Landmark gene agreement announced by Samoan government and UC Berkeley for anti-AIDS drug Prostratin
... signed an agreement with the Samoan government to isolate from an indigenous tree the gene for a promising a...y of California as a full partner in the effort to isolate the Prostratin genes." Despite Prostratin's promise as an anti-AIDS drug, its supply is limited by ...Landmark agreement between Samoa and UC Berkeley could help search for AIDS cure
... signed an agreement with the Samoan government to isolate from an indigenous tree the gene for a promising a...y of California as a full partner in the effort to isolate the Prostratin genes." Despite Prostratin's promise as an anti-AIDS drug, its supply is limited by ...New molecular link key to cellular proteins involved in cancer progression, other diseases
...smaller fractions, the UNC scientists were able to isolate and identify the proteins involved in H2A ubiquitination. "To our surprise, it happened to be one of the Polycomb-group proteins," said Zhang. "We've uncovered a new mechanism used by these well-characterized proteins." The new findings have implicat...DNA barcode finds four new bird species
...ity of Guelph showed that the COI gene was easy to isolate from a variety of animals, and that species in a broad range of animal life, from flatworms to vertebrates, have distinct COI sequences. "The genetic barcoding technique developed by Paul Hebert and used in the PLoS Biology paper is the l...Green, leafy spinach may soon power cellphones and laptops
...inary spinach and purified it with a centrifuge to isolate a protein deep within the cell. The resulting dark green pellets that smell like cut grass were purified still further and coaxed into a water-soluble state. One of the challenges was to keep the proteins in the same configuration as they appear natu...Chemical genetics identifies SARS inhibitors
...f Hong Kong conducted a chemical genetic screen to isolate compounds with anti-SARS-CoV activity. The group screened an initial library of 50,240 compounds and found that 104 were potent inhibitors of the virus; of these, two targeted the virus protease specifically, seven targeted the helicase, and 18 targe...Maine-based biophysics institute gets funding for first US-based 4Pi nanoscale microscope
...e. "Physicists have giant particle accelerators to isolate the fundamental elements of energy and matter. Now researchers in genetics and biology have an advanced tool to examine the very structure of the mouse, human and other genomes." The 4Pi microscope is manufactured by Leica Microsystems in Mannheim,...Single isolated mouse skin cell can generate into variety of epidermal tissues
...s is to see if these methods can now be adapted to isolate human hair stem cells for developing future treatm...study, the Fuchs' team of researchers were able to isolate these stem cells from normal mice, graft them on to the backs of hairless mice, and generate luxuri...Genuine stem cells found in skin might treat hair loss, wounds
...w methods devised by the team then allowed them to isolate those two cell types for independent examination of their behavior and molecular properties. While both cell types exhibited growth inhibition within their niche, the two underwent stem cell self-renewal in laboratory dishes, a quality that could pro...Skin stem cells give hairless mice hair
...nt aspect of this paper was that we found we could isolate and characterize these cells by taking advantage of the cell-surface markers that we had previously identified from molecular profiling experiments," said Fuchs. "We can now utilize similar methods to begin to compare mouse and human skin stem cells....MIT team explains yin-yang of ginseng
...sion. With the new results, "we can now rationally isolate the components to focus on a specific effect, such as promoting blood-vessel formation." In the United States, herbal medicines are currently regulated under the 1994 Dietary Supplement and Health Education Act, which does not require standardization...Researchers uncover secrets of immune system's munitions factory
...he current work, Chaudhuri developed techniques to isolate purified AID from B cells and test its activity on the target for somatic hypermutation. In this way, he found that the enzyme requires an unknown co-factor that was critical for AID function and that this co-factor specifically interacts with AID. ...Regular physical activity really does boost immune system in older men
...pet hemocyanin), a benign T cell-dependent protein isolate that has been used extensively with animals in the past, that also is safe for humans. The study, entitled "Influence of age and physical activity on the primary in vivo antibody and T cell-mediated responses in men," appears in the August 2004 issue...Researchers report new gene test for isolated cleft lip and palate
...he complexity. One productive inroad has been to isolate genes linked to "syndromic" cleft lip and palate, hoping some might also play a role in causing the isolated condition. Syndromic cleft lip and palate refers to babies born with clefts that are accompanied with other birth defects. There are over 1...Protective mechanism exploited by tumors may provide new cancer treatment
...nse. The MCG researchers were able to identify and isolate the IDO-expressing cells recruited by the tumor by using state-of-the-art cell-sorting equipment purchased for MCG by the Georgia Research Alliance. "Once we had them isolated, that allowed us to test them in vitro to see if they really were suppress...Oxygen sensing in worms may hold key to healthy blood pressure in humans
...t would," says Marletta. "However, we were able to isolate the enzyme's location in sensory neurons that are involved in communication with the outside world. From ongoing research with bacterially-related, cyclase-like sensor proteins, we got the idea that maybe the heme domain in GCY-35 was binding to oxyg...UNC research accelerates discovery of novel gene function
...DNA into a viral vector library, and it also helps isolate altered cells, ensuring that the changes in them a...changes in a particular phenotype. They can easily isolate and identify the gene causing the changes and place it into an animal model or bacteria for further ...Clemson researcher places hope on pushy photons
...the tissue environment on a small scale so we can isolate cell communication," Gao said. It is difficult to isolate messages that stimulate specific responses -- for example, the message that triggers the replaceme...Carnegie Mellon U. imaging study reveals sex-based differences that persist as mice enter adulthood
...ult). Koshibu used a software program to digitally isolate the whole brain and specific structures from the MRM data. These include the amygdala, hippocampus, striatum, and lateral and third ventricles, structures that have been widely studied in humans because of their implications in cognition and neuropsy...Carnegie Mellon U biologists identify critical player in yeast ribosome assembly
... accumulated within yeast cells, making it easy to isolate and study. Yeast engineered with mutations in genes for other proteins that direct ribosome assembly should yield even more intermediates for study, according to Woolford, whose research was supported by the National Institutes of Health and reported...