How DNA copying enzyme 'stops the presses' for repair synthesizing enzyme
...tself, triggering the mismatch repair machinery to launch into action, before replication can continue. This stalling is thought to occur because the polymerase-DNA structure is distorted by the mismatched bases, causing it to shut down. The problem, said Beese, who is an associate professor of biochemistry...Fox Chase Cancer Center research reveals how COX-2 causes ovarian cancer
...ells. In fact, the National Cancer Institute will launch a human clinical trial of COX-2 inhibitors. Mary B. Daly, M.D., Ph.D., director of Fox Chase's Cancer Control Program, is heading the multi-center trial, which will include Fox Chase as one of its sites. Fox Chase has one of four Specialized Progra...Media advisory: Sea of Cortez expedition to launch March 26
3/24/04Media are invited to attend the launch of the Sea of CortezExpedition and Education Project, which will depart from Municipal Wharf II in Monterey, Calif., at 10 a.m. Friday, March 26. Led by Stanford University biologist William Gilly, the two-month expedition will retrace a 1940 voyage ...Nerac rebuilds TOC Journal Watch service with new search engine
...ation services company, is pleased to announce the launch of a sophisticated online search engine for TOC Journal Watch. Clients can quickly search Nerac's database of 21,000+ publications to locate their favorite journals. Delivering the table of contents for new journal issues, TOC Journal Watch provides ...Astrazeneca announces EU marketing approval for Faslodex(TM)
...rom the University of Nottingham, UK, welcomed the launch of 'Faslodex' and commented on the benefit that the new drug brings: "The arrival of this new type of treatment is particularly exciting as it brings with it new choices for postmenopausal women with the advanced stages of this devastating disease."...Bioprocesses upstage traditional chemical processes
...down the adoption of bioprocesses. However, if the launch of blockbuster biopharmaceutical drugs for hepatitis, cancer, diabetes, and hemophilia, and the subsequent revenue surge for pharmaceutical companies in 2003, is any indication, more industries are likely to step up the deployment of bioprocesses. "T...VaxGen reports Phase I clinical trial results of anthrax vaccine candidate
...ional Institutes of Health (NIH). VaxGen plans to launch two Phase II trials of rPA102 this year, supported by separate NIAID funding, under contract N01-A1-30053. The first Phase II trial, scheduled to begin this month, is designed to determine the optimal concentrations of aluminum adjuvant and recombin...Envisat concludes a busy second year in orbit
... orbit 36,000 km above the Congo Basin. During its launch in July 2001 Artemis was placed in the wrong orbit, and mission controllers had to spend the next 18 months nursing the spacecraft up to its intended position. Envisat had always been designed to work in conjunction with Artemis. Without it the amou...New Web site for biogeoscience community announced
...lving scientific discipline. The Web site, due to launch in late spring of 2004, will be a focal point for information and discussion, as well as a resource clearinghouse. Content will include articles addressing growth and changes in the field, reports on leading research, and information on upcoming meet...ESA prepares mission to search for life on Mars
...t day," he added. ExoMars, which is scheduled for launch in 2009, includes an orbiter and a descent module that will land a large (200 kg), high-mobility rover on the surface of Mars. After delivery of the lander/rover, the ExoMars orbiter will operate as a data relay satellite between the Earth and the ve...New hereditary cancer mutation found -- arrived with a German immigrant almost three centuries ago
...s. The nine families then helped the investigators launch a major historical and genealogical study to trace their ancestry. This evidence allowed the researchers to conclude that the mutation was in either the husband or wife of a couple that had immigrated from Germany and settled in Pennsylvania in 172...ESA to select new Earth Explorer missions
...development in 1999, the first of which is due for launch at the end of this year. Over the last two years t...te Ocean Circulation Explorer (GOCE) scheduled for launch in 2006, which will measure high-accuracy gravity gradients and provide global models of the Earth's...A joint effort against the Oriental boil
...l scientific questions, Solbach would also like to launch a health policy initiative focused on preventing the disease. However, the professor from Lbeck concedes that other priorities exist in the region that is plagued by terrorist attacks (e.g., gunshot wounds are a bigger problem than leishmaniasis). S...New Georgia Tech Biosciences Center assists life-science startup companies
... facility and has provided more than $5 million to launch the new incubator. "Yet the benefits of this integrated model far outweigh any complications." The ATDC Biosciences Center is an important "first step" in advancing Georgia's bioscience prowess, Shows adds: "Although bioscience is growing rapidly, i...Successful progress launch paves the way for further scientific utilisation of the ISS by Europe
...TV retroreflectors, installed on Zvezda before its launch in 1998, will be brought back to Earth for materia...s in the manned Soyuz TMA-4. This is scheduled for launch from Baikonur as mission 8S on 19 April. Kuipers is currently training for the mission at Star City ...Gene may be key to evolution of larger human brain
... Deaconess Medical Center is what prompted Lahn to launch an evolutionary study of the gene. Lahn and his colleagues compared the sequence of the human ASPM gene to that from six other primate species shown genetically to represent key positions in the evolutionary hierarchy leading to Homo sapiens . Tho...Genetic master switch sends bacteria toward 'seafood dinner'
...very about how and when these microscopic soldiers launch their search-and-devour missions. Writing in the Online Early Edition of "Proceedings of the National Academy of Sciences" for the week of Dec. 29, 2003, Xibing Li and Saul Roseman reported that they had found a genetic master switch that reacts t...Armies of fighting fungi protect chocolate trees
...Arnold, the researchers' findings have led them to launch field trials in Panama, under co-author Herre, in which spores of local endophytes are being grown and sprayed on cacao plants, in an effort to reduce fungal infections. Such production of endophyte spores can be done inexpensively and easily by loca...Separation day arrives for Mars Express and Beagle 2
...rd, UK. The SUEM has two elements: the first, the launch clamp mechanism, will provide a secure mounting sy...ed during ground handling and lift-off. During the launch phase, three matched cup and cones transfer the launch loads from the probe to the orbiter. Each cup...Science's breakthrough of the year: Illumination of the dark, expanding universe
...ht gamma ray burst. NASA's Swift satellite set for launch in mid-2004 should catch gamma ray bursts at five times the rate of any previous mission. Spontaneous Sperm and Egg Cells: The surprising discovery that mouse embryonic stem cells can develop into both sperm and eggs may help s...