Creation of the UK Clinical Research Collaboration will boost clinical trials in UK
...speed up the development of new medicines from the laboratory to the patient by expanding the number and range of clinical trials. "This will be a further major boost to the clinical research infrastructure in this country, making it even more competitive internationally," said Dr. Trevor Jones, Director Genera...UNC scientists discover molecular pathway leading to nerve growth and regeneration
...nal Cord Research Foundation who works in Snider's laboratory and is lead author of the study. In addition, the findings may be important to understanding how the brain is wired, said Snider. "We think the findings may be relevant to axon growth in the brain." In the study, Zhou took a novel approach to identif...Infusion of two peptides acts to accelerate appetite satisfaction
...y restriction; and normal physical examination and laboratory screening results. The study employed a randomized, placebo-controlled, double-blind, four-way crossover design in which each subject underwent four tests with the infusion of: saline, CCK-33, GLP-1, or CCK-33 plus GLP-1. Test trials were separated...Hopkins to found first center for comprehensive study of epigenetics
... status, the center will be bigger than Feinberg's laboratory alone. Among the key players are 15 other researchers from Hopkins and elsewhere whose work and collaborations will be critical to the center's success. "As we studied epigenetics in cancer, it became clear that we needed to 'genomicize' epigenetics...Noah's modern ark: The role of ART in conserving endangered species
...scientists who study ART in humans and domestic or laboratory animals, we face different problems and it is clear that the high tech components of the reproductive sciences are not a quick fix for enhanced reproduction in endangered species. "First, we are working with species that are often dangerous, if not...Natural selection at work in genetic variation to taste
... Fox accidentally let loose a quantity of PTC in a laboratory and noticed that while some people could taste it, others could not. After that, it was long hypothesized that alleles were responsible for the ability to taste PTC, according to Wooding. The PTC gene is only one of 24 bitter taste genes. Wooding and...A fly's taste experience is much like our own
...uoren Wang, graduate student Aakanksha Singhvi and laboratory manager Priscilla Kong - all with UC Berkeley's Helen Wills Neuroscience Center and the Department of Molecular and Cell Biology - reported their findings in the June 24 issue of the journal Cell. Scott said that the taste system of flies is much sim...APS awards more than $200,000 to middle and high school science teachers
...in 11 states. Twenty-two APS members working in a laboratory setting volunteer to host and mentor winning teach... paired with an APS member and becomes part of the laboratory team. The 2004 Frontiers in Physiology Research Teachers are: Charles Allen Custer High School, M...Mutant mice lead to memory insights
...ues studied a mutant mouse -- developed in another laboratory -- in which one of the two copies of the gene for CBP had been knocked out. Such "haploinsufficiency" is thought to be a good animal model for Rubinstein-Taybi syndrome, because it mimics many of the symptoms of the disease. In their studies, the re...'Mighty mouse' gene works the same way in people
...Ph.D., who tested the genetic mutation's effect in laboratory studies. "If the message had been used to make a protein, it would be much shorter than it should be. But we think the process doesn't even get that far; instead the cells just destroy the message." Co-authors from Wyeth Research, Cambridge, Mass., a...Clinical judgement still counts strongly alongside genetic testing
...mer said: "While there are an increasing number of laboratory examinations that can be made to investigate possible dysmorphic conditions - including DNA and chromosome testing - it is not the case that these are supplanting clinical expertise. Laboratory tests do not simply outweigh clinical evidence." ...New computational tools to aid in protein research
...ristopher Langmead, a doctoral student in Donald's laboratory who is now an assistant professor of computer science at Carnegie Mellon University. Langmead's algorithm introduced new techniques for assigning NMR measurements to specific molecular bonds. Most NMR experiments measure a protein, reporting distance...New York City study shows newborns more susceptible to pollution than their mothers
...ly notable since evidence from previous studies of laboratory rodents suggests that the fetus is more susceptible to the carcinogenic effects of the same pollutants than the adult. The study was designed to measure the effects of prenatal and maternal exposure to combustion-related pollutants, known as polycycl...Protein believed to control formation of memory identified by Scripps & UCSD scientists
...in Memories Scientists have long known that when laboratory animals are treated with a class of drugs known as protein synthesis inhibitors, which stops the production of proteins in the animals' brains, these animals lose their long-term memory. This observation has led scientists to predict that the formati...Device that rapidly detects nerve agents named one of 'greatest army inventions' for 2003
...ntions Program were submitted from across the Army laboratory community and evaluated by soldier teams from the U.S. Army Training and Doctrine Command and active U.S. Army divisions. The entries were judged based on their impact on Army capabilities, potential benefit outside the Army and their inventiveness. ...Antioxidants during pregnancy may help prevent birth defects tied to alcohol
...is technique, early mouse embryos are grown in the laboratory and exposed to various levels of ethanol and antioxidants. Embryos are then monitored for evidence of cell death and abnormal development."Using this method, we also showed that SOD can diminish ethanol-induced cell death and subsequent malformations...Lupus Research Institute awards $3 million in novel research grants to further new science in lupus
...te development and progression of the disease. The laboratory has recently made the novel discovery that the molecule CD5, expressed on all T-cells, is a key regulator of survival. The researchers propose that blocking the signal of CD5 will promote cell death of autoreactive T-cells, a potential target for th...Study finds first evidence COX-2 enzymes can regulate DNA damage
...ot in surrounding healthy tissues. The Vanderbilt laboratory then developed a cellular model that introduced the COX-2 enzyme into cells to study the biochemical changes that occurred. In a spirit of scientific collegiality, the Vanderbilt group supplied Dr. Blair's lab their cellular model so that the Univers...TIGR president discusses significance of finding anthrax toxin
...These data further highlight the challenges in the laboratory and clinical differential diagnosis and response to naturally occurring pathogens that may resemble known bioterror agents," says Dr. Fraser. She says the TIGR/CDC study also shows how genomics can rapidly assist public health experts in responding n...Scientists receive awards, give lectures at the ASBMB/IUBMB meeting
...n research. Among other achievements, Dr. Davis's laboratory was instrumental in the development of phage lambda vectors, which are now the most common method for the primary closing of cDNA molecules using E. coli. His current focus is on whole genome analysis, and his contributions have led to the completio...