Tag: "itself" at biology news

Study by Israeli scientists provides insight on DNA code

...vents in which the spliceosome machinery assembles itself anew for each splicing job, the team's investigations of spliceosomes from live cells found splicing to take place in pre-formed machines. This fits in with what is known about the way cells optimize their workload. "It's much more efficient to have...

Newborns have ear preferences, too

...ons are sounds that are generated by the inner ear itself in the process of hearing. They can occur in an ear which is completely cut off from the rest of the brain, so long as the inner-ear hair cell system is intact. Sininger and Cone-Wesson found that healthy, non-hearing-impaired infants responded wit...

Wrapping a memory with an experience, capacity for recollection detected in non-human species

...ers. ROC analyses show that familiarity manifests itself as a continuous function reflecting the strength of a perceptual impression in memory. Recollection, by comparison, is expressed in an all-or-none fashion, triggered when a certain threshold of associative and contextual information has been achiev...

Smac-ing back at cancer cells

...d molecule is more active because the Smac protein itself is a combination of two identical proteins, althou...'s striking apoptosis-triggering activity revealed itself when the scientists introduced it into cultures of human glioblastoma cells. "We picked human gliobl...

Recent evolution at a single gene may have brought down heart disease risk in some human groups

...n its usual occurrence late in life, heart disease itself is considered to have been an unlikely driving force....

How do you mend a broken heart?

... investigate the ability of heart muscle to repair itself after being damaged by a heart attack, for example and to regain function. Prof. Rosenthal has previously shown that when a muscle is injured, stem cells can help the tissue rebuild. This team of researchers will build on her findings and use the c...

Single isolated mouse skin cell can generate into variety of epidermal tissues

...first time, that an individual stem cell can renew itself in the laboratory and then be used in grafts to produce skin, hair and oil glands. The study, published in the September 3 issue of the journal Cell, not only demonstrates for the first time the multipotent power of these stem cells, but also holds ...

Molecular staples shape a cancer killer

...y a short string of amino acids -- could insinuate itself into cancer cells to trigger their suicide. "Our goal was to modify the natural peptide sequence only enough to stabilize or reinforce its shape to improve its pharmacological properties," said Walensky. The researchers used the hydrocarbon stapling...

Stuck on you: Scientists lay bare secrets of bacterial attachment proteins

... called adhesins and invasins. The former attaches itself to the host cell and the latter assists the invasi...ssing protein sequence so that it could complement itself and fold correctly, demonstrating that the fibres assemble in an similar fashion to fimbrial protein...

Stopping skin cancer Stat3

...with this Stat3 functional inhibitor, tumor growth itself was impaired. This study provides the first evidence that Stat3 is required for the initiation of one form of skin cancer, and that it both mediates and maintains cellular growth through expansion of these initiated cells. These data also indicate...

JCI table of contents: 1 September, 2004

...with this Stat3 functional inhibitor, tumor growth itself was impaired. This study provides the first evide... immune responses to a variety of pathogens and is itself subject to autoimmune diseases. To investigate this paradox, Patrick Bertolino and colleagues used g...

Probing the surface of white blood cells to enhance immune system medicine

...y immune disorder that affects males and manifests itself through low platelets and recurrent bacterial infections. These conditions can eventually cause a fatal hemorrhage or infection in these patients. Higgs and his team found no differences in the length or density of microvilli on the lymphocytes, desp...

Integrative biology of exercise APS Intersociety meeting October 6-9, 2004 in Austin

...on of so many volunteered papers really speaks for itself and reflects the great interest generated by this conference," said Ronald L. Terjung, chair of the organizing committee of the meeting and professor in the Department of Biomedical Science at the University of Missouri-Columbia, College of Veterinar...

Images reveal how rotavirus - leading cause of diarrhea - enters cells

...e virus's surface proteins, called VP4. Rotavirus itself is a large, soccer ball-shaped, 20-sided particle with three layers. "The outside layer is like a landing apparatus and is stripped off in the course of entry," explains Dormitzer, who also is an assistant professor of Pediatrics at HMS and is affil...

Carnegie Mellon scientists reveal ways of studying, resolving PCB contamination in US rivers

...ent particles embedded in a plastic mesh, which is itself enclosed in geofabric. This thin "active" mat, which can be rolled out and placed within a conventional sand cap, could provide an important alternative to dredging, which is estimated to cost at least $500 million along the Hudson River alone. (See ...

Genetically-engineered 'marathon mouse' keeps on running

...sed number of fat-burning muscle fibers appears by itself to be protective against a high-fat diet," he said. "And that's important because it indicates that the presence of more mitochondria in the muscles of these animals probably results in more burning of fat and the release of some energy as heat." "T...

In gene regulation, small is beautiful

...e regulated, and a regulatory domain that attaches itself to the cell's machinery and activates or represses the gene. Recently, U-M assistant professor of chemistry Anna Mapp and coworkers designed small molecules that mimic in a general way the features of natural transcriptional activators. In this rese...

Virus known for its photo ops makes its movie screen debut

...it provided of the part of the virus that attached itself to E. coli's surface. "It was good to see the baseplate at such unprecedented resolution, but the infection process is not a still picture - it's a story," Rossmann said. "We knew we needed to see more than one scene in that story if we were ever to...

Heartless worms hold clues to cardiac arrhythmias, sudden death

...tigators have demonstrated that variations in HERG itself do not account for the majority of interindividual differences. Petersen and colleagues suspected that other proteins -- modulating factors -- are influencing HERG channel susceptibility to drug block. That's where the worm came in. "This paper is r...

Enzyme activation appears key in helping internal clock tell night from day

CHAMPAIGN, Ill. -- Feel like time is repeating itself and won't move on? It could be your internal clock is backpedaling because your PKG-II is out of whack. That scenario was played out at the University of Illinois at Urbana-Champaign in experiments at a molecular level deep within the brain of rats ...

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