Tag: "leukemia" at biology news
Two studies add to the growing evidence that green tea is beneficial for health, according to the
... damage caused by iron treatment in cultured human leukemia
cells.Results showed that green tea protects cells from injury. Increasing intake of green tea may helpreduce oxidative damage associated with various disease processes. Says Sheri Zidenberg-Cherr, PhD, a representative of the Public Information Com...
Cooperative action of two proteins causes damaged cells to "self-destruct"
...rethan 90 percent of patients with chronic myeloid leukemia
have a unique abnormality known as thePhiladelphia chromosome, characterized by c-Abl mutations. Shaul therefore decided to examine whatc-Abl's role is in safeguarding the cell. A Family of Tumor Suppressors The Weizmann team found that irradiation...
Study may help clarify how cells grow
... is looking at tumor cells, or in particular human leukemia
cells, where there may be a dysregulation of the normal nucleotide biosynthetic pathways and determining whether or not phosphorolation mediated by MAP kinase is adding to that problem," Graves said. "If so, this may help us to design new therapies t...
Mutations not the only gene defect that leads to cancer
... said. "In some tumor types -- leukemia
and head and neck cancer, for example -- certain genes are methylated in very specific places, and we can use those sites as markers for certain tumor types." Aberrant DNA methylation may t...
$11-million grant supports study of how genes affect cancer chemotherapy
...damage leading a secondary and often fatal form of leukemia
years after the initial treatment. "We have alrea...nts are at a higher risk for the secondary form of leukemia
because of a mutation in one of the genes that metabolize the anticancer drugs they receive," said R...
UC Berkeley biologist disputes current dogma that genetic mutation is the cause of cancer
...solid tumors -- so-called to distinguish them from leukemia
and similar immune system cancers -- whose cells contain a normal number of chromosomes are those very rare ones caused by retroviruses. Otherwise, some 5,000 known solid tumors have chromosome disruptions. Bialy concluded that in a new, dynamic theo...
No apparent increase in cancer deaths among Three Mile Island residents, report University of Pittsburgh researchers
...ood-forming organs), excluding chronic lymphocytic leukemia
and Hodgkin's disease; and the central nervous system. Thyroid cancer was considered, but no deaths were reported during the study period. Initial results indicated a significantly higher mortality from all causes among the TMI population as compared...
Benzene responsible for high percentage of leukemia deaths induced by smoking
...en 8 percent and 48 percent of all smoking-induced leukemia
deaths, a new University of North Carolina at Chap...down from different studies that have been done on leukemia
and people exposed to benzene in the workplace and established what's called a dose-response curve,"...
Fact sheet: the Report on Carcinogens - 9th edition
.... The Report cites findings of increased risk for leukemia
and non-Hodgkin's lymphoma in workers exposed to ethylene oxide. This information coupled with data on its genotoxic and biochemical interactions with human DNA led to the upgrading to a "known human carcinogen." Tamoxifen - Tamoxifen is listed i...
AVAX Technologies' M-Vax cancer vaccine extends five-year overall survival in patients with lymph node metastatic melanoma
... Tokyo, and a Phase 1/2 trial in acute myelogenous leukemia
(L-Vax) at the MD Anderson Cancer Center....
Princeton scientists describe genetics of blood stem cells
...rocess from getting out of hand, as it does in the leukemia
blood cancers, or how are the correct proportions of mature blood cells produced on a daily basis throughout life? In addition to yielding a wealth of new genetic information, the research demonstrates an innovative approach to collecting, analyzing ...
Weizmann Institute scientists develop a novel system for analyzing genetic data that mimics the human capacity for unsupervised learning
..., picking up differences in the gene expression of leukemia
patients that had received treatment versus those that had not. The ability to monitor cell response to treatment and understand the origin of disease in each patient may improve future treatment protocols, which would be tailored to individual patho...
Science and Amersham Pharmacia Biotech grand prize: "jumping DNA" discovery explains immune system evolution
...inued transposition could be mutagenic and lead to leukemia
by activating oncogenes, inactivating tumor suppressor genes, or creating chromosomal translations." Research has not yet demonstrated jumping-DNA transposition in living cells, Agrawal emphasized. But, she added: "It's somewhat logical that errors i...
Penn researchers protein's link to leukemia
...unlock a mystery related to acute undifferentiated leukemia
Scientists studying gene regulation by a commo...Nobody knows why this is so but we do know that in leukemia
patients it is always found fused to a second protein called CAN," Chakravarti said. The function of...
JAK-STAT signaling keeps leukemia cells alive
Large granular lymphocyte (LGL) leukemia
is characterized by the clonal expansion of a T-ce...kemic cells. While prior studies of other types of leukemia
and solid tumors had suggested STAT activation might promote resistance to apoptosis via induction o...
Million dollar grant by the Paul G. Allen Foundation for Medical Research to University of Washington medical scientist program
...thesis, Lauring studied the pathogenesis of feline leukemia
virus, which serves as a model system for both hum...nd AIDS. Knowledge of how the virus causes feline leukemia
could provide clues to how HIV, a similar virus, causes human AIDS. Lauring is from St. Petersburg,...
Molecular mimicry and neurodegenerative disease
...to the GluR proteins after being infected with the leukemia
virus LP-BM5. Self-specific antibodies accumulate in the neocortex and elsewhere in the brain, and Koustova et al. find that such brain-derived autoantibodies are biologically active, activating calcium channels in cultured cells and blocking intera...
Common genetic differences affect vulnerability to childhood leukemia, new study shows
... children are protected against different types of leukemia
depending on which form of an enzyme they have for...earch suggests that scrutiny of genetic changes in leukemia
cells -- at the DNA level -- can reveal potential causes specific to each type of leukemia." Wiemels...
General clinical research center at Wake Forest University Baptist Medical Center awarded $14.7 million
...histicated cancer drug treatments targeted to kill leukemia
cells. We've conducted a NASA nutrition study to prevent kidney stones in space, and we've tested inhaled insulin as a painless way to treat diabetes." The grant, from the National Institutes of Health's National Center for Research Resources, pays...
Hopkins' Young Investigators' Day winners shine in the spotlight
...When I was a medical student in China, I noticed a leukemia
patient listening to his small radio every morning when we did rounds. One day, his roommate died. The next morning, the young man, with his radio in his hand, asked me, Do you know why I am always listening? I wish one morning, when I wake up, t...
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