Disconnecting molecular handbrakes has drastic consequences
...stem withouta brake and allowing it to produce all kinds of noxious inflammatorysubstances." In a second article, Ihle and his colleagues demonstrated that knocking outthe related gene, SOCS3 , triggered an enormous overproduction of redblood cells, which killed developing embryos. The researchers' knock...Mayo Clinic study implicates fungus as cause of chronic sinusitis
...ts' mucus. They identified a total of 40 different kinds offungi in these patients, with an average of 2.7 kinds per patient. In a subset of 101 patients who had surgery to remove nasal polyps, theresearchers fou...Diet and cancer prevention: a sampler of story ideas for '5-a-Day for Better Health Week'
...ion programshave been successful so far, and these kinds of programs cannot be deliveredthrough mass media." Dr. Kristal, who studies the link between diet and prostate cancer prevention,is also a trained chef, so he can talk about food preparation that is sensibleand healthy, and creative ways to incorpor...UCSC researchers obtain first detailed images of a complete ribosome
...antibiotic binding sites, and that may lead to new kinds of drugs," he said....Yale scientists find evidence healthy animals detect and avoid sick animals
...anged drastically since itwas discovered that many kinds of prey animals can change their behavior andeven their body shape when they smell nearby predators," Skelly said."Responding to disease risk may be quite similar from an animal's perspective.In both cases animals appear to be able to use behavior to...Researchers say hormones are key to evolution of insect metamorphosis
...erent types of development is timing, when certain kinds ofproteins are made, how long they're present, and so on," Truman said. Hebelieves metamorphosis will provide a valuable model for researchers tounderstand the molecular basis for how shifts in the timing of proteinproduction can lead to the creation...Researchers discover location of a testicular cancer gene
...w and powerful way to simplifythe analysis of many kinds of highly complex traits." For Nadeau and colleagues, the search is now to discover the identity ofthis important new testicular cancer susceptibility gene. This new strain withits high frequency of testicular cancer is also the long-sought m......ntually, the approach should beapplicable to other kinds of cancer, notably breast, prostate and childhoodt...tage colon tumors, a type of ovariancancer and two kinds of lung cancer. The researchers expect to analyze more than 1,000 different proteins from eachkind ...NIH grantee Günter Blobel wins Nobel Prize for protein signaling discovery
... of proteins in the cell, and even on the way some kinds ofdrugs may be introduced into cells." Dr. Blobel's work has focused on the mechanisms by which proteins are moved, ortranslocated, across cellular membranes. In the early 1970s, he formulated thehypothesis that in order for these proteins to be tra...New molecular clues to herpes control
... specifically target viral proteins that affectthe kinds of cell signal transduction pathways and transcription factors we arestudying here. But these would have to be targeted to the viral part of theequation not the normal cellular part, as these signaling activities occur inevery cell," Bachenheimer sai...Just how serious a problem is alcoholism?
... alcohol-dependent individualswho seek out certain kinds of treatment often have similar characteristics. Theresearchers looked at three groups: those who had experienced at least onein-patient treatment, those who had received only out-patient treatment orattended AA meetings, and those who had experien......very basic science, but it keeps showing up in all kinds ofareas and is clearly a broadly occurring phenomenon," Barisas said. "Our hope isthat we can find ways to turn this knowledge to practical uses."...Discovery of oldest dinosaur bones reported in Science
...he Malagasy finding isunique in containing various kinds of animals -- such as certain non-dinosaurianrepti...e co-occurrence ofdinosaurs and these more ancient kinds of animals -- as well as thenon-occurrence of younger groups -- argues for the antiquity of the dino...Scientists document most recent date for Neandertals
...stone andbone tools.The Vindija site produced both kinds of tools, including a beveled bone probablyused as the tip of a spear. "The big question is: 'Why do we have a combination oftools?' " Smith said. "It's possible Neandertals developed all these tools or got the bone toolsthrough trade with moderns," ......hiralchemicals. "It appears that different kinds of environmental changes turn ondifferent genetically related groups of microorganisms," said Dr. Eric Wommack,who carried out the genetic experiments in the study. This may explain whyenvironmental changes affect which mirror-image molecules persist...Shedding light on the origin of primate color vision
... genes from tissue samples taken from 20 different kinds of prosimians, mostly lemurs. They found the polymorphism in two diurnal species (active during the day) and in one nocturnal species. Because color vision is useful only in daylight, Li wasnt surprised to find the polymorphism in the diurnal pros...Science and Amersham Pharmacia Biotech award Young Scientist Prize
...ed to look at genes in human disease, such as what kinds of genes might serve as disease markers, which gen...w a few cases of gene expression relate to certain kinds of cancer, but lack an overall picture of gene activity in cancer cells. For instance, Velculescu sa...Health of normal synapses seen to depend on neurotrophin signaling
...ngmight someday be used to protect against certain kinds of synaptic failure. "In aging animals and in aging humans, thesynapse we studied -- the neuromuscular junction -- falls apart over time in much the same way it did in our neurotrophinexperiments," says Rita J. Balice-Gordon, Ph.D., an assistant pro...New Cosumnes River research partnership announced
... and its surrounding floodplains support dozens of kinds of native fish, including the endangered chinook salmon and the Sacramento splittail, which is a candidate for the federal endangered species list. One of the most interesting experiments already under way in the watershed was begun in 1995, when Na......on, which will include about one-eighth of all the kinds of plants in the world. Flora China is being organized so that it will also be available electronically and interactively. "Exploring the basic rules that govern the functioning and growth of living organisms, in a field that has exploded over the ...