New study may explain how fats damage neurons in Alzheimer's patients
...ce of the disease in people with Alzheimer's. "The involvement of cholesterol and ceramide in the neurotoxic actions of beta amyloid, and their strong associations with the way the Alzheimer's progresses, suggests a novel approach for therapeutic interventions," Mattson said. "Our work suggests that dietary modi...Local, regional governments could take lead in curbing global air pollution
...s and cities are doing a lot." Local and regional involvement in solving problems with global resources is the focus of Dolak's presentation Friday during a symposium on the international transport of air pollution, held at the American Association for the Advancement of Science meeting in Seattle. She noted t...Conservation International & Starbucks expand partnership, launch Verde Ventures loan program
...s are reflected through its supply efforts and our involvement with Verde Ventures demonstrates our desire to address the pressing issues that coffee farmers face today," said Orin Smith, president and ceo of Starbucks Coffee Company. "We hope that farmers will utilize their loans for conservation coffee product...Researchers find an association between alcohol dependence and the GABAA receptor gene GABRG3
...ervous system. Previous research has suggested the involvement of GABAA receptor genes in alcohol use and abuse. New research has found that one GABAA receptor gene in particular, GABRG3, has a consistent association with alcohol dependence. Gamma-amino butyric acid (GABA) is the major inhibitory neurotransmitt...JCI table of contents, December 15 2003
...g polychondritis with a high disease incidence and involvement of multiple organs that will be useful for studying autoantigens and regulatory cells involved in the pathogenesis of this disease. TITLE: Auricular chondritis in NOD.DQ8.Abo (Ag7/) transgenic mice resembles human relapsing polychondritis AU...Gene interactions control circadian clock in plants, study finds
...ns gave the researchers information on each gene's involvement in regulating the circadian clock. "We wanted to know what keeps a plant's circadian clock running at the right speed," Somers said. A faulty TOC1 gene caused the plants to run on a faster schedule their circadian clocks had sped up to 20 hours. Con...Call for Entries: The 2004 Wistar Institute Science Journalism Award
...ts. Employees of The Wistar Institute will have no involvement in the judging process. The members of the 2004 Wistar Institute Science Journalism Award judging committee are: Deborah Blum (co-chair) Professor of Journalism University of Wisconsin-Madison Winner, 1992 Pulitzer Prize Joe Palca (co-chair) Senior S...A new hope for heavy metal contaminated soils
...undant. The researchers could again demonstrate an involvement in zinc detoxification. Furthermore the messages for several membrane proteins are highly abundant. One of these is likely to have a function in metal transport into shoot cells. The other two proteins are involved in the detoxification of zinc ions....The dopamine receptor D1 gene and ADHD: A piece of the genetic puzzle?
...e dopamine system are considered as candidates for involvement in the disorder. Genes that have been investigate...udies, to date, have found strong evidence for the involvement of two of these receptor genes, those encoding the D4 and D5 receptors, but little or no evidence fo...Findings offer clue to how molecule can both stimulate, suppress cell growth
...OCK signaling pathway, traditionally known for its involvement in cell differentiation and defining cell shape, plays a key role in TGF-b inhibition of cell growth. "Perhaps inactivation of this pathway is a way that cancer cells override the normal growth-suppressing activity of TGF-b," Bhowmick said. More wor...Story tips from the Department of Energy's Oak Ridge National Laboratory
...te. A final goal is to develop a protocol with the involvement of regulators and stakeholders. The Department of Energy funds the three-year project led by the Savannah River Technology Center. [Contact: Ron Walli, (865) 576-0226; wallira@ornl ....First-ever UN University diploma offered to grads of online water-management course
...; domestic and international governance, community involvement and gender issues Course 9: Organizational infrastructure and management The issues, concerns and approaches to finance, budget, infrastructure, management and planning, as well as public health administration and project management. Course #10: Appl...Cell death promotes learning growth
...cognitive disturbances. In order to understand the involvement of the hippocampal formation in the mediation of normal and pathological behaviors, much attention has recently been devoted to hippocampal neurogenesis. The dentate gyrus of the hippocampal formation has the ability to generate new neurons throughou...International collaborators to form the Worldwide Protein Data Bank
... PDB, it is a natural step for us to formalize our involvement through the wwPDB." The PDB is the single archive of biological macromolecular structure data, which is made freely and publicly available to researchers, educators, and students. Worldwide, the PDB receives over 60 million hits per year. As of Oct...Brain's 'master molecule' produces same behavior in mice from three different psychostimulant drugs
...fferent mutant mouse lines, implicating a critical involvement of two distinct, but interacting, phosphorylation sites of DARPP-32 in the actions of LSD, PCP and amphetamine, says Svenningsson. Ongoing research is aimed at further understanding how DARPP-32 can process a wide variety of neurotransmitters that a...Social mothers appear to be better mothers
...e that there's a link between the amount of social involvement and having offspring who survive the critical first year of life." The connection is noteworthy because "reproductive success is the gold standard in evolutionary biology," said Silk, an anthropology professor in UCLA College. "A trait can't really b...Work begins on powering a sustainable future for the UK
...d impact of the work. It is also expected that the involvement of Carbon Vision with SUPERGEN will help take forward the recommendation made in the Energy White paper on the need to build closer links with industry. The Carbon Vision partnership between the Carbon Trust and the Engineering and Physical Sciences ...NHGRI selects sequencing centers
...ative agreements in which substantial programmatic involvement is anticipated among NHGRI and the recipients during performance of the scientific activities. Funding levels for FY 2005 and 2006 are planned to be $163 million and $133 million respectively. The NHGRI-supported, large-scale sequencing centers, the...Herpes research uncovers possible clue to Alzheimer's disease
...shnan. Questions persist, however, as to what that involvement is, and why, when APP is found in all of us, it causes problems only in a few. Perhaps, Bearer speculates, when the APP is co-opted by the herpes virus, the APP breaks down at a location where it would not normally appear and at a very different rat...Embryonic pathway critical to growth of digestive tract tumors
... cancer, providing reason to anticipate Hedgehog's involvement in a variety of other cancers, notes Berman. "Because of Hedgehog's important roles in these tissues during development, we hypothesized that 'reactivation' of the pathway occurs in adult life during cancer development in these organs," adds Maitra, ...