Tag: "kidneys" at biology news

New 'clock gene' uncovered

...ssues of the body. The liver, the heart, and the kidneys each have their own distinct clocks. The liver, for instance, expresses a number of enzymes that remove toxic substances from the bloodstream during the day, which corresponds with the prime time for food (and toxic compound) intake. Coordinating t...

U-M scientists find common virus in human prostate tissue

... Most of the time, the virus lurks quietly in the kidneys without causing problems. But in people with a depressed immune system especially those who have just received a kidney transplant the virus can cause serious kidney and bladder disease. Now, new research by scientists at the University of Mi...

Iron can have negative side effects on people with kidney disease

...s, its potential toxicity might be even greater in kidneys affected by disease. The journal Kidney International, published by Blackwell on behalf of the International Society of Nephrology, just released findings from an experimental study revealing that intravenous iron therapy administered to patients wit...

Newly grown kidneys can sustain life in rats

...bryonic tissue transplants can be used to grow new kidneys inside rats. In their latest study, though, they put the new kidneys to an unprecedented and critical test, removing the rat's original kidneys and placing the new kidne...

Lupus Research Institute awards $3 million in novel research grants to further new science in lupus

...rchers will identify inflammatory molecules in the kidneys and urine that are associated with remission and relapse, and will use this information to study the urine of patients entering a clinical trial of a new therapeutic regimen for lupus nephritis. Umesh S. Deshmukh, PhD, University of Virginia, Char...

Once a renin cell, always a renin cell

.../or low blood pressure in the blood vessels of the kidneys and it plays a major role in regulating blood pressure generally in the body. Adult mammals can increase circulating renin, when necessary, by increasing the number of renin-synthesizing cells. Dr. R. Ariel Gomez from the University of Virginia and c...

Inflammation, hypertension are focus of major new MCG research program

...the problems that occur in the microvasculature of kidneys in hypertension. "We have been interested in the hypertension angle because we know blood vessels in the kidney don't function correctly; they also don't function correctly in diabetes. These two diseases are major players for kidney damage and it'...

Salty scans

... and her lab team have found a way to see into the kidneys using magnetic resonance imaging (MRI) that scans ... layers inward. Next, they continued their work on kidneys with altered function to see how effective a diagnostic tool the sodium imaging is. When the kidneys...

Delirium high in ICU patients, leads to death, morbidity

...ent and they have been studying how to prevent the kidneys and lungs from shutting down during a critical illness and what treatment is appropriate. "But since we didn't recognize that brain failure was a problem, those studies haven't been done yet for the brain. It is ironic because the brain is arguably ...

JCI table of contents, 15 March 2004

...pected, PKHD1 gene expression was decreased in the kidneys of transgenic mice. Examination of renal histology revealed renal cysts in these mice. Finding a commonality in the mechanism of these diseases may enable shared treatment strategies for renal cyst diseases. TITLE: Mutation of hepatocyte nuclear fact...

Watching genes in action

...rth defects and creating artificial organs such as kidneys for people whose own organs have failed. A University of Utah study describing development of the new method was published in the March 2004 issue of the journal Developmental Dynamics. Mauch an associate professor of pediatrics and adjunct ...

Embryonic pig cell transplants halt rat diabetes

...f kidney primordia from embryonic pigs to grow new kidneys inside recipients as a treatment for end-stage kidney failure. ...

Immune system's attack dogs kept on genetic leash

..., with inflammation in the salivary glands, lungs, kidneys and several other organs. The protein made from the gene already was known to be a transcription factor -- a protein that promotes or suppresses the creation of proteins made from other genes. Peng found that lack of the Foxj1 protein increased acti...

Out-of-balance ecosystems play role in demise of amphibian populations

... of frogs in Minnesota. These parasites attack the kidneys rather than the limb-bud areas of tadpoles. In the... , they reported that when echinostomes attack the kidneys in early development, about one week after hatching, infections lead to the blockage of kidney funct...

Kidney injury's harmful effects on bones blocked in mice

...dism and ABD occur both in patients who lose their kidneys to disease and in those who suffer a sufficiently damaging kidney injury. Studies of both conditions in human patients and animal models recently have uncovered a complex network of links between the skeleton and the kidney. "We're learning that horm...

Other highlights in the December 17 issue of JNCI

...cin may be more effective and less damaging to the kidneys than the traditional three daily doses in children with fever and neutropenia (reduced white blood cell count) who are undergoing stem cell transplantation, according to a study of 60 children randomly assigned to the two regimens. Lillian Sung, M.D....

JAK2 enzyme helps protect brain cells, wreaks havoc on blood vessels

...r. Marrero says. In the face of high glucose, the kidneys are an easy target for JAK2's detrimental effects, prompting glomeruli mesangial cells to grow and proliferate, thereby clogging the kidneys' intricate filtering mechanisms, according to his work published in the December 2002 issue of Diabetes. "Tha...

Sugar coupled to protein causes kidneys to save water

...transport of water channels to the cell surface of kidneys have been identified by a Dutch researcher. The wa...ed waste substances from the blood. Each day human kidneys produced about 180 litres of this so-called pro-urine. The excretion of all of this fluid would rapi...

Obesity, kidney genetics, erectile dysfunction among highlighted research at APS Meeting

...003 (Bethesda, MD) Our heart, blood pressure and kidneys are essential for life, and the healthy interplay ...structions to the heart, the blood vessels and the kidneys about what to do. Our individual genetic code, the individual proteins that create the genes, and th...

Researchers involved in renal and cardiovascular function gather for fall conference

...003 (Bethesda, MD) Our heart, blood pressure and kidneys are essential for life, and the healthy interplay ...structions to the heart, the blood vessels and the kidneys about what to do. Our individual genetic code, the individual proteins that create the genes, and th...

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