Are CDC's 1997 Recommendations For Targeted Lead Screening Of Children Justified?
...f Medicine argue that CDC's recentrevision of its lead screening recommendations for children which calls...ic approach." Even modestly elevated blood lead levels have subtle yet serious effectsthat can result in irreversible neurocognitive deficits. Resea...Researchers Discover New Genetic Risk For Alzheimer's Disease
...associateprofessor of genetics in psychiatry and a lead author of the study. Goate's team at Washington University collaborated with Spanishresearchers, led by Fernando Valdivieso, Ph.D., professor and chair of molecularbiology at the University of Madrid. The two groups studied individuals with...Peutz-Jeghers Disease Gene Identified: Enzyme Loss Causes Polyps And Cancer
...the Peutz-Jeghers syndrome. All these mutations lead to the synthesis of a truncated and inactive protein. The disease manifestations are triggered by the spontaneous loss of the second and only functional copy of this gene in somatic cells. Simultaneously and independently, a second resear......r typesof bacteria. The discovery could ultimately lead to the development ofgenetically-engineered crops ...m tomato, lettuce and rice,"said Carol Ishimaru, a lead researcher on the project and associate professor ofbioagricultural sciences and pest management at ...Genetics May Explain Why African Americans More At Risk For Strokes Caused By Bleeding In The Brain
...t onlylead to worse outcomes, but it also may also lead to an earlier onset," saysAlberts. Co-researchers include S.E. Moore, B.A.; K.L Hoffman, R.N; D.M. Delong,Ph.D.; C. Graffagnino, M.D.; C. Granger, M.D. and A.M. Saunders, Ph.D. of DukeUniversity Medical Center, Durham, N.C....Doublecortin : A Novel Gene Involved In Cortical Development
...l established thatdefective neuronal migration can lead to severe cortical malformations, but thefactors involved in this phenomenon are poorly understood. An interestingcandidate is the Doublecortin gene, which has just been identified by Vincentdes Portes and coworkers, who are part of the team headed b...Fruit Flies May Shed Light On Cocaine Addiction
...nduced behaviorand addiction. These insights may lead to better treatments for cocaineaddiction. # # # Please mention support for this work from the National Institute of GeneralMedical Sciences (NIGMS), a component of the National Institutes of Health thatsupports basic biomedical research. Please fax...DNA Enzyme Works In Crystal Form; Yields New Insights Into Gene Copying
...icity." While such insights won't lead directly to new cancer treatments, Beesecautions, "a greater basic understanding of the cancer process often leads toinsights about how to affect it." The biochemists also will perform experiments to sort out the chemicalsteps by which polym...3-D Structure Of HIV Components May Pave The Way For New Anti-AIDS Drugs
...spread of the virus," said Dr. Michael F. Summers, lead author ofthe study and a professor of biophysical and bioinorganic chemistry at theUniversity of Maryland Baltimore County (UMBC). Dr. Summers is also anassociate investigator of the Howard Hughes Medical Institute. Like a father recognizing his chi...Termites' Attraction To Small Amounts Of Carbon Dioxide Lures Pests To Their Deaths
...olorado State University scientist's discovery may lead to asafer and cheaper way to prevent termites from infesting homes, where they causean estimated $750 million in damage in the United States annually. Entomologist Louis Bjostad found that termites' natural reliance oncarbon dioxide to find f......fection that can persist for decadesand eventually lead to cirrhosis, liver failure and liver cancer withdevastating health consequences. Sources at the U.S. Centers for DiseaseControl and Prevention (CDC) recently estimated that approximately 3.9 millionAmericans, or more than one percent of the popula......istakes cause mutations and, in certain genes, can lead to cancer. Editors: A more detailed version of this story is available on request. Theother researchers on this project include lecturer Stanley Tabor, who figuredout the biochemical conditions to enable crystallography, postdoctoral fellowSylvie Dou...Cellular 'Short Circuit' Causes Insulin Resistance
...e and diabetes. These findings may in the future lead to new treatments for diabetesthat would be based on correcting insulin resistance. ADDITIONAL INFORMATION Prof. Zick's team included Ph.D. student Keren Paz, Dr. EytanElhanany of the Israel Institute for Biological Research, Dr. HannahKanety, Pr...Maillinckrodt Medical Licenses Invention For Concentration Of Rhenium Radioisotopes
...rship between private business and government can lead to something that can benefit thousands of people and improve their quality of life," Knapp said. ORNL, one of DOE's multiprogram research facilities, is managed by Lockheed Martin Energy Research Corporation....UMass Researchers Announce Birth Of Genetically Modified Cloned Calves
...c engineering. The calves are notable because they lead the way to the production of similar animals that produce very large quantities of therapeutic human proteins, essentially, medications for people in their milk. These proteins can either be extracted and purified, then taken in the form of a pill or...Memorial Sloan-Kettering Investigators
...ned how to interfere with the genetic changes that lead tothis potentially fatal type of cancer. In laboratory studies, the investigatorsidentified a combination of drugs that turn on proteins called transcriptionfactors, which may be turned off in leukemia. The drug duo induces leukemiacells to mature a...Gene For Inherited Syndrome Is Possible New Tumor Suppressor
... responsible for a rareinherited disorder that can lead to cancer inmany different organs. Unexpectedly, t...shed this month in the journal Nature, will likely lead to atest that can be used to unequivocally diagnosisindividuals with PJS and detect family members w...Gene Therapy Enables Transplantation Without Immunosuppressive Drugs
...Olthoff, MD, an assistant professor of surgery and lead author on the study."So, to protect the new organ from rejection, long-term drugs that suppress theentire immune system must be given, making the person susceptible to infections,cancers, and a number of other complications, including nerve and kidne...Infants, Toddlers Should Not Restrict Fat Intake, Experts Say
...l calories in young children may reduce growth and lead to nutritional shortages. The relative low-fat nature of infant formula is a special concern for these researchers. "Certain fatty acids are found only in human milk. They are not found in sufficient amounts in infant formulas," Hennig says. "The com......on the entire human haircycle. The discovery could lead to a better understanding of the hair cycle and,eventually, more effective treatments for various forms of hair loss. The research, reported in the Jan. 30 issue of Science, suggests thatthe gene initiates a cascade of events that stimulate ...