Washington University in St. Louis leads group studying aging process
...hington University Science Outreach program, which keeps K-12 teachers and students up to date in science and engineering trends. Undergraduate, graduate and post-doctoral researchers will get hands-on experiences with the "New Biology," which today is comprised of a good dose of mathematical, statistical...Genetically-engineered 'marathon mouse' keeps on running
... they have built a kind of metabolic "shield" that keeps them from gaining weight," said Evans. Also, when normal mice received the PPAR-delta-enhancing drug, they showed a virtually identical protection against weight gain, said Evans. The genetically altered mice also had lower levels of intramuscular t...New compound could give some types of cancer the one-two punch
...poptosis cell suicide in cancer cells because it keeps key structures called microtubules from working during cell division. Microtubules distribute chromosomes to new cells. OSU 111 also prevents tumor cells from forming new blood vessels. Scientists are looking for alternatives to established anti-canc......lved in overlapping feedback loops. The clock also keeps time dynamically, constantly shifting to stay in t...me's own transcription. This feedback loop is what keeps the body entrained to a 24-hour day. Since Bmal-1 is so crucial to keeping the body's clock entra...Leukemia stem cells identified by Stanford researchers
...tein is commonly found in embryonic cells where it keeps them in a dividing state. "What's novel is that you have this gene turned on in a mature cell," Jamieson said. The protein was particularly abundant in people whose cancers were resistant to the chemotherapy drug Gleevec. Beta-catenin is part of a pa...Scientist who discovered Sly syndrome finds new research path to explore for treating the disease
...tion of how does the cell decide which proteins it keeps inside and which it translocates to its surface. The whole question had been posed as a problem of inventing a blood-brain barrier delivery system," said Banks, who also is a staff physician at Veterans Affairs Medical Center in St. Louis. "Now we ha...Commercialization deal boosts hope for new sickle-cell drug
... and water exit the cell. Blockade of this channel keeps the cells hydrated, resulting in much less sickling. The CHB researchers also discovered that clotrimazole has metabolites (breakdown products) that can reduce sickling without the liver toxicity and other side effects of the mother drug. The...Spring through fall, cities are greener longer than neighboring rural regions
...ows plants to bask in a hot-house environment that keeps them greener longer. Recent NASA-sponsored research from a team of geographers in Boston University's Center for Remote Sensing shows that the growing season for vegetation in about 70 urban areas in North America is, on average, 15 days longer than...Save the rainforest - eat a tree
...unch on trees. Such seemingly destructive behavior keeps dominant tree species under control but allows other trees to thrive. "The battle between plants and insects increases the number of habitats in the rainforest," thus increasing the diversity of trees living there, says biology doctoral student ...K-State professor combines love of teaching, research to examine eye development
...ssor of biology at Kansas State University, always keeps paper and writing utensils all around his house, office, car, etc. These ideas have proven to be quite beneficial to eye research, as Conrad has obtained seven, five-year research grants over a 33-year period. Conrad enjoys doing both research and t...Protein key to trafficking in nerve terminals
...erly, or occurs too late. As a result, the vesicle keeps growing and subsequently becomes loaded with too much neurotransmitter. Bellen and his colleagues believe that Dap160 stabilizes the complex of molecules involved in the retrieval and formation of vesicles, allowing for neurotransmitters to be relea......nts chlorine, bromine, iodine or fluorine. Gribble keeps a record of newly discovered natural organohalogen...g organohalogens. He catalogues the references and keeps track of them all. Gribble emphasizes that many of these natural organohalogens have potent antican...Mouse brain stem cells capable of converting into blood vessel cells
...nding doesn't fully answer this vital question, it keeps open the possibility that adult stem cells from different organs one day may be harnessed to help prevent and treat neurological disorders." In their experiments, Gage and his colleagues grew mouse brain stem cells, which form neurons and glial cells...... resting cells because it is bound to RhoGDI. This keeps the Rac in the cytosol and away from the cellular membrane, where Rac's molecular targets reside. When the cell receives activation signals, the Rac GTPases will dissociate from the RhoGDI in the cytosol and move to the ruffles at the edges of the ce...Bacteria spill their guts to aid researchers in quest for new antibiotics
New findings about a protein that keeps cells alive by opening and closing pores within a cell's membrane may open the door to the development of new antibiotics. Researchers at UT Southwestern Medical Center at Dallas are studying a protein, called MscL, found in the membrane of the singl...Scientists discover genetic marker responsible for two-fold increase in risk of rheumatoid arthritis
...ich in turn interrupts the communication lines and keeps immune cells from becoming overactive. In cases where the SNP is present in one or both copies of an individual's genes for this enzyme, the team found that the negative regulation by this enzyme appears to be inefficient, so that T cells and other i...'Mighty mouse' gene works the same way in people
... myostatin gene, proving that its protein normally keeps muscle development in check in people. People with muscle-wasting conditions such as muscular dystrophy, and others just wanting to "bulk up," have eagerly followed work on myostatin, hoping for a way to counteract the protein's effects in order to ...Next best thing: wood chip bedding for cattle
...ood chip bedding requires less frequent additions, keeps animals cleaner, and can be cheaper in drought years when straw is scarce. However, the effect of different bedding materials on greenhouse gas emissions during composting of manure had not been previously studied. Greenhouse gases are emitte...Harmless virus helps slow HIV by boosting immune proteins
...ite favored by HIV-a receptor called CCR5-and thus keeps the AIDS virus from binding to white blood cells and gaining a foothold in the body. Drugs are under development that mimic the effect of these chemokines. However, Stapleton believes GBV-C itself should be seen as a potential HIV treatment because ...Altered protein involved in a novel link to Alzheimer's disease
...ays Dr. Tsai. Unlike its shorter-lived parent, p25 keeps accumulating in the brain. It causes its most severe damage indirectly, however, by the way it alters the behavior of an enzyme in the brain called Cdk5. When Cdk5 pairs with the original p35 protein, it assures that the brain's neurons remain health...