Tag: "ion" at biology news
New way to protect brain from stroke damage
... implicates a recently described class of membrane ion
channels, called acid-sensing ion
channels (ASICs), to the influx of calcium in nerve cells starved of oxygen and subjected to acidic ...
News tips from the Journal of Neuroscience
...rons of the suprachiasmatic nucleus (SCN). Several ion
channels, including L-type calcium channels, Ih, and subthreshold TTX-sensitive sodium channels, have been nominated for the spontaneous interspike "pacemaker" current that drives spontaneous firing. To distinguish between these candidates, Jackson e...
Cell's gatekeeper for ammonia revealed in unprecedented detail
...upts central nervous system function when ammonium ion
concentrations are elevated, research shows, so the channel's high efficiency is vital. Each channel threads in and out of the cell membrane 11 times and is structured so that no ammonium ion, NH4+, nor any other ion, can pass through. As NH4+ enters...
Commercialization deal boosts hope for new sickle-cell drug
...azole prevents red-cell dehydration by blocking an ion
channel, known as the Gardos channel, through whic...arch Triangle Park, N.C. Icagen, which focuses on ion
channels as drug targets, did further chemical work to optimize the drug and sponsored Phase I and P...
Epilepsy: Signals 'brake' in brain impaired
...erve cells (neurons) is altered: normally specific ion
channels absorb the neuronal activity. In rats suf...ke seems impaired: they have far fewer functioning ion
channels than healthyrats. The results are published in the latest edition of the prestigious scient...
ORNL adds three R&D 100s to DOE lab-leading total
... created by ORNL uses a process known as selective ion
exchange, which is the preferred treatment technol...ult is an 80 percent reduction in costs over other ion
exchange procedures and elimination of the problem of secondary waste. Advanced Heating System for ...
Physics tip sheet #42
...one of each. In this experiment, a trapped cadmium ion
in an excited state decays by one of several possible decay paths, emitting a photon that carries off information about the state of the de-excited atom. This is the first observation of entanglement between stationary and "flying' qubits. (Paper G2 ...
Animal studies show promise treating severe chronic pain
...pore, but only in those cells that manufacture the ion
channel. Three years ago, Iadarola's group published data showing the RTX-induced flow of calcium can overdose, seriously disable, and ultimately kill these neurons. Because nerve cells in the peripheral nervous system first transmit their signals t...
Tracking cystic fibrosis with mice
...tor" gene (CFTR), Mall's group focussed on certain ion
channels. These channels transport sodium ions thr...ry tract is no longer possible. Mice, whose sodium ion
channels had been altered, became ill with the lung inflammation typical of cystic fibrosis. The res...
Searle Scholars program awards $240,000 to UT Southwestern researcher
...cuses on determining the structure and function of ion
channels, which are proteins found in cell membranes. Ion channels control the flow of ions, such as sodium, potassium and calcium, across the cell membrane. Their function underlies many biological processes, including the excitation of nerve and mu...
Decoding a sulfate-breathing bug
...defining genes of interest in the process of metal ion
reduction and metal ion
precipitation is expected to help scientists find ways to use D. vulgaris or similar sulfate-reduci...
Gene-rich human Chromosome 19 sequence completed
...eins are chains of amino acids that capture a zinc ion
and bind to RNA or DNA and play a critical role in a cells life cycle. These proteins regulate the expression of genes as well as nucleic acid recognition, reverse transcription, and virus assembly. Drug development efforts seek to disrupt these zinc...
Spying on the inner life of a cell - new nanosensors a body can live with
...at we're trying to do at this point is incorporate ion
channels as detectors," Aspinwall said. An ion
channel is a molecule that moves a specific kind of ion
by opening or closing in response to the pre...
Scripps Research scientists find deafness gene's function
...cal change creates an electrical change and causes ion
channels to open. The opening of these channels is...ansmission of physical force to mechanically gated ion
channels. For years, the molecules that make up the tip link were not known. Now Mueller and his col...
Optically recording millisecond brain nerve impulses
...se, traveling through a neuron as chemically gated ion
channels open and close with changes in electrical polarity. The quantum physical optics phenomenon, second-harmonic generation (SHG) is the first multiphoton technique capable of detecting action potentials. SHG is particularly useful for imaging th...
Pacific Northwest National Lab unveils most complete human blood-plasma proteome map to date
...s spectrometry for this purpose: Fourier transform ion
cyclotron resonance (FTICR). PNNL's instrumentation can ransack a sample for proteins that defy detection by other means, having recently pushed the detection limits to about 10 zeptomoles, or on the order of 6,000 individual molecules, "allowing the...
Report details growing climate change threat to coral reefs
... cause an estimated 30% reduction in the carbonate ion
concentration in the upper ocean and affect both skeletal growth rates and the structural growth of reefs. "Coral reef ecosystems are going to be significantly impacted by climate change," Kleypas says. "They're already being degraded by both climate...
Researchers reveal calcium transport protein function that regulates heartbeat frequency, strength
...e patch" techniques together with highly sensitive ion
detection techniques, both developed and implement...e able to determine precisely how NCX1 works as an ion
exchanger, how many calcium and sodium ions move across the membrane, when they are exchanged, and, ...
UI researchers discover new activity in cystic fibrosis protein
... energy from ATP is not required to fuel any other ion
channel. The UI study now reveals that CFTR can function as an adenylate kinase enzyme. Like an ATPase, the adenylate kinase reaction uses ATP. But in contrast to an ATPase, an adenylate kinase enzyme also uses a related molecule called AMP. Import...
OHSU-led research examines role of copper, iron in diseases
...." Vital to the project's success is the "metal ion
core," a collection of precision lab equipment tha...'s OGI School of Science & Engineering and a metal ion
project investigator, is studying the interaction between the chaperones and target proteins, a syst...
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