Cancer drug resistance research leads to possible therapeutic target for Alzheimer's disease
...ssue. The research was conducted in the Fox Chase laboratory of Kenneth D. Tew, Ph.D., D.Sc. Tew's research has...anges in gene expression with little material, his laboratory developed Amplified Differential Gene Expression (ADGE) technology and ADGE microarray ("gene chip" ...Without words, bullfrogs communicate through stutters in their croaks
...nd Research Assistantship (UTRA) program. Simmons' laboratory is supported by a research grant from the National Institutes of Health....Researchers discover protein that dissolves amyloid fibers
...plexed scientists with their robust structures. In laboratory experiments, they are able to withstand extreme heat and cold and powerful detergents that cripple most other proteins. The fibers are in fact so tough that researchers now are exploring ways that they can be used in nanoscale industrial applications...MBL researcher and science teacher visit Siberia to study climate, excite children about science
...nded in 1888, the MBL is the oldest private marine laboratory in the Western Hemisphere.......financial stake in Nanobac. "We are an independent laboratory and we have provided new evidence," Miller says. The paper went through seven cycles of revision before it was accepted by the American Journal of Physiology: Heart and Circulatory Physiology last week. "The review process, as painful as it was, for...Tigecycline - antibiotic evaluated in surveillance trial
...his study will enable us to document with in vitro laboratory data the activity of this new antibiotic against bacterial pathogens, including those exhibiting multiple antibiotic resistance," said Daryl Hoban, Ph.D., Director of Clinical and Laboratory Services. About T.E.S.T. T.E.S.T. investigators will col...NIH awards $20.7 million to make smallpox vaccine safer
...tis in the past. The researchers will conduct both laboratory and clinical studies to understand why atopic dermatitis patients are susceptible to eczema vaccinatum, to find biomarkers that can definitively identify atopic dermatitis patients in general and those who are especially susceptible to eczema vaccina...Gene expression profiling may predict head, neck cancer recurrence
... assistant professor of genetics and pathology and laboratory medicine at the University of North Carolina at Chapel Hill School of Medicine, led the study. Writing in the May 18 issue of the journal Cancer Cell, Perou, also a member of the UNC Lineberger Comprehensive Cancer Center, and colleagues from UNC an...Pancreatic cancer blood test & gene studies show promise
...ancreatic cancer," says Diane Simeone, M.D., whose laboratory team made the cell signaling discovery and who co-leads the U-M effort to translate basic genetic research into clinically useful tests. The newly announced findings all stem from research led by Simeone and Craig Logsdon, Ph.D. One year ago, they pu...Other highlights in the May 19 JNCI
...Designing a sequential series of experiments, both laboratory and clinical, that lead intentionally to proof-of-concept adjuvant trials is all too rare. But, as Pegram et al. remind us, it is not impossible," he writes. Contact: Kim Irwin, Media Relations, Women's Cancer Program Area, UCLA's Jonsson Cancer Cent......nclude teaching experiences, and a mobile teaching laboratory to bring science to disadvantaged and minority stu...mentor middle- and high-school students, providing laboratory experiences and writing workshops. The colleges also will offer summer workshops for Philadelphia ar...Drug combo effective in advanced breast cancer
... of studies at UCLA's Jonsson Cancer Center taking laboratory science to the patient bedside found that combinin...f the studies, the first done on cell lines in the laboratory and the second translated into more than 120 patients in two Phase II clinical trials, appear Tuesda...NPS Pharma and VIMAC Ventures locate at MaRS, a major new research and enterprise center in Toronto
...3 million square feet, which will be available for laboratory research, business offices, meetings and conferences. The MaRS Discovery District is a federally incorporated, not-for-profit corporation, founded by leaders from Canada's academic, business, and scientific communities....Mouse study yields clue to why liver is less prone to rejection, say Pitt researchers
... Dr. de Creus, a research associate working in the laboratory of Angus Thomson, Ph.D., D.Sc., professor of surgery and immunology at the Thomas E. Starzl Transplantation Institute and University of Pittsburgh School of Medicine. "In humans, perhaps it would be possible to manipulate dendritic cells of the dono...New screening method turns up potential compound for treating anthrax
... of a deadly toxin called anthrax lethal factor in laboratory tests. Nature Biotechnology will publish the f... that a mass spectrometry method used in Mrksich's laboratory could be beneficially applied to drug screening. Min's work is supported by the University's Burroug...Scientists discover secret of dolphin speed
...ow it down. To test their simulation, they built a laboratory experiment which mimics dolphin skin using a 'wavy' plate covered in tiny pieces of film that gradually peel off as water moves over the surface. Professor Hagiwara said: "It's really difficult to measure flow near swimming dolphins, so we designed a...Tips from the Journals of the American Society for Microbiology
...ugs or an effective vaccine for SARS virus. Rapid laboratory confirmation of SARS-CoV infection is therefore important for managing patient care and for preventing nosocomial transmission," say the researchers. In the study, throat and nasal samples were collected from hospitalized patients in Vietnam. Resea...From algae, weeds and people: new genetic clues to complex obesity syndrome
..., and then compared those matches to a weed -- the laboratory plant Arabidopsis. The alga and humans both have cilia, but the weed doesn't, so the researchers could eliminate genes and proteins that aren't involved in cilia, says Dutcher. The alga and humans shared 4,348 "fairly good" matches. Subtracting thos...Chemical reaction in birds provides sense of direction during migratory flights
...-week period in 2003 in Frankfurt, Germany, in the laboratory of Wolfgang and Roswitha Wiltschko, co-authors of the paper, who developed the behavioral experimental setup used in the study for testing magnetic orientation in birds. During migratory unrest, the birds could move in their cages. Each cage was funn...Oak Ridge National Laboratory to develop DOE leadership-class computing capability for science
...ation. The department determined that a national laboratory was the logical place for a national computational user facility for capability limited science, because at such a venue the DOE Office of Science can ensure world-class operations, maintenance, security and equal access to all prospective users on a...