St. Jude researchers reverse blood disease using genetically modified stem cells
...r late teens. But unless they are also treated for iron overload from blood transfusions they will eventually succumb to heart failure. In sickle cell disease, an abnormal gene for beta-globin causes hemoglobin molecules in the red blood cell to clump together and distort the cell into the shape of a sic...What makes the body absorb too much iron?
Like most nutrients, iron is good for people in the right doses. When the b...nding of how hemochromatosis develops. "Untreated iron overload can result in liver cancer, heart disease, or other fatal conditions," says Martina Muckent...Folic acid-iron supplements reduce risk of low birth weight
...le micronutrient supplement containing folic acid, iron and zinc and 11 other micronutrients. All particip...ndings showed that supplementation with folic-acid iron reduced the incidence of low birth weight by 16 percent and the multiple micronutrient supplements r...A closer look yields new clues to why bacteria stick to things
...ears, scientists have noted that bacteria stick to iron particles in soil, but not to sand grains. Until r...ely charged bacteria, while the positively charged iron attracted them. However, Campen and his adviser, James Kubicki, assistant professor of geosciences,...U-Iowa scientists gain insight on how enzyme uses oxygen to produce useful chemicals
...e always thought that side-on binding of oxygen to iron existed, but no one had ever seen it in this enzym...roject focused on how oxygen specifically binds to iron in the enzyme. Side-on refers to the newly visualized orientation of oxygen as it binds to iron. The...Discovery of iron-acquisition pathway suggests new treatments for drug-resistant Staph. infections
...of life-threatening infections, manages to acquire iron from its host's red blood cells, a critical step i...evelop drugs that would disrupt the Staphylococcal iron uptake systems," said co-author Eric Skaar, Ph.D., research associate in molecular genetics and cell...Using sewage sludge as fertilizer
...er. Some minerals such as phosphorus, calcium, and iron were higher in crops fertilized with sludge. In a very dry year, the water in liquid sludge can also enable nutrients to reach the crops rooting zone more effectively than synthetic fertilizer. Liquid sludge if processed and applied according to spe...Iron overload gene tied to colon cancer increased risk
...ith gene mutations associated with abnormally high iron levels are 40 percent more likely than others to d...e consistent with the view that taking in too much iron may be an environmental risk factor for colon cancer in some people," said study lead author Dr. Nic...Too much grape juice could cause iron deficiency
...is the first comparative analysis among juices for iron uptake ability. The journal is published by the Am...world's largest scientific society. While reducing iron can be beneficial for adults with certain medical conditions that involve excess iron, the same isn'...Revolutionary new theory for origins of life on Earth
... from inorganic incubators - small compartments in iron sulphide rocks. The new theory radically departs ...s were not living cells but inorganic ones made of iron sulphide and were formed not at the earth's surface but in total darkness at the bottom of the ocean...UMass team to study bioremediation of acid, heavy metals from collapsed mind
...nvironment or the area's water supply, because the iron sulfide in the Davis Mine contains few hazardous impurities. This makes the site an ideal subject for examining the natural processes that are contained in the drainage. Rowe is located in western Massachusetts, near the Vermont border. The other ...Scripps research gives tiny phytoplankton a large role in Earth's climate system
...ean, which would probably be a consequence of this iron fertilization, instead you would contribute to warming the ocean by absorbing more radiation," said Frouin. "You would exert a negative feedback because you would go in the opposite direction of the effect that you want, which is to decrease global w...Evolution upset: Oxygen-making microbes came last, not first
...ia and comparing it to the geochemistry of ancient iron and sulfur deposits, Carrine Blank of Washington U...ecules. All that oxygen bound to the abundant free iron in the oceans and rained to the seafloor creating the economically important banded iron formations...Asian dust storm causes plankton to bloom in the North Pacific
...the region was also limited by a lack of dissolved iron in the water. The Carbon Observers would soon put ...and February 2002 have proved by pouring dissolved iron into HNLC areas in the Southern Hemisphere. But prior to the spring of 2001, fertilization by iron t...Food for thought: What are the likely side effects of fertilizing phytoplankton with iron?
...in Mainz, Germany, has pointed out that the use of iron fertilization of oceanic phytoplankton as a means ...toplankton (algae) blooms with soluble iron, since iron is the limiting factor for phytoplankton growth in certain oceanic regions. The additional phytoplan...NSF awards $37.9 million in grants to study biocomplexity in the environment
...ted arsenic concentrations; and biogeochemistry of iron and sulfate reduction in extreme acidic environments. GENEN awardees will conduct research in such areas as: the interaction of viral genomes with the marine environment; analysis of factors determining the ecological function and resilience of mic...JCI table of contents: October 1, 2002
...*************************** The gene encoding the iron regulatory peptide hepcidin is regulated by anemia...tical for human health. As mammals cannot regulate iron excretion, homeostasis depends on the regulation of dietary iron absorption in the duodenum in respo...Tiny, magnetic spheres may help overcome gene therapy hurdle
...rospheres, each containing a miniscule particle of iron oxide. Using a magnet placed under culture dishes,...ht properties," he said. "They have to have enough iron oxide to be pulled by the magnetic field, and you have to make sure they have the right rate of degr...Big-bottomed sheep have a rare genetic mutation that builds muscle, not fat
...of the study. "These sheep are, in effect, pumping iron without lifting weights," explained Jirtle. "They are converting food into muscle in their hind regions, instead of converting food into fat." Results of the study, funded by the USDA and the National Institutes of Health, are published in the Octob......ered it neatly performs a chemical mambo that uses iron and oxygen to burn off the renegade methyl group. What's left at the end of oxidation is formaldehyde. The British part of the team Sarah Trewick, Tomas Lindahl and Barbara Sedgwick, confirmed repair of the DNA, allowing survival of the cells. "I...