Research shows oceans are becoming more acidic
... has been much debated, the direct impact of CO 2 itself has largely been neglected. However, they concluded, changes are clearly underway and their effects may be large and may seriously destabilize marine ecosystems. Their report signals the need for more research and identifies research priorities, in a...Italian research links diet with endometriosis risk
...the womb, develops outside the uterus and attaches itself to ligaments and organs in the abdominal cavity. This tissue responds to the menstrual cycle as though it were still inside the uterus. The repeated growth and disintegration of endometrial tissue in the abdomen can cause bleeding, pain, inflammation...Findings suggest need for new view of p53 cancer protein's interaction with DNA
...tein in its natural cellular environment assembles itself into tetramers symmetrical molecules made up of four copies of the p53 protein. Halazonetis hypothesizes that both Cep-1 and p53 exist primarily as tetramers under normal circumstances and that it is in that form that they bind their respective, but...UCSD biologists discover cell's defense mechanism against class of disease-causing bacterial toxins
... the innate animal immune system reacts to protect itself against a major bacterial virulence system," says Raffi V. Aroian, an associate professor of biology at UCSD who headed the team. "By learning how we can enhance and protect that defense mechanism in human cells, we can help protect people from many ...National Bioinformatics Resource Center to support infectious disease research
...rmatics Institute at Virginia Tech has established itself as a leading center for advanced research." Sobral will lead the project and VBI's Joao Setubal is co-principal investigator. Other Virginia Tech faculty members include Stephen Boyle from the Virginia-Maryland Regional College of Veterinary Medici...Confidentiality of genetic databases questioned by Stanford researchers
... found that's really not true because the DNA code itself is an identifier." To demonstrate this, the researchers looked at specific sites in DNA that commonly vary from person to person, accounting for many genetic differences. Each person has about 5 million such sites in their DNA. Using a statistical mo...Tracing a killer's path in Lou Gehrig's disease
...itochondria of spinal cord neurons, where it links itself to the mitochondrial membrane. Mitochondria are th...pinal cord neurons, mutant SOD1 specifically links itself to a key mitochondrial protein, called Bcl-2, that normally suppresses the apoptotic machinery of ce...Protein controls acid in cells by direct detection of volume changes, study finds
...he cell as it is moving, and is always rearranging itself to be at the cell's head. "While the cancer applications are very speculative, understanding this system can be very important for many aspects of cell biology," he said. The new study also compares NHE1 to another, very similar transporter called NH...Combination of gene therapy and gene silencing prevents neurodegenerative disease
...ortant finding was that RNA interference in and of itself does not appear to be toxic to normal brain cells. In the UI study, neither animal behavior nor brain structures were adversely affected by RNA interference gene therapy. Furthermore, the study revealed that specific properties of different gene ther...As humans alter land, infectious diseases follow
...otes, can trigger a chain of events that manifests itself in the emergence of new diseases. An example cited in the report is the emergence of nipah virus in Malaysia and Singapore in 1999 when El Nino-fueled fires are thought to have driven fruit bats from their forest habitat to farms where the virus was ...ORNL adds three R&D 100s to DOE lab-leading total
...e perchlorate, or ClO4, destroy it, and regenerate itself so it can be reused. Perchlorate, the primary ingredient of solid rocket propellant, is increasingly being discovered in soil and water. The chemical disrupts function of the human thyroid gland, which regulates metabolism in adults and physical de...How DNA repair machinery is a 'Two-Way Street'
...ed exonuclease I -- in the right direction to work itself along the strand, stripping out the segment containing the mismatch. "A surprising feature of the repair system that it can evaluate the placement of the strand signal to one side or the other of the mismatch and work from there," said Modrich. Accor...Design competition for new Antarctic Research Station
...rchitecture, technology and engineering that lends itself perfectly to an international design competition.' The competition begins with a call for Expressions of Interest from multi-disciplinary design teams. A shortlist will be invited to submit Concept Proposals and selected teams will then be commissi...Deserts and rainforests are equally productive during drought
...ecipitation becomes more variable, the variability itself will increase the sensitivity and vulnerability of the ecosystem with the same impact as reducing the precipitation. Other investigators included Travis Huxman of the University of Arizona who was co-author; Philip A. Fay of the Natural Resources R...RSV can increase the risk of asthma, UT Southwestern researchers find
...ld potentially prevent RSV-related asthma. That by itself would affect a vast number of patients and affect their quality of life as children and later as adults." Earlier studies have shown that the drug Palivizumab resulted in a 55 percent reduction in hospitalizations for RSV when given monthly during th...Earliest evidence of hereditary genetic disorder discovered by Hebrew University researchers
...imperfecta is a hereditary disorder that manifests itself in tooth enamel that is abnormal in structure, low in mineral content and hence subject to rapid wear and chipping. The Hebrew University researchers confirmed the clear presence of the disease in the fossil sample through x-ray and scanning electron...Purdue yeast makes ethanol from agricultural waste more effectively
...n as ethyl alcohol, ethanol can be used as fuel by itself or blended with gasoline. The Purdue yeast is used in combination with other technologies under development that first convert agricultural materials to xylose and glucose, said Purdue's Michael Ladisch, Distinguished Professor of Agricultural and Bi...Finding the hole in the defenses of cavity-creating microbes
...he bacterium rearranges its cell membranes to make itself impervious to the acid assault that it lets loose.... for some time that the microbe specially modifies itself once it starts producing acid in the mouth. The Quivey group has shown that the changes include shu...Biologists ID defense mechanism of leading fungal pathogen
...der to find the genes that Candida uses to protect itself against nitric oxide, or NO. Human immune cells give off NO to slow the growth of yeast colonies. The study, published in this month's issue of the journal Eukaryotic Cell, isolated one gene that appears to play a critical role in Candida's NO defens......opied to become double-stranded in order to insert itself into the human genome. The DNA appears to do this without incident, copying the mutations along with the original genetic information. Harris and others have observed that if VIF is not there to interfere, the two APOBEC proteins may mutate up to 25 ...