers say the newly discove...

Search For Iron Transport Mechanism Leads To "Hephaestus," God Of Metal Working,Who Insight Into Iron-Deficiency Anemia

...m contributes to blockedtransport of iron from the intestine to the gut. "We've discovered a homologue to ceruloplasmin that is located specifically inthe intestines," said Vulpe, "Hephaestin probably needs copper just likeceruloplasmin to do its job of iron export." This is fitting, he explained, taking the o...

Genes Linked To Early Onset, Location Of Hereditary Colon Cancer

...e patients develop in the distal area of the large intestine (that is, regions closer to the rectum) rather than in regions closer to the large intestine's junction with the small intestine, which is more typical. The genes identified by the researchers are all involved in the detoxification of cancer-causing ...

Allelix Clones Receptor For Intestinal Growth Factor GLP-2

...ell growth may be a useful adjunct fortreating the intestine in the presence of active inflammation," noted Dr.Drucker. Allelix's ALX-0600 is an analog of human GLP-2 that is approximately three timesmore potent than native GLP-2 in a mouse model of intestinal epithelial cellgrowth activity. Several academic r...

Genetic Research Boosts Understanding Of Iron's Path Through Body, Diseases Of Iron Metabolism

...y, which proteins control how muchdietary iron the intestine absorbs, Andrews adds. The mutant mice have lowlev...ell surface. Without the transferrin receptor, the intestine inthe mutant mice may never "know" about the lack of iron in the body's cells. But the tran...

Findings Challenge Notion Of Withholding Food To Fight Rotavirus

...rinarypathobiologists compared the activity of the intestine of healthy neonatal pigswith those that were infec... suggest thatoral nutrients may be required by the intestine to maintain structural integrityand for the development of local immunecomponents. The studies suppo...

Bugs Can Ward Off The 'Bends'

...e yogurt. "Theseare microbes that you have in your intestine right now," he says. The treatedpigs seemed to suffer no ill effects and their altered gut microflora laterreturned to normal. Lawrence Martin, a specialist in diving medicine at the Mount Sinai MedicalCenter in Cleveland, Ohio, describes Kayar's ap...

Studies Of A Gene For A Rare Form Of Rickets Shed Light On Vitamin D Deficiencies

...e is toregulate the absorption of calcium from the intestine into the blood and thedeposition of calcium into bone. Without it, adult bones become brittle andchildren's bones do not grow. The calcitrol-calcium combination also isnecessary to aid nerve growth and muscle function. "Work with the gene has provid...

Discovery Of A Molecule That Controls Bile Acids May Lead To New Cholesterol Drugs

...ve that I-BABPtransports the bile acid through the intestine wall. Other UT Southwestern researchers involved in the study were Dr. Makoto"Mac" Makishima and Joyce Repa, HHMI associates. This was a collaborative effortwith scientists from Tularik Inc. in San Francisco. A grant from the Rober...

Scientists dissect bacterial crosstalk

...gar, a hungry bacteriumsays. And the lining of the intestine complies. But how can microbes talk tomammals' Wit...etaiotaomicron. So the bacterium somehow tells the intestine to give it food.And the researchers have found the molecular switch. First, Hooper created mutants ...

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